Journal of Clinical Oncology, Vol 17, Issue 3
(March), 1999: 976
© 1999 American Society for Clinical Oncology
Multi-Institutional Melanoma Lymphatic Mapping Experience: The Prognostic Value of Sentinel Lymph Node Status in 612 Stage I or II Melanoma Patients
Jeffrey E. Gershenwald,
William Thompson,
Paul F. Mansfield,
Jeffrey E. Lee,
Maria I. Colome,
Chi-hong Tseng,
J. Jack Lee,
Charles M. Balch,
Douglas S. Reintgen,
Merrick I. Ross
From the Departments of Surgical Oncology, Pathology, and Biomathematics, The University of Texas M.D. Anderson Cancer Center, Houston, TX; and the Cutaneous Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.
Address reprint requests to Merrick I. Ross, MD, Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Box 106, Houston, TX 77030.
PURPOSE: To compare the effect of pathologic sentinel lymph node (SLN) status with that of other known prognostic factors on recurrence and survival in patients with stage I or II cutaneous melanoma.
PATIENTS AND METHODS: We reviewed the records of 612 patients with primary cutaneous melanoma who underwent lymphatic mapping and SLN biopsy between January 1991 and May 1995 to determine the effects of tumor thickness, ulceration, Clark level, location, sex, and SLN pathologic status on disease-free and disease-specific survival.
RESULTS: In the 580 patients in whom lymphatic mapping and SLN biopsy were successful, the SLN was positive by conventional histology in 85 patients (15%) but negative in 495 patients (85%). SLN status was the most significant prognostic factor with respect to disease-free and disease-specific survival by univariate and multiple covariate analyses. Although tumor thickness and ulceration influenced survival in SLN-negative patients, they provided no additional prognostic information in SLN-positive patients.
CONCLUSION: Lymphatic mapping and SLN biopsy is highly accurate in staging nodal basins at risk for regional metastases in primary melanoma patients and identifies those who may benefit from earlier lymphadenectomy. Furthermore, pathologic status of the SLN in these patients with clinically negative nodes is the most important prognostic factor for recurrence. The information from SLN biopsy is particularly helpful in establishing stratification criteria for future adjuvant trials.
Presented at the 49th Annual Meeting of the Society of Surgical Oncology, Atlanta, GA, March 1996.
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|
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|
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|
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144(4):
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|
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[Full Text]
[PDF]
|
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|
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|
 |
 
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March 1, 2008;
61(3):
297 - 300.
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|
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|
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|
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December 1, 2007;
14(12):
3566 - 3574.
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[Full Text]
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|
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|
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|
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October 1, 2007;
14(10):
2861 - 2866.
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|
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|

|
 |

|
 |
 
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October 1, 2007;
14(10):
2867 - 2875.
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|
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|

|
 |

|
 |
 
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August 1, 2007;
14(8):
2377 - 2383.
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|
 |
|

|
 |

|
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August 1, 2007;
133(8):
820 - 826.
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[Full Text]
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|
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|

|
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|
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Arch Surg,
August 1, 2007;
142(8):
753 - 758.
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[Full Text]
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|
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|

|
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|
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Yield and Predictors of Radiologic Studies for Identifying Distant Metastases in Melanoma Patients with a Positive Sentinel Lymph Node Biopsy
Ann. Surg. Oncol.,
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14(7):
2133 - 2140.
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|
 |
|

|
 |

|
 |
 
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Arch Ophthalmol,
July 1, 2007;
125(7):
983 - 984.
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|
 |
|

|
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|
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June 1, 2007;
14(6):
1934 - 1942.
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|
 |
|

|
 |

|
 |
 
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14(5):
1596 - 1603.
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|
 |
|

|
 |

|
 |
 
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Ann. Surg. Oncol.,
May 1, 2007;
14(5):
1604 - 1611.
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[Full Text]
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|
 |
|

|
 |

|
 |
 
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25(7):
869 - 875.
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|
 |
|

|
 |

|
 |
 
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January 18, 2007;
356(3):
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|
 |
|

|
 |

|
 |
 
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Ann. Surg. Oncol.,
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13(12):
1655 - 1663.
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|
 |
|

