EDITORIALS

Will Identifying or Targeting Altered Marker Expression in Response to Cytotoxic Therapy Be of Prognostic or Therapeutic Value?

Christopher H. Crane, Howard D. Thames, and Stanley R. Hamilton

JCO Sep 15 2003: 3381–3382. First published on Jul 28 2003; 10.1200/JCO.2003.04.156. [Full Text] [PDF]

It’s What’s Inside That Counts

Donna S. Shewach and Theodore S. Lawrence

JCO Sep 15 2003: 3383–3384. First published on Jul 28 2003; 10.1200/JCO.2003.05.081. [Full Text] [PDF]

Down Syndrome and Acute Myeloid Leukemia: The Paradox of Increased Risk for Leukemia and Heightened Sensitivity to Chemotherapy

Yaddanapudi Ravindranath

JCO Sep 15 2003: 3385–3387. First published on Jul 28 2003; 10.1200/JCO.2003.05.086. [Full Text] [PDF]

Hodgkin’s Lymphoma: The Hazards of Success

Joseph M. Connors

JCO Sep 15 2003: 3388–3390. First published on Aug 4 2003; 10.1200/JCO.2003.07.001. [Full Text] [PDF]

ORIGINAL REPORTS
Gastrointestinal Cancer
	Dynamic Expression Profile of p21WAF1/CIP1 and Ki-67 Predicts Survival in Rectal Carcinoma Treated With Preoperative Radiochemotherapy
	Beate Rau, Isrid Sturm, Hermann Lage, Stefan Berger, Ulrike Schneider, Steffen Hauptmann, Peter Wust, Hanno Riess, Peter M. Schlag, Bernd Dörken, and Peter T. Daniel
	JCO Sep 15 2003: 3391–3401. First published on Jul 28 2003; 10.1200/JCO.2003.07.077. [Abstract] [Full Text] [PDF]
	Randomized Phase II Comparison of Dose-Intense Gemcitabine: Thirty-Minute Infusion and Fixed Dose Rate Infusion in Patients With Pancreatic Adenocarcinoma
	Margaret Tempero, William Plunkett, Veronique Ruiz van Haperen, John Hainsworth, Howard Hochster, Renato Lenzi, and James Abbruzzese
	JCO Sep 15 2003: 3402–3408. First published on Jul 28 2003; 10.1200/JCO.2003.09.140. [Abstract] [Full Text] [PDF]
	Treatment of Locally Advanced Pancreatic Cancer in the Real World: Population-Based Practices and Effectiveness
	Monika K. Krzyzanowska, Jane C. Weeks, and Craig C. Earle
	JCO Sep 15 2003: 3409–3414. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Increased Age at Diagnosis Has a Significantly Negative Effect on Outcome in Children With Down Syndrome and Acute Myeloid Leukemia: A Report From the Children’s Cancer Group Study 2891
	Alan S. Gamis, William G. Woods, Todd A. Alonzo, Allen Buxton, Beverly Lange, Dorothy R. Barnard, Stuart Gold, and Franklin O. Smith
	JCO Sep 15 2003: 3415–3422. First published on Jul 28 2003; 10.1200/JCO.2003.08.060. [Abstract] [Full Text] [PDF]
	Long-Term Event-Free Survival After Intensive Chemotherapy for Ewing’s Family of Tumors in Children and Young Adults
	E. Anders Kolb, Brian H. Kushner, Richard Gorlick, Caroline Laverdiere, John H. Healey, Michael P. LaQuaglia, Andrew G. Huvos, Jing Qin, Ha Thanh Vu, Leonard Wexler, Suzanne Wolden, and Paul A. Meyers
	JCO Sep 15 2003: 3423–3430. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Long-Term Cause-Specific Mortality of Patients Treated for Hodgkin’s Disease
	Berthe M.P. Aleman, Alexandra W. van den Belt-Dusebout, Willem J. Klokman, Mars B. van’t Veer, Harry Bartelink, and Flora E. van Leeuwen
	JCO Sep 15 2003: 3431–3439. First published on Jul 28 2003; 10.1200/JCO.2003.07.131. [Abstract] [Full Text] [PDF]
	Secondary Myeloid Leukemia and Myelodysplastic Syndromes in Patients Treated for Hodgkin’s Disease: A Report From the German Hodgkin’s Lymphoma Study Group
	Andreas Josting, Sabine Wiedenmann, Jeremy Franklin, Michael May, Markus Sieber, Juergen Wolf, Andreas Engert, and Volker Diehl
	JCO Sep 15 2003: 3440–3446. First published on Mar 7 2003; 10.1200/JCO.2003.07.160. [Abstract] [Full Text] [PDF]

