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Health-Related Quality of Life and Symptom Management Research Sponsored by the National Cancer Institute

Lori M. Minasian, Ann M. O'Mara, Bryce B. Reeve, Andrea M. Denicoff, Joseph Kelaghan, Julia H. Rowland, Edward L. Trimble

From the Divisions of Cancer Prevention, Cancer Control and Population Sciences, and Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD

Address reprint requests to Lori M. Minasian, MD, Community Oncology and Prevention Trials Research Group, 6130 Executive Blvd, MSC-7340, EPN, Rm 2016, Bethesda, MD 20892-7340; e-mail: minasilo{at}mail.nih.gov

For almost 30 years, the National Cancer Institute (NCI) has sponsored health-related quality-of-life (HRQOL) measures in cancer research as a means of including the patient's experience. The scope of NCI's research in symptom management and HRQOL is described with attention to its evolution over time and the next steps, through the Clinical Trials Working Group Recommendations.

The workshop entitled "Patient-Reported Outcomes Assessment in Cancer Trials: Evaluating and Enhancing the Payoff to Decision Making" was supported by the Division of Cancer Prevention, the Division of Cancer Treatment and Diagnosis, and the Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, and by the American Cancer Society.

Authors' disclosures of potential conflicts of interest and author contributions are found at the end of this article.

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