|
 |

|
 |
 
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Ann. Surg. Oncol.,
December 1, 2006;
13(12):
1664 - 1670.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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J. Clin. Oncol.,
October 1, 2006;
24(28):
4565 - 4569.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Clinical relevance of melanoma micrometastases (<0.1 mm) in sentinel nodes: are these nodes to be considered negative?
Ann. Onc.,
October 1, 2006;
17(10):
1578 - 1585.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Sentinel-node biopsy or nodal observation in melanoma.
N. Engl. J. Med.,
September 28, 2006;
355(13):
1307 - 1317.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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N. Engl. J. Med.,
September 28, 2006;
355(13):
1370 - 1371.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Ann. Surg. Oncol.,
August 1, 2006;
13(8):
1113 - 1122.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Invasive Squamous Cell Carcinoma of the Skin: Defining a High-Risk Group
Ann. Surg. Oncol.,
July 1, 2006;
13(7):
902 - 909.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Level of Fluorodeoxyglucose Uptake Predicts Risk for Recurrence in Melanoma Patients Presenting With Lymph Node Metastases
Ann. Surg. Oncol.,
July 1, 2006;
13(7):
919 - 926.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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The Prognostic Importance of Sentinel Lymph Node Biopsy in Thin Melanoma
Ann. Surg. Oncol.,
July 1, 2006;
13(7):
927 - 932.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K. D. Lewis, W. A. Robinson, M. McCarter, N. Pearlman, S. J. O'Day, C. Anderson, T. T. Amatruda, A. Baron, C. Zeng, M. Becker, et al.
Phase II Multicenter Study of Neoadjuvant Biochemotherapy for Patients With Stage III Malignant Melanoma
J. Clin. Oncol.,
July 1, 2006;
24(19):
3157 - 3163.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. R. Scoggins, M. I. Ross, D. S. Reintgen, R. D. Noyes, J. S. Goydos, P. D. Beitsch, M. M. Urist, S. Ariyan, B. S. Davidson, J. J. Sussman, et al.
Prospective Multi-Institutional Study of Reverse Transcriptase Polymerase Chain Reaction for Molecular Staging of Melanoma
J. Clin. Oncol.,
June 20, 2006;
24(18):
2849 - 2857.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. A. Aloia, J. E. Gershenwald, R. H. Andtbacka, M. M. Johnson, C. W. Schacherer, C. S. Ng, J. N. Cormier, J. E. Lee, M. I. Ross, and P. F. Mansfield
Utility of Computed Tomography and Magnetic Resonance Imaging Staging Before Completion Lymphadenectomy in Patients With Sentinel Lymph Node-Positive Melanoma
J. Clin. Oncol.,
June 20, 2006;
24(18):
2858 - 2865.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. M. Thomas
In Reply
J. Clin. Oncol.,
June 20, 2006;
24(18):
2966 - 2967.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Value of sentinel node status as a prognostic factor in melanoma: prospective observational study
BMJ,
June 17, 2006;
332(7555):
1423.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. L. Wong, D. L. Morton, J. F. Thompson, J. E. Gershenwald, S. P. L. Leong, D. S. Reintgen, H. Gutman, M. S. Sabel, G. W. Carlson, K. M. McMasters, et al.
Melanoma Patients with Positive Sentinel Nodes Who Did Not Undergo Completion Lymphadenectomy: A Multi-Institutional Study
Ann. Surg. Oncol.,
June 1, 2006;
13(6):
809 - 816.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Z. Belhocine, A. M. Scott, E. Even-Sapir, J.-L. Urbain, and R. Essner
Role of Nuclear Medicine in the Management of Cutaneous Malignant Melanoma
J. Nucl. Med.,
June 1, 2006;
47(6):
957 - 967.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. J.C.L.M. Vuylsteke, B. G. Molenkamp, P. A.M. van Leeuwen, S. Meijer, P. G.J.T.B. Wijnands, J. B.A.G. Haanen, R. J. Scheper, and T. D. de Gruijl
Tumor-Specific CD8+ T Cell Reactivity in the Sentinel Lymph Node of GM-CSF-Treated Stage I Melanoma Patients is Associated with High Myeloid Dendritic Cell Content.
Clin. Cancer Res.,
May 1, 2006;
12(9):
2826 - 2833.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
