Journal of Clinical Oncology, Vol 25, No 8 (March 10), 2007: pp. 1009-1013
© 2007 American Society of Clinical Oncology.
DOI: 10.1200/JCO.2006.10.4638
Future Issues in Highly Conformal Radiotherapy for Head and Neck Cancer
Mary Feng,
Avraham Eisbruch
From the Department of Radiation Oncology, University of Michigan, Ann Arbor, MI
Address reprint requests to Avraham Eisbruch, MD, University of Michigan Hospital, Department of Radiation Oncology, 1500 E Medical Center Dr, UH B2C490 Box 0010, Ann Arbor, MI 48109; e-mail: eisbruch{at}med.umich.edu
Improving the conformity of the radiation dose to targets in the head and neck promises reduced toxicity and, in some cases, potentially improved local-regional tumor control. Intensity-modulated radiotherapy (IMRT) is a method that allows highly conformal delivery of radiotherapy. In recent years, its use has spread rapidly in both academic and community radiation oncology facilities. The use of IMRT has raised multiple issues related to target definition, optimal treatment delivery methods, and the need to account for anatomic changes occurring during therapy. Some of these issues are reviewed in this article.
Authors' disclosures of potential conflicts of interest and author contributions are found at the end of this article.

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