EDITORIALS

Radiation Dose Escalation in Combined-Modality Therapy for Esophageal Cancer

Christopher G. Willett

JCO Mar 1 2002: 1151–1153. [Full Text] [PDF]

Substitute "Prostate Cancer" for "Neuroblastoma"?

William G. Woods

JCO Mar 1 2002: 1154–1155. [Full Text] [PDF]

Cardiac Dysfunction in the Trastuzumab Clinical Experience

James Speyer

JCO Mar 1 2002: 1156–1157. [Full Text] [PDF]

Is There a "Best" Choice of Second-Line Agent in the Treatment of Recurrent, Potentially Platinum-Sensitive Ovarian Cancer?

Stephen A. Cannistra

JCO Mar 1 2002: 1158–1160. [Full Text] [PDF]

Recurrent Ovarian Cancer: Evidence-Based Treatment

Robert F. Ozols

JCO Mar 1 2002: 1161–1163. [Full Text] [PDF]

Risk Management in BRCA1 and BRCA2 Mutation Carriers: Lessons Learned, Challenges Posed

Angela DeMichele and Barbara L. Weber

JCO Mar 1 2002: 1164–1166. [Full Text] [PDF]

ORIGINAL REPORTS
Gastrointestinal Cancer
	INT 0123 (Radiation Therapy Oncology Group 94-05) Phase III Trial of Combined-Modality Therapy for Esophageal Cancer: High-Dose Versus Standard-Dose Radiation Therapy
	Bruce D. Minsky, Thomas F. Pajak, Robert J. Ginsberg, Thomas M. Pisansky, James Martenson, Ritsuko Komaki, Gordon Okawara, Seth A. Rosenthal, and David P. Kelsen
	JCO Mar 1 2002: 1167–1174. [Abstract] [Full Text] [PDF]
	Phase II Trial of Chronomodulated Infusion of High-Dose Fluorouracil and l-Folinic Acid in Previously Untreated Patients With Metastatic Colorectal Cancer
	H. Curé, V. Chevalier, A. Adenis, N. Tubiana-Mathieu, G. Niezgodzki, F. Kwiatkowski, D. Pezet, B. Perpoint, B. Coudert, C. Focan, F. Lévi, J. Chipponi, and P. Chollet
	JCO Mar 1 2002: 1175–1181. [Abstract] [Full Text] [PDF]
	Irinotecan Plus Gemcitabine Induces Both Radiographic and CA 19-9 Tumor Marker Responses in Patients With Previously Untreated Advanced Pancreatic Cancer
	Caio Max S. Rocha Lima, Diane Savarese, Howard Bruckner, Arkadiusz Dudek, John Eckardt, John Hainsworth, Furhan Yunus, Eric Lester, William Miller, Wayne Saville, Gary L. Elfring, Paula K. Locker, Linda D. Compton, Langdon L. Miller, and Mark R. Green
	JCO Mar 1 2002: 1182–1191. [Abstract] [Full Text] [PDF]
	Age, Sex, and Racial Differences in the Use of Standard Adjuvant Therapy for Colorectal Cancer
	Arnold L. Potosky, Linda C. Harlan, Richard S. Kaplan, Karen A. Johnson, and Charles F. Lynch
	JCO Mar 1 2002: 1192–1202. [Abstract] [Full Text] [PDF]
	Mutations of hMLH1 and hMSH2 in Patients With Suspected Hereditary Nonpolyposis Colorectal Cancer: Correlation With Microsatellite Instability and Abnormalities of Mismatch Repair Protein Expression
	Mario Scartozzi, Francesca Bianchi, Saverio Rosati, Eva Galizia, Annalisa Antolini, Cristian Loretelli, Andrea Piga, Italo Bearzi, Riccardo Cellerino, and Emilio Porfiri
	JCO Mar 1 2002: 1203–1208. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Marginal Decrease in Mortality and Marked Increase in Incidence as a Result of Neuroblastoma Screening at 6 Months of Age: Cohort Study in Seven Prefectures in Japan
	Keiko Yamamoto, Shigeru Ohta, Etsuro Ito, Yutaka Hayashi, Tadashi Asami, Osamu Mabuchi, Masamune Higashigawa, and Masako Tanimura
	JCO Mar 1 2002: 1209–1214. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Cardiac Dysfunction in the Trastuzumab Clinical Trials Experience
	Andrew Seidman, Clifford Hudis, Mary Kathryn Pierri, Steven Shak, Virginia Paton, Mark Ashby, Maureen Murphy, Stanford J. Stewart, and Deborah Keefe
	JCO Mar 1 2002: 1215–1221. [Abstract] [Full Text] [PDF]
	Phase I and Pharmacologic Study of Liposomal Lurtotecan, NX 211: Urinary Excretion Predicts Hematologic Toxicity
	Diederik F.S. Kehrer, Annelies M. Bos, Jaap Verweij, Harry J. Groen, Walter J. Loos, Alex Sparreboom, Maja J.A. de Jonge, Marta Hamilton, Terri Cameron, and Elisabeth G.E. de Vries
	JCO Mar 1 2002: 1222–1231. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Randomized Controlled Trial of Single-Agent Paclitaxel Versus Cyclophosphamide, Doxorubicin, and Cisplatin in Patients With Recurrent Ovarian Cancer Who Responded to First-Line Platinum-Based Regimens
	M. G. Cantù, A. Buda, G. Parma, R. Rossi, I. Floriani, C. Bonazzi, T. Dell’Anna, V. Torri, and N. Colombo
	JCO Mar 1 2002: 1232–1237. [Abstract] [Full Text] [PDF]
	Retrospective Analysis of Carboplatin and Paclitaxel as Initial Second-Line Therapy for Recurrent Epithelial Ovarian Carcinoma: Application Toward a Dynamic Disease State Model of Ovarian Cancer
	Don S. Dizon, Martee L. Hensley, Elizabeth A. Poynor, Paul Sabbatini, Carol Aghajanian, Amanda Hummer, Ennapadam Venkatraman, and David R. Spriggs
	JCO Mar 1 2002: 1238–1247. [Abstract] [Full Text] [PDF]
	Survival Effect of Maximal Cytoreductive Surgery for Advanced Ovarian Carcinoma During the Platinum Era: A Meta-Analysis
	Robert E. Bristow, Rafael S. Tomacruz, Deborah K. Armstrong, Edward L. Trimble, and F. J. Montz
	JCO Mar 1 2002: 1248–1259. [Abstract] [Full Text] [PDF]

