EDITORIALS

Of Looking Back and Looking Forward

Daniel G. Haller

JCO Jan 1 2004: 1–3. [Full Text] [PDF]

Scheduling of Fluorouracil: A Forget-Me-Not in the Jungle of Doublets

Alberto F. Sobrero

JCO Jan 1 2004: 4–6. First published on Dec 9 2003; 10.1200/JCO.2004.11.974. [Full Text] [PDF]

Adjuvant Interferon Therapy for Melanoma: High-Dose, Low-Dose, No Dose, Which Dose?

Lynn M. Schuchter

JCO Jan 1 2004: 7–10. First published on Dec 9 2003; 10.1200/JCO.2004.10.907. [Full Text] [PDF]

Present Status and Future Prospects for Adjuvant Therapy of Melanoma: Time to Build upon the Foundation of High-dose Interferon Alfa-2b

Stergios J. Moschos, John M. Kirkwood, and Panagiotis A. Konstantinopoulos

JCO Jan 1 2004: 11–14. First published on Dec 9 2003; 10.1200/JCO.2004.10.952. [Full Text] [PDF]

Chemotherapy or Combined Modality Treatment: The Optimal Treatment for Hodgkin's Disease

Volker Diehl

JCO Jan 1 2004: 15–18. First published on Dec 2 2003; 10.1200/JCO.2004.10.910. [Full Text] [PDF]

The Need for Adverse Effects Reporting Standards in Oncology Clinical Trials

Andy Trotti and Søren M. Bentzen

JCO Jan 1 2004: 19–22. First published on Dec 2 2003; 10.1200/JCO.2004.10.911. [Full Text] [PDF]

ORIGINAL REPORTS
Gastrointestinal Cancer
	A Randomized Controlled Trial of Fluorouracil Plus Leucovorin, Irinotecan, and Oxaliplatin Combinations in Patients With Previously Untreated Metastatic Colorectal Cancer
	Richard M. Goldberg, Daniel J. Sargