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Journal of Clinical Oncology, Vol 15, 3347-3349, Copyright © 1997 by American Society of Clinical Oncology

ARTICLES

Successful pregnancy after allogeneic bone marrow transplant with embryos isolated before transplant

JH Lipton, M Virro and H Solow
Department of Medicine, Princess Margaret Hospital and University of Toronto, Ontario, Canada. jeffrey_lipton@pmh.toronto.on.ca

METHODS AND RESULTS: Autologous embryos from in vitro-fertilized ova were successfully implanted in a 29-year-old woman, 2 years after successful allogeneic bone marrow transplant (BMT) for chronic myeloid leukemia (CML). A second pregnancy, similarly initiated, is in progress at 4 years posttransplant. CONCLUSION: Our experience offers a fertility-salvaging technique to some women after cytotoxic therapy, where time permits ovarian hyperstimulation before the need for definitive myeloblative therapy of their malignancy, and where the risk of subsequent infertility is high.


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Copyright © 1997 by the American Society of Clinical Oncology, Online ISSN: 1527-7755. Print ISSN: 0732-183X
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