Surgical Oncology
	Outcome of Preventive Surgery and Screening for Breast and Ovarian Cancer in BRCA Mutation Carriers
	Lauren Scheuer, Noah Kauff, Mark Robson, Bridget Kelly, Richard Barakat, Jaya Satagopan, Nathan Ellis, Martee Hensley, Jeff Boyd, Patrick Borgen, Larry Norton, and Kenneth Offit
	JCO Mar 1 2002: 1260–1268. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	T-Cell/Histiocyte–Rich Large B-Cell Lymphoma: A Distinct Clinicopathologic Entity
	R. Achten, G. Verhoef, L. Vanuytsel, and C. De Wolf-Peeters
	JCO Mar 1 2002: 1269–1277. [Abstract] [Full Text] [PDF]
	CD20 Expression in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin’s Disease: Associations With Presenting Features and Clinical Outcome
	George Z. Rassidakis, L. Jeffrey Medeiros, Simonetta Viviani, Valeria Bonfante, Gian-Paolo Nadali, Theodoros P. Vassilakopoulos, Ofelia Mesina, Marco Herling, Maria K. Angelopoulou, Roberto Giardini, Marco Chilosi, Christos Kittas, Peter McLaughlin, M. Alma Rodriguez, Jorge Romaguera, Gianni Bonadonna, Alessandro M. Gianni, Giovanni Pizzolo, Gerassimos A. Pangalis, Fernando Cabanillas, and Andreas H. Sarris
	JCO Mar 1 2002: 1278–1287. [Abstract] [Full Text] [PDF]
	Rituximab and CHOP Induction Therapy for Newly Diagnosed Mantle-Cell Lymphoma: Molecular Complete Responses Are Not Predictive of Progression-Free Survival
	Orion M. Howard, John G. Gribben, Donna S. Neuberg, Michael Grossbard, Christina Poor, Milos J. Janicek, and Margaret A. Shipp
	JCO Mar 1 2002: 1288–1294. [Abstract] [Full Text] [PDF]
	Improved Outcome of Allogeneic Transplantation in High-Risk Multiple Myeloma Patients After Nonmyeloablative Conditioning
	Ashraf Badros, Bart Barlogie, Eric Siegel, Michele Cottler-Fox, Maurizio Zangari, Athanasios Fassas, Christopher Morris, Elias Anaissie, Frits Van Rhee, and Guido Tricot
	JCO Mar 1 2002: 1295–1303. [Abstract] [Full Text] [PDF]