AIDS-Related Cancer
	Incidence of Non–AIDS-Defining Cancers Before and During the Highly Active Antiretroviral Therapy Era in a Cohort of Human Immunodeficiency Virus–Infected Patients
	Magid Herida, Murielle Mary-Krause, Régis Kaphan, Jacques Cadranel, Isabelle Poizot-Martin, Christian Rabaud, Nathalie Plaisance, Hervé Tissot-Dupont, François Boue, Jean-Marie Lang, and Dominique Costagliola
	JCO Sep 15 2003: 3447–3453. [Abstract] [Full Text] [PDF]

Breast Cancer
	Phase I and II Study of Exisulind in Combination With Capecitabine in Patients With Metastatic Breast Cancer
	Lajos Pusztai, Jim Hou Zhen, Banu Arun, Edgardo Rivera, Clark Whitehead, W. Joseph Thompson, Kimberly M. Nealy, Amy Gibbs, W. Fraser Symmans, Francisco J. Esteva, Daniel Booser, James L. Murray, Vicente Valero, Terry L. Smith, and Gabriel N. Hortobagyi
	JCO Sep 15 2003: 3454–3461. [Abstract] [Full Text] [PDF]
	Addition of Either Lonidamine or Granulocyte Colony-Stimulating Factor Does Not Improve Survival in Early Breast Cancer Patients Treated With High-Dose Epirubicin and Cyclophosphamide
	Paola Papaldo, Massimo Lopez, Enrico Cortesi, Eugenio Cammilluzzi, Mauro Antimi, Edmondo Terzoli, Giuseppe Lepidini, Patrizia Vici, Carlo Barone, Gianluigi Ferretti, Serena Di Cosimo, Cecilia Nisticò, Paolo Carlini, Francesca Conti, Luigi Di Lauro, Claudio Botti, Carlo Vitucci, Alessandra Fabi, Diana Giannarelli, and Paolo Marolla
	JCO Sep 15 2003: 3462–3468. [Abstract] [Full Text] [PDF]
	Detection of Isolated Tumor Cells in Bone Marrow Is an Independent Prognostic Factor in Breast Cancer
	G. Wiedswang, E. Borgen, R. Kåresen, G. Kvalheim, J.M. Nesland, H. Qvist, E. Schlichting, T. Sauer, J. Janbu, T. Harbitz, and B. Naume
	JCO Sep 15 2003: 3469–3478. [Abstract] [Full Text] [PDF]

Unknown Primary Site Cancer
	Cisplatin in Combination With Either Gemcitabine or Irinotecan in Carcinomas of Unknown Primary Site: Results of a Randomized Phase II Study—Trial for the French Study Group on Carcinomas of Unknown Primary (GEFCAPI 01)
	Stéphane Culine, Alain Lortholary, Jean-Jacques Voigt, Roland Bugat, Christine Théodore, Frank Priou, Marie-Christine Kaminsky, Thierry Lesimple, Xavier Pivot, Bruno Coudert, Jean-Yves Douillard, Yacine Merrouche, Jelila Allouache, Alain Goupil, Sylvie Négrier, Juliette Viala, Peter Petrow, Jeannine Bouzy, Agnès Laplanche, and Karim Fizazi
	JCO Sep 15 2003: 3479–3482. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Quantitative Tumor Apoptosis Imaging Using Technetium-99m–HYNIC Annexin V Single Photon Emission Computed Tomography
	Christophe Van de Wiele, Christophe Lahorte, Hubert Vermeersch, D. Loose, Kris Mervillie, Neil D. Steinmetz, Jean-Luc Vanderheyden, Claude A. Cuvelier, Guido Slegers, and Rudi A. Dierck
	JCO Sep 15 2003: 3483–3487. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Trends in Surgery and Chemotherapy for Women Diagnosed With Ovarian Cancer in the United States
	Linda C. Harlan, Limin X. Clegg, and Edward L. Trimble
	JCO Sep 15 2003: 3488–3494. [Abstract] [Full Text] [PDF]
	Small-Cell Carcinoma of the Cervix: Fourteen Years of Experience at a Single Institution Using a Combined-Modality Regimen of Involved-Field Irradiation and Platinum-Based Combination Chemotherapy
	P.J. Hoskins, K.D. Swenerton, J.A. Pike, P. Lim, C. Aquino-Parsons, F. Wong, and N. Lee
	JCO Sep 15 2003: 3495–3501. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Beyond the Development of Health-Related Quality-of-Life (HRQOL) Measures: A Checklist for Evaluating HRQOL Outcomes in Cancer Clinical Trials—Does HRQOL Evaluation in Prostate Cancer Research Inform Clinical Decision Making?
	Fabio Efficace, Andrew Bottomley, David Osoba, Carolyn Gotay, Henning Flechtner, Sven D’haese, and Alfredo Zurlo
	JCO Sep 15 2003: 3502–3511. [Abstract] [Full Text] [PDF]
	Health Status and Quality of Life in Patients With Early-Stage Hodgkin’s Disease Treated on Southwest Oncology Group Study 9133
	Patricia A. Ganz, Carol M. Moinpour, Donna K. Pauler, Alice B. Kornblith, Ellen R. Gaynor, Stanley P. Balcerzak, Gretchen S. Gatti, Harry P. Erba, Sheryl McCoy, Oliver W. Press, and Richard I. Fisher
	JCO Sep 15 2003: 3512–3519. [Abstract] [Full Text] [PDF]
	Catheter Design Influences Recurrence of Catheter-Related Bloodstream Infection in Children With Cancer
	Patricia M. Flynn, Brian Willis, Aditya H. Gaur, and Jerry L. Shenep
	JCO Sep 15 2003: 3520–3525. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Emerging Applications of the Tumor Necrosis Factor Family of Ligands and Receptors in Cancer Therapy
	Anas Younes and Marshall E. Kadin
	JCO Sep 15 2003: 3526–3534. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Unusual Abdominal and Pelvic Tumors: CASE 1. AGGRESSIVE ANGIOMYXOMA OF THE PELVIS: RESPONSE TO LUTEINIZING HORMONE-RELEASING HORMONE AGONIST

