Journal of Clinical Oncology, Vol 12, 213-225, Copyright © 1994 by American Society of Clinical Oncology
The cancer anorexia-cachexia syndrome
KA Nelson, D Walsh and FA Sheehan
Department of Hematology/Medical Oncology, Cleveland Clinic Foundation, OH 44195.
PURPOSE: To review the research related to the anorexia-cachexia syndrome
in patients with cancer, with attention to the etiology and symptomatic
treatment. DESIGN: A comprehensive literature review using MEDLINE. RESULTS
AND CONCLUSION: The anorexia-cachexia syndrome is a common problem in
advanced cancer. Although many possible etiologies have been investigated,
the cause has not been determined. Appropriate clinical evaluation is
necessary to identify those patients who may respond to available,
symptomatic treatments.

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