Breast Cancer
	Incidence and Prognostic Significance of Complete Axillary Downstaging After Primary Chemotherapy in Breast Cancer Patients With T1 to T3 Tumors and Cytologically Proven Axillary Metastatic Lymph Nodes
	Roman Rouzier, Jean-Marc Extra, Jerzy Klijanienko, Marie-Christine Falcou, Bernard Asselain, Anne Vincent-Salomon, Philippe Vielh, and Edwige Bourstyn
	JCO Mar 1 2002: 1304–1310. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Quality-of-Life–Adjusted Survival Analysis of High-Dose Adjuvant Interferon Alfa-2b for High-Risk Melanoma Patients Using Intergroup Clinical Trial Data
	Kerry L. Kilbridge, Bernard F. Cole, John M. Kirkwood, Frank G. Haluska, Michael A. Atkins, John C. Ruckdeschel, Dana E. Sock, Robert F. Nease, Jr, and Jane C. Weeks
	JCO Mar 1 2002: 1311–1318. [Abstract] [Full Text] [PDF]
	Clinical Factors Associated With Cancer-Related Fatigue in Patients Being Treated for Leukemia and Non-Hodgkin’s Lymphoma
	Xin Shelley Wang, Sergio A. Giralt, Tito R. Mendoza, Martha C. Engstrom, Beth A. Johnson, Neomi Peterson, Lyle D. Broemeling, and Charles S. Cleeland
	JCO Mar 1 2002: 1319–1328. [Abstract] [Full Text] [PDF]

Sarcomas
	Increasing Single Epirubicin Doses in Advanced Soft Tissue Sarcomas
	Massimo Lopez, Patrizia Vici, Luigi Di Lauro, and Silvia Carpano
	JCO Mar 1 2002: 1329–1334. [Abstract] [Full Text] [PDF]

Lung Cancer
	Phase III Trial Comparing a Defined Duration of Therapy Versus Continuous Therapy Followed by Second-Line Therapy in Advanced-Stage IIIB/IV Non–Small-Cell Lung Cancer
	Mark A. Socinski, Michael J. Schell, Amy Peterman, Kamal Bakri, Steven Yates, Robert Gitten, Paul Unger, Joanna Lee, Ji-Hyun Lee, Maureen Tynan, Martha Moore, and Merrill S. Kies
	JCO Mar 1 2002: 1335–1343. [Abstract] [Full Text] [PDF]
	Economic Analysis of the TAX 317 Trial: Docetaxel Versus Best Supportive Care as Second-Line Therapy of Advanced Non–Small-Cell Lung Cancer
	Natasha B. Leighl, Frances A. Shepherd, Rita Kwong, Ronald L. Burkes, Ronald Feld, and Pamela J. Goodwin
	JCO Mar 1 2002: 1344–1352. [Abstract] [Full Text] [PDF]
	Prognostic Significance of Molecular Genetic Aberrations on Chromosome Segment 11p15.5 in Non–Small-Cell Lung Cancer
	Gerold Bepler, Ashish Gautam, Lauren M. McIntyre, Amy F. Beck, David S. Chervinsky, Young-Chul Kim, Diana M. Pitterle, and Andrew Hyland
	JCO Mar 1 2002: 1353–1360. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Phase III Trial of Fluorouracil, Interferon Alfa-2b, and Cisplatin Versus Methotrexate, Vinblastine, Doxorubicin, and Cisplatin in Metastatic or Unresectable Urothelial Cancer
	Arlene O. Siefker-Radtke, Randall E. Millikan, Shi-Ming Tu, Dennis F. Moore, Jr, Terry L. Smith, Dallas Williams, and Christopher J. Logothetis
	JCO Mar 1 2002: 1361–1367. [Abstract] [Full Text] [PDF]
	Mathematical Model to Predict Individual Survival for Patients With Renal Cell Carcinoma
	Amnon Zisman, Allan J. Pantuck, Fredrick Dorey, Debby H. Chao, Barbara J. Gitlitz, Nancy Moldawer, Dana Lazarovici, Jean B. deKernion, Robert A. Figlin, and Arie S. Belldegrun
	JCO Mar 1 2002: 1368–1374. [Abstract] [Full Text] [PDF]

