Originally published as JCO Early Release 10.1200/JCO.2008.21.1441 on March 2 2009

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Email this article to a colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Save to my personal folders Download to citation manager Rights & Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Nathan, P. C. Articles by Oeffinger, K. C. Search for Related Content PubMed PubMed Citation Articles by Nathan, P. C. Articles by Oeffinger, K. C. Social Bookmarking                            What's this?

Health Behaviors, Medical Care, and Interventions to Promote Healthy Living in the Childhood Cancer Survivor Study Cohort

From the Hospital for Sick Children, Toronto, Ontario, Canada; Memorial Sloan-Kettering Cancer Center, New York, NY; University of Chicago Pritzker School of Medicine, Chicago, IL; St Jude Children's Research Hospital, Memphis, TN; Dana-Farber Cancer Institute and Harvard School of Public Health, Boston, MA; University of California, Los Angeles; and Alcohol Research Group, Emeryville, CA.

Corresponding author: Kevin C. Oeffinger, MD, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021; e-mail: oeffingk{at}mskcc.org.

Childhood cancer survivors are at risk for medical and psychosocial late effects as a result of their cancer and its therapy. Promotion of healthy lifestyle behaviors and provision of regular risk-based medical care and surveillance may modify the evolution of these late effects. This manuscript summarizes publications from the Childhood Cancer Survivor Study (CCSS) that have examined health behaviors, risk-based health care, and interventions to promote healthy lifestyle practices. Long-term survivors use tobacco and alcohol and have inactive lifestyles at higher rates than is ideal given their increased risk of cardiac, pulmonary, and metabolic late effects. Nearly 90% of survivors report receiving some form of medical care. However, only 18% report medical visits related to their prior cancer that include discussion or ordering of screening tests or counseling on how to reduce the specific risks arising from their cancer. One low-cost, peer-driven intervention trial has been successful in improving smoking cessation within the CCSS cohort. On the basis of data from CCSS investigations, several trials to promote improved medical surveillance among high-risk groups within the cohort are underway. Despite their long-term risks, many survivors of childhood cancer engage in risky health behaviors and do not receive adequate risk-based medical care.

Supported by Grant No. U24 CA55727 (L.L.R.) from the National Cancer Institute, Bethesda, MD, with additional support provided to St Jude Children's Research Hospital by the American Lebanese Syrian Associated Charities (ALSAC).

Authors' disclosures of potential conflicts of interest and author contributions are found at the end of this article.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Facebook    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				L. A. Jacobs, S. C. Palmer, L. A. Schwartz, A. DeMichele, J. J. Mao, J. Carver, C. Gracia, C. E. Hill-Kayser, J. M. Metz, M. K. Hampshire, et al. Adult Cancer Survivorship: Evolution, Research, and Planning Care CA Cancer J Clin, November 1, 2009; 59(6): 391 - 410. [Abstract] [Full Text] [PDF]