G. C. Karakousis, P. A. Gimotty, J. D. Botbyl, S. B. Kesmodel, D. E. Elder, R. Elenitsas, M. E. Ming, D. Guerry, D. L. Fraker, B. J. Czerniecki, et al.
Predictors of Regional Nodal Disease in Patients With Thin Melanomas
Ann. Surg. Oncol.,
April 1, 2006;
13(4):
533 - 541.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. P. L. Leong, N. A. Accortt, R. Essner, M. Ross, J. E. Gershenwald, B. Pockaj, H. J. Hoekstra, C. Garberoglio, R. L. White Jr, D. Chu, et al.
Impact of sentinel node status and other risk factors on the clinical outcome of head and neck melanoma patients.
Arch Otolaryngol Head Neck Surg,
April 1, 2006;
132(4):
370 - 373.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. I. Ross
Early-stage melanoma: staging criteria and prognostic modeling.
Clin. Cancer Res.,
April 1, 2006;
12(7):
2312s - 2319s.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. L. Wong, M. S. Brady, K. J. Busam, and D. G. Coit
Results of Sentinel Lymph Node Biopsy in Patients With Thin Melanoma
Ann. Surg. Oncol.,
March 1, 2006;
13(3):
302 - 309.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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American Joint Committee on Cancer Clinical Stage as a Selection Criterion for Sentinel Lymph Node Biopsy in Thin Melanoma
Ann. Surg. Oncol.,
February 1, 2006;
13(2):
198 - 204.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. F. Uren
Sentinel Lymph Node Biopsy in Melanoma
J. Nucl. Med.,
February 1, 2006;
47(2):
191 - 195.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D Massi, S Puig, A Franchi, J Malvehy, S Vidal-Sicart, M Gonzalez-Cao, G Baroni, S Ketabchi, J Palou, and M Santucci
Tumour lymphangiogenesis is a possible predictor of sentinel lymph node status in cutaneous melanoma: a case-control study
J. Clin. Pathol.,
February 1, 2006;
59(2):
166 - 173.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. P. Abratt, W. H.H. Reece, N. H. Enas, and R. Stephens
Randomized phase II studies and their ethics.
J. Clin. Oncol.,
December 20, 2005;
23(36):
9443 - 9443.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. M. Thomas
Time to Re-Evaluate Sentinel Node Biopsy in Melanoma Post-Multicenter Selective Lymphadenectomy Trial
J. Clin. Oncol.,
December 20, 2005;
23(36):
9443 - 9444.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. M. Kirkwood
Building Upon the Standard of Care in Adjuvant Therapy of High-Risk Melanoma
J. Clin. Oncol.,
December 1, 2005;
23(34):
8559 - 8563.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
B. G. Molenkamp, R. J.C.L.M. Vuylsteke, P. A.M. van Leeuwen, S. Meijer, W. Vos, P. G.J.T.B. Wijnands, R. J. Scheper, and T. D. de Gruijl
Matched Skin and Sentinel Lymph Node Samples of Melanoma Patients Reveal Exclusive Migration of Mature Dendritic Cells
Am. J. Pathol.,
November 1, 2005;
167(5):
1301 - 1307.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K. N. MacNeill, D. Ghazarian, D. McCready, and L. Rotstein
Sentinel Lymph Node Biopsy for Cutaneous Melanoma of the Head and Neck
Ann. Surg. Oncol.,
September 1, 2005;
12(9):
726 - 732.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Population-Based Assessment of Surgical Treatment Trends for Patients With Melanoma in the Era of Sentinel Lymph Node Biopsy
J. Clin. Oncol.,
September 1, 2005;
23(25):
6054 - 6062.
[Abstract]
[Full Text]
[PDF]
|
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|

|
 |

|
 |
 
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Melanoma Recurrence Patterns After Negative Sentinel Lymphadenectomy
Arch Surg,
September 1, 2005;
140(9):
865 - 872.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Ann. Surg. Oncol.,
August 1, 2005;
12(8):
575 - 578.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Arch Dermatol,
August 1, 2005;
141(8):
1016 - 1022.
[Abstract]
[Full Text]
[PDF]
|
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|
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|
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23(21):
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|
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