Journal of Clinical Oncology, Vol 12, 1718-1723, Copyright © 1994 by American Society of Clinical Oncology
The Community Clinical Oncology Program (CCOP) story: review of community oncologists' experiences with clinical research trials in cancer with an emphasis on the CCOP of the National Cancer Institute between 1982 and 1987
RW Frelick
Community Clinical Oncology Program, National Cancer Institute, Bethesda, MD.
PURPOSE: To review the growth of community physicians' involvement in
National Cancer Institute (NCI) clinical research trials as a significant
contribution to cancer control, and to show their impact, not yet fully
realized, on cancer morbidity and mortality in the United States. DESIGN:
Background information, based on the personal experience of participants,
as well as a review of pertinent literature, portrays the evolution of the
clinical research component of community oncology in the United States over
the last 25 years. RESULTS: Data from Community Clinical Oncology Programs
(CCOPs) I and II have been used to outline some of the results of this
far-reaching program. CONCLUSION: The CCOP was introduced at an appropriate
time to expand the clinical trial resources of the NCI, while at the same
time helping community oncologists practice state-of-the-art cancer
management found in the research protocols. This in turn provided improved
resources to manage cancer patients, as most of them are treated in their
own communities. CCOPs have also indirectly had a positive impact on the
trial processes of the NCI cooperative groups and comprehensive cancer
centers, and have helped to widen the scope and hasten progress in
cancer-control research and practice.
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