EDITORIALS

Does Palliative Care Palliate?

Alice B. Kornblith

JCO Apr 15 2001: 2111–2113. [Full Text] [PDF]

ORIGINAL REPORTS
Lung Cancer
	Topotecan Versus Observation After Cisplatin Plus Etoposide in Extensive-Stage Small-Cell Lung Cancer: E7593—A Phase III Trial of the Eastern Cooperative Oncology Group
	Joan H. Schiller, Sudeshna Adak, David Cella, Russell F. DeVore, III, and David H. Johnson
	JCO Apr 15 2001: 2114–2122. [Abstract] [Full Text] [PDF]
	Prospective Study on Quality of Life Before and After Radical Radiotherapy in Non–Small-Cell Lung Cancer
	J. A. Langendijk, N. K. Aaronson, J. M.A. de Jong, G. P.M. ten Velde, M. J. Muller, R. J. Lamers, B. J. Slotman, and E. F.M. Wouters
	JCO Apr 15 2001: 2123–2133. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Hematopoietic Stem-Cell Transplantation for Treatment-Related Leukemia or Myelodysplasia
	Robert P. Witherspoon, H. Joachim Deeg, Barry Storer, Claudio Anasetti, Rainer Storb, and Frederick R. Appelbaum
	JCO Apr 15 2001: 2134–2141. [Abstract] [Full Text] [PDF]
	Evaluation of the Combination of Nelarabine and Fludarabine in Leukemias: Clinical Response, Pharmacokinetics, and Pharmacodynamics in Leukemia Cells
	Varsha Gandhi, William Plunkett, Steve Weller, Min Du, Mary Ayres, Carlos O. Rodriguez, Jr, Prameen Ramakrishna, Gary L. Rosner, Jeff P. Hodge, Susan O’Brien, and Michael J. Keating
	JCO Apr 15 2001: 2142–2152. [Abstract] [Full Text] [PDF]
	Rituximab Using A Thrice Weekly Dosing Schedule in B-Cell Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma Demonstrates Clinical Activity and Acceptable Toxicity
	John C. Byrd, Timothy Murphy, Robin S. Howard, Margaret S. Lucas, Amy Goodrich, Kathy Park, Michael Pearson, Jamie K. Waselenko, Geoffrey Ling, Michael R. Grever, Antonio J. Grillo-Lopez, Jay Rosenberg, Lori Kunkel, and Ian W. Flinn
	JCO Apr 15 2001: 2153–2164. [Abstract] [Full Text] [PDF]
	Rituximab Dose-Escalation Trial in Chronic Lymphocytic Leukemia
	Susan M. O’Brien, Hagop Kantarjian, Deborah A. Thomas, Francis J. Giles, Emil J. Freireich, Jorge Cortes, Susan Lerner, and Michael J. Keating
	JCO Apr 15 2001: 2165–2170. [Abstract] [Full Text] [PDF]
	Chemotherapy for Human Immunodeficiency Virus–Associated Non-Hodgkin’s Lymphoma in Combination With Highly Active Antiretroviral Therapy
	Lee Ratner, Jeannette Lee, Shenghui Tang, David Redden, Fayez Hamzeh, Brian Herndier, David Scadden, Lawrence Kaplan, Richard Ambinder, Alexandra Levine, William Harrington, Louise Grochow, Charles Flexner, Benjamin Tan, and David Straus
	JCO Apr 15 2001: 2171–2178. [Abstract] [Full Text] [PDF]
	Natural Killer/Natural Killer-Like T-Cell Lymphoma, CD56+, Presenting in the Skin: An Increasingly Recognized Entity With an Aggressive Course
	Serena Mraz-Gernhard, Yasodha Natkunam, Richard T. Hoppe, Philip LeBoit, Sabine Kohler, and Youn H. Kim
	JCO Apr 15 2001: 2179–2188. [Abstract] [Full Text] [PDF]

Brain Tumors
	Results of a Pilot Study Involving the Use of an Antisense Oligodeoxynucleotide Directed Against the Insulin-Like Growth Factor Type I Receptor in Malignant Astrocytomas
	David W. Andrews, Mariana Resnicoff, Adam E. Flanders, Lawrence Kenyon, Mark Curtis, Gino Merli, Renato Baserga, George Iliakis, and Robert D. Aiken
	JCO Apr 15 2001: 2189–2200. [Abstract] [Full Text] [PDF]

Bone Marrow Transplantation
	Oral Mucositis and the Clinical and Economic Outcomes of Hematopoietic Stem-Cell Transplantation
	Stephen T. Sonis, Gerry Oster, Hank Fuchs, Lisa Bellm, Williamson Z. Bradford, John Edelsberg, Vanessa Hayden, June Eilers, Joel B. Epstein, Francis G. LeVeque, Carole Miller, Douglas E. Peterson, Mark M. Schubert, Frederik K.L. Spijkervet, and Mary Horowitz
	JCO Apr 15 2001: 2201–2205. [Abstract] [Full Text] [PDF]

