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Publisher’s Note

The February 20, 2009, article by Huguet et al, entitled, “Pediatric-Inspired Therapy in Adults With Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia: The GRAALL-2003 Study” (J Clin Oncol 27:911-918, 2009), was published in print with errors in Table 1. This article was also published online on January 5, 2009, with errors in Table 1.

Under “Remission induction,” the term “corticosteroid prophase” was given, whereas it should have been “corticosteroid prephase.” The dose for L-asparaginase was given as, “6,000 U/m²/d on days 8, 10, 12, 18, 20, 22, 24, and 26,” and it should have been, “6,000 U/m²/d on days 8, 10, 12, 20, 22, 24, 26, and 28.” Also, the dose for cyclophosphamide (CPM) was given as, “750 mg/m²/d on days 1 and 8; 750 mg/m² on day 15 in good early responders; 500 mg/m²/12 h on days 15 and 16 in poor early responders,” and should have been, “750 mg/m²/d on day 1; 750 mg/m²/d on day 15 in good early responders; 500 mg/m²/12 h on days 15 and 16 in poor early responders.”

Under “Consolidation blocks 3, 6, and 9,” the dose for CPM was given as, “500 mg/m² on days 29 and 30,” and should have been, “500 mg/m²/d on days 29 and 30.” Also, the dose for VP-16 was given as, “75 mg/m²m/d on days 29 and 30,” and should have been, “75 mg/m²/d on days 29 and 30.”

Under “Late intensification (between consolidation blocks 6 and 7),” the dose for lenograstim was not indicated for patients in complete remission after the first induction course, and should have been, “150 µg/m²/d if neutrophils < 0.5 G/L to myeloid recovery.”

Under “Maintenance therapy,” the dose for prednisone (PDN) was given as, “40 mg/m²/d on days 1-14 monthly for 12 months,” and should have been, “40 mg/m²/d on days 1-7 monthly for 12 months.”

Under “CNS therapy, Treatment of patients with initial CNS involvement,” the dose for triple IT injections was given as, “Eight between days 7 and 21 of induction; four during the first two consolidation blocks; one at day 29 of consolidation blocks 3 and 6,” and should have been, “Eight between days -7 and 21 of induction; four during the first two consolidation blocks; one at day 29 of consolidation blocks 3 and 6.” Also, the dose for cranial irradiation was given as, “15 Gy before SCT or 18 Gy before late intensification; 6-MP 60 mg/m²/d during irradiation,” and should have been, “15 Gy before SCT or 24 Gy before maintenance therapy initiation; 6-MP 60 mg/m²/d during irradiation.”

Also under “CNS therapy,” the footnote for triple IT injections was given as:

 †Triple IT injections consisted of MTX 15 mg, Ara-C 40 mg, and PDN 40 mg.

While it should have been:

 †Triple IT injections consisted of MTX 15 mg, Ara-C 40 mg, and methylprednisolone 40 mg.

These corrections have been made online as of May 12, 2009. These corrections are not reflected in the February 20, 2009, print edition. An erratum for the print edition was published in the May 20, 2009, issue (J Clin Oncol 27:2574, 2009).

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