Madeleine Poirier, Richard Fraser, and Sarkis Meterissian

JCO Sep 15 2003: 3535–3536. [Full Text] [PDF]

Unusual Abdominal and Pelvic Tumors: CASE 2. SPONTANEOUS REGRESSION OF PERITONEAL IMPLANTS IN BORDERLINE OVARIAN TUMOR AFTER SALPINGO-OOPHORECTOMY

P. Morice, A. Thoury, J.C. Sabourin, S. Camatte, D. Atallah, J.P. Armand, P. Madelenat, P. Duvillard, and D. Castaigne

JCO Sep 15 2003: 3536–3538. [Full Text] [PDF]

Unusual Abdominal and Pelvic Tumors: CASE 3. RESECTION OF ORIGINALLY INOPERABLE LIVER METASTASES OF GASTROINTESTINAL STROMAL TUMOR AFTER IMATINIB MESYLATE THERAPY

István Láng, Erika Hitre, Zsolt Horváth, and Mária Godény

JCO Sep 15 2003: 3538–3540. [Full Text] [PDF]

Unusual Abdominal and Pelvic Tumors: CASE 4. HYPERTROPHIC OSTEOARTHROPATHY ASSOCIATED WITH PULMONARY METASTASIS OF UTERINE LEIOMYOSARCOMA

Raquel Andrés, Alberto Saenz, José I. Mayordomo, Pedro Zaballos, Dolores Isla, Pilar Escudero, Ignacio Alvarez, Eduardo Polo, Ricardo Lara, and Alejandro Tres

JCO Sep 15 2003: 3540–3541. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Bevacizumab, Bleeding, Thrombosis, and Warfarin

Saadettin Kilickap, Hüseyin Abali, and Ismail Celik

JCO Sep 15 2003: 3542. [Full Text] [PDF]

Treatment of Metastatic Colorectal Cancer With Monoclonal Antibody to Vascular Endothelial Growth Factor: Does the Metastatic Site Make the Difference?

Francesco Graziano and Stefano Cascinu

JCO Sep 15 2003: 3542-a–3543. [Full Text] [PDF]

In reply:

Fairooz Kabbinavar

JCO Sep 15 2003: 3543. [Full Text] [PDF]

Can Colorectal Cancer Patients With Thymidylate Synthase–Overexpressing Liver Metastases Have an Overall Survival Advantage With Hepatic Arterial Infusion Alone?

A. Alimonti, G. Ferretti, S. Di Cosimo, F. Cognetti, and A. Vecchione

JCO Sep 15 2003: 3543-a–3544. [Full Text] [PDF]

In reply:

Mithat Gonen, Debabrata Banerjee, Joseph Bertino, and Nancy Kemeny

JCO Sep 15 2003: 3544–3545. [Full Text] [PDF]

Fish Oil Supplementation in Patients With Advanced Cancer

Lucy Wall

JCO Sep 15 2003: 3545. [Full Text] [PDF]

In reply:

Eduardo Bruera

JCO Sep 15 2003: 3545-a–3546. [Full Text] [PDF]

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