Originally published as JCO Early Release 10.1200/JCO.2009.22.6126 on September 8 2009

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Catheter-Associated Thrombosis in Patients With Malignancy

From the Department of Medicine, Dalhousie University and Capital District Health Authority, Halifax, Nova Scotia, Canada.

Corresponding author: Stephen Couban, MD, Department of Medicine, Dalhousie University, Room 417 Bethune Building, 1278 Tower Rd, Halifax, Nova Scotia, B3H 2Y9 Canada; e-mail: Stephen.Couban{at}cdha.nshealth.ca.

Central venous catheters are widely used in the care of patients with cancer. Indwelling catheters are associated with upper extremity deep venous thrombosis in some patients, and recognition of this entity is an important aspect of treating patients with malignancies. This article will review the incidence, pathogenesis, clinical presentation, diagnosis, treatment, and prophylaxis of catheter-assocated thrombosis in patients with malignancy. The care of pediatric patients with malignancy and catheter-associated thrombosis will also be addressed.

Authors' disclosures of potential conflicts of interest and author contributions are found at the end of this article.

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