Palliative Care
	Individualized Patient Education and Coaching to Improve Pain Control Among Cancer Outpatients
	Jennifer Wright Oliver, Richard L. Kravitz, Sherrie H. Kaplan, and Frederick J. Meyers
	JCO Apr 15 2001: 2206–2212. [Abstract] [Full Text] [PDF]

Breast Cancer
	Accelerated-Intensified Cyclophosphamide, Epirubicin, and Fluorouracil (CEF) Compared With Standard CEF in Metastatic Breast Cancer Patients: Results of a Multicenter, Randomized Phase III Study of the Italian Gruppo Oncologico Nord-Ouest–Mammella Inter Gruppo Group
	Lucia Del Mastro, Marco Venturini, Rita Lionetto, Flavio Carnino, Domenico Guarneri, Luigi Gallo, Antonio Contu, Paolo Pronzato, Lorella Vesentini, Marina Bergaglio, Silvia Comis, and Riccardo Rosso
	JCO Apr 15 2001: 2213–2221. [Abstract] [Full Text] [PDF]
	Clinical and Pharmacologic Study of the Epirubicin and Paclitaxel Combination in Women With Metastatic Breast Cancer
	Giacomo Grasselli, Lucia Viganò, Giuseppe Capri, Alberta Locatelli, Emiliana Tarenzi, Carlo Spreafico, Alexia Bertuzzi, Antonio Giani, Carlo Materazzo, Sara Cresta, Antonella Perotti, P. Valagussa, and Luca Gianni
	JCO Apr 15 2001: 2222–2231. [Abstract] [Full Text] [PDF]
	Dose-Dense Sequential Chemotherapy With Epirubicin and Paclitaxel Versus the Combination, as First-Line Chemotherapy, in Advanced Breast Cancer: A Randomized Study Conducted by the Hellenic Cooperative Oncology Group
	George Fountzilas, Christos Papadimitriou, Urania Dafni, Dimitrios Bafaloukos, Dimosthenis Skarlos, Lia A. Moulopoulos, Evangelia Razis, Haralambos P. Kalofonos, Gerassimos Aravantinos, Evangelos Briassoulis, Pavlos Papakostas, Konstantina Abela, Eleni Gogas, Paris Kosmidis, Nicholas Pavlidis, and Meletios A. Dimopoulos
	JCO Apr 15 2001: 2232–2239. [Abstract] [Full Text] [PDF]
	Impact of Systemic Treatment on Local Control for Patients With Lymph Node–Negative Breast Cancer Treated With Breast-Conservation Therapy
	Thomas A. Buchholz, Susan L. Tucker, Jessica Erwin, Daniel Mathur, Eric A. Strom, Marsha D. McNeese, Gabriel N. Hortobagyi, Massimo Cristofanilli, Francisco J. Esteva, Lisa Newman, S. Eva Singletary, Aman U. Buzdar, and Kelly K. Hunt
	JCO Apr 15 2001: 2240–2246. [Abstract] [Full Text] [PDF]
	Germline Mutations in BRCA1 and BRCA2 in Breast-Ovarian Families From a Breast Cancer Risk Evaluation Clinic
	A.-M. Martin, M.A. Blackwood, D. Antin-Ozerkis, H.A. Shih, K. Calzone, T.A. Colligon, S. Seal, N. Collins, M.R. Stratton, B.L. Weber, and K.L. Nathanson
	JCO Apr 15 2001: 2247–2253. [Abstract] [Full Text] [PDF]
	Factors Predicting the Use of Breast-Conserving Therapy in Stage I and II Breast Carcinoma
	Monica Morrow, Julia White, Jennifer Moughan, Jean Owen, Thomas Pajack, JoAnne Sylvester, J. Frank Wilson, and David Winchester
	JCO Apr 15 2001: 2254–2262. [Abstract] [Full Text] [PDF]
	Risk Factors for Recurrence and Metastasis After Breast-Conserving Therapy for Ductal Carcinoma-In-Situ: Analysis of European Organization for Research and Treatment of Cancer Trial 10853
	Nina Bijker, Johannes L. Peterse, Luc Duchateau, Jean-Pierre Julien, Ian S. Fentiman, Christian Duval, Silvana Di Palma, Joëlle Simony-Lafontaine, Isabelle de Mascarel, and Marc J. van de Vijver
	JCO Apr 15 2001: 2263–2271. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Analysis of p53/BAX/p16ink4a/CDKN2 in Esophageal Squamous Cell Carcinoma: High BAX and p16ink4a/CDKN2 Identifies Patients With Good Prognosis
	Isrid Sturm, Henrik Petrowsky, Roland Volz, Matthias Lorenz, Silke Radetzki, Timo Hillebrand, Gerhard Wolff, Steffen Hauptmann, Bernd Dörken, and Peter T. Daniel
	JCO Apr 15 2001: 2272–2281. [Abstract] [Full Text] [PDF]
	Comparison of Oral Capecitabine Versus Intravenous Fluorouracil Plus Leucovorin as First-Line Treatment in 605 Patients With Metastatic Colorectal Cancer: Results of a Randomized Phase III Study
	Paulo M. Hoff, Rafat Ansari, Gerald Batist, John Cox, Walter Kocha, Mario Kuperminc, Jean Maroun, David Walde, Charles Weaver, Evelyn Harrison, Hans U. Burger, Bruno Osterwalder, Alfred O. Wong, and Ralf Wong
	JCO Apr 15 2001: 2282–2292. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Preponderance of Thiopurine S-Methyltransferase Deficiency and Heterozygosity Among Patients Intolerant to Mercaptopurine or Azathioprine
	William E. Evans, Yuen Yi Hon, Lisa Bomgaars, Steve Coutre, Mark Holdsworth, Robert Janco, David Kalwinsky, Frank Keller, Ziad Khatib, Judy Margolin, Jeffrey Murray, John Quinn, Y. Ravindranath, Kim Ritchey, William Roberts, Zora R. Rogers, Deborah Schiff, Charles Steuber, Fabio Tucci, Nancy Kornegay, Eugene Y. Krynetski, and Mary V. Relling
	JCO Apr 15 2001: 2293–2301. [Abstract] [Full Text] [PDF]
	Patterns of Intellectual Development Among Survivors of Pediatric Medulloblastoma: A Longitudinal Analysis
	Shawna L. Palmer, Olga Goloubeva, Wilburn E. Reddick, John O. Glass, Amar Gajjar, Larry Kun, Thomas E. Merchant, and Raymond K. Mulhern
	JCO Apr 15 2001: 2302–2308. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I Clinical and Pharmacokinetic Study of Rebeccamycin Analog NSC 655649 Given Daily for Five Consecutive Days
	Afshin Dowlati, Charles L. Hoppel, Stephen T. Ingalls, Susan Majka, Xiaolin Li, Nell Sedransk, Timothy Spiro, Stanton L. Gerson, Percy Ivy, and Scot C. Remick
	JCO Apr 15 2001: 2309–2318. [Abstract] [Full Text] [PDF]
	Phase I Trial of 72-Hour Continuous Infusion UCN-01 in Patients With Refractory Neoplasms
	Edward A. Sausville, Susan G. Arbuck, Richard Messmann, Donna Headlee, Kenneth S. Bauer, Richard M. Lush, Anthony Murgo, William D. Figg, Tyler Lahusen, Susan Jaken, Xiu-xian Jing, Michel Roberge, Eiichi Fuse, Takashi Kuwabara, and Adrian M. Senderowicz
	JCO Apr 15 2001: 2319–2333. [Abstract] [Full Text] [PDF]

