Journal of Clinical Oncology, Vol 26, No 5 (February 10), 2008: pp. 703-711
© 2008 American Society of Clinical Oncology.
DOI: 10.1200/JCO.2007.14.3594
Who Should Have Breast Magnetic Resonance Imaging Evaluation?
Susan Orel
From the Department of Radiology/Breast Imaging, Hospital of the University of Pennsylvania, Philadelphia, PA
Corresponding author: Susan Orel, MD, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104; e-mail: Susan.Orel{at}uphs.upenn.edu
During the last two decades, tremendous advances have been made in the performance and interpretation of breast magnetic resonance imaging (MRI) examinations. Technical requirements for optimal breast imaging including the requirement for a breast MRI biopsy system are now being defined as part of a voluntary American College of Radiology (ACR) breast MRI accreditation program. The ACR BI-RADS (Breast Imaging Reporting and Data System) lexicon for breast MRI has brought uniformity to the interpretation of breast MRI examinations. With these advances in imaging technique, interpretation guidelines, and increasing availability of MR-compatible breast biopsy systems, MRI of the breast is rapidly gaining popularity in clinical practice in both the diagnostic setting and, more recently, in the screening setting. The clinical indications for breast MRI, however, remain to be defined. There are clinical indications that have emerged where MRI, as an adjunct to mammography, seems to be the imaging study of choice. There are other indications, specifically breast cancer staging, in which MRI is being utilized with increasing frequency, but in which controversy persists.
Author's disclosures of potential conflicts of interest and author contributions are found at the end of this article.

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