Journal of Clinical Oncology, Vol 2, 118-123, Copyright © 1984 by American Society of Clinical Oncology
Ethiodized oil emulsion 13 in computed tomography of hepatoma
JP Dutcher, PJ Haney, NO Whitley, R Finley, P Pearl, MS Didolkar and PH Wiernik
Six patients with biopsy-proven hepatoma were prospectively evaluated both
by conventional computed tomography (CT) and by scans using ethiodized oil
emulsion 13 (EOE 13) as a contrast agent. EOE 13 infusion resulted in
marked improvement in the demonstration of the neoplasm in all cases and
allowed more accurate definition of tumor extent than was possible with
standard scanning techniques. In two cases EOE 13 enhancement was essential
for complete radiographic depiction of tumor location, size, and extent.
EOE 13 also proved to be of considerable value in assessment of therapeutic
response in three patients, permitting more objective determination of
tumor growth or regression. EOE 13--enhanced CT scanning provides a
valuable means of staging patients presenting with hepatoma and is a
reliable, accurate means of radiographic follow-up.