REVIEW ARTICLES
	When Is a Tumor Marker Ready for Prime Time? A Case Study of c-erbB-2 as a Predictive Factor in Breast Cancer
	Hideko Yamauchi, Vered Stearns, and Daniel F. Hayes
	JCO Apr 15 2001: 2334–2356. [Abstract] [Full Text] [PDF]
	Hormone Replacement Therapy After Breast Cancer: A Systematic Review and Quantitative Assessment of Risk
	Nananda F. Col, Linda K. Hirota, Richard K. Orr, John K. Erban, John B. Wong, and Joseph Lau
	JCO Apr 15 2001: 2357–2363. [Abstract] [Full Text] [PDF]

SPECIAL DEPARTMENTS

Announcements

ANNOUNCEMENTS

JCO Apr 15 2001: 2367–2369. [Full Text] [PDF]

CORRESPONDENCE

Surgery in Advanced Epithelial Ovarian Cancer

M. Steven Piver, Paul J. Hoskins, and E. Eisenhauer

JCO Apr 15 2001: 2364. [Full Text] [PDF]

Nodal Metastasis is Highly Consistent in Squamous Cell Carcinoma of the Vulva

Richard T. Penson and Arlan F. Fuller, Jr

JCO Apr 15 2001: 2364-a–2365. [Full Text] [PDF]

Intangible Risks of Complementary and Alternative Medicine

Edzard Ernst

JCO Apr 15 2001: 2365–2366. [Full Text] [PDF]

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