Neurooncology
	Promising Survival for Patients With Newly Diagnosed Glioblastoma Multiforme Treated With Concomitant Radiation Plus Temozolomide Followed by Adjuvant Temozolomide
	Roger Stupp, Pierre-Yves Dietrich, Sandrine Ostermann Kraljevic, Alessia Pica, Ivan Maillard, Phillipe Maeder, Reto Meuli, Robert Janzer, Gianpaolo Pizzolato, Raymond Miralbell, François Porchet, Luca Regli, Nicolas de Tribolet, René O. Mirimanoff, and Serge Leyvraz
	JCO Mar 1 2002: 1375–1382. [Abstract] [Full Text] [PDF]
	Phase II Trial of Temozolomide Plus the Matrix Metalloproteinase Inhibitor, Marimastat, in Recurrent and Progressive Glioblastoma Multiforme
	Morris D. Groves, Vinay K. Puduvalli, Kenneth R. Hess, Kurt A. Jaeckle, Pamela Peterson, W.K. Alfred Yung, and Victor A. Levin
	JCO Mar 1 2002: 1383–1388. [Abstract] [Full Text] [PDF]
	Phase II Trial of Murine 131I-Labeled Antitenascin Monoclonal Antibody 81C6 Administered Into Surgically Created Resection Cavities of Patients With Newly Diagnosed Malignant Gliomas
	David A. Reardon, Gamal Akabani, R. Edward Coleman, Allan H. Friedman, Henry S. Friedman, James E. Herndon, II, Ilkcan Cokgor, Roger E. McLendon, Charles N. Pegram, James M. Provenzale, Jennifer A. Quinn, Jeremy N. Rich, Lorna V. Regalado, John H. Sampson, Timothy D. Shafman, Carol J. Wikstrand, Terence Z. Wong, Xiao-Guang Zhao, Michael R. Zalutsky, and Darell D. Bigner
	JCO Mar 1 2002: 1389–1397. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Standardized Uptake Value of 2-[18F] Fluoro-2-Deoxy-D-Glucose in Predicting Outcome in Head and Neck Carcinomas Treated by Radiotherapy With or Without Chemotherapy
	Abdelkarim S. Allal, Pavel Dulguerov, Mohamed Allaoua, Charles-André Haenggeli, El Abbes El Ghazi, Willy Lehmann, and Daniel O. Slosman
	JCO Mar 1 2002: 1398–1404. [Abstract] [Full Text] [PDF]
	Maximizing Local Control and Organ Preservation in Stage IV Squamous Cell Head and Neck Cancer With Hyperfractionated Radiation and Concurrent Chemotherapy
	David J. Adelstein, Jerrold P. Saxton, Pierre Lavertu, Lisa A. Rybicki, Ramon M. Esclamado, Benjamin G. Wood, Marshall Strome, and Marjorie A. Carroll
	JCO Mar 1 2002: 1405–1410. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Skin Lesions in Melanoma and Kaposi’s Sarcoma: Case 1. Detection of Circulating Malignant Cells by RT-PCR in a Case of Cutaneous Melanoma in Complete Regression

Daniele Santini, Giuseppe Tonini, Bruno Vincenzi, Raffaele Murace, Giulio Ferranti, and Alfonso Baldi

JCO Mar 1 2002: 1411–1412. [Full Text] [PDF]

Skin Lesions in Melanoma and Kaposi’s Sarcoma: Case 2. Dermoscopic Features of Metastases From Cutaneous Melanoma Mimicking Benign Nevi and Primary Melanoma

Maria A. Pizzichetta, Vincenzo Canzonieri, Alessandro Gatti, Clelia de Giacomi, Giusto Trevisan, Andrea Veronesi, and H. Peter Soyer

JCO Mar 1 2002: 1412–1415. [Full Text] [PDF]

Skin Lesions in Melanoma and Kaposi’s Sarcoma: Case 3. Familial Classic Mediterranean Kaposi's Sarcoma

Farid Fata, Ayoub Mirza, and Albert Bernath

JCO Mar 1 2002: 1415–1418. [Full Text] [PDF]

ART OF ONCOLOGY

Discussing Hospice Care

Charles F. von Gunten

JCO Mar 1 2002: 1419–1424. [Full Text] [PDF]

SPECIAL DEPARTMENTS

CORRESPONDENCE

Combined Chemotherapy Trials Require Combined Pharmacogenetic Approaches

Michael Steiner, Peter Schuff-Werner, Mathias Freund, Claus-Henning Köhne, James P. Stevenson, Alexander S. Whitehead, and Peter J. O’Dwyer

JCO Mar 1 2002: 1425–1426. [Full Text] [PDF]

Impact of High-Dose Chemotherapy on Peripheral T-Cell Lymphomas

Nicolas Mounier, Daniele Simon, Corinne Haioun, Philippe Gaulard, Christian Gisselbrecht, and Issa Khouri

JCO Mar 1 2002: 1426–1427. [Full Text] [PDF]

Adjuvant Radiation Therapy After Complete Resection of Non–Small-Cell Lung Cancer

Eric Vallières, Mitchell Machtay, Eli Glatstein, and James A. Bonner

JCO Mar 1 2002: 1427–1429. [Full Text] [PDF]

Unexpected Toxicity of Combination Thalidomide and Interferon Alfa-2a Treatment in Metastatic Renal Cell Carcinoma

P. D. Nathan, M. E. Gore, and T. G. Eisen

JCO Mar 1 2002: 1429–1430. [Full Text] [PDF]

ERRATA

ERRATA

JCO Mar 1 2002: 1430. [Full Text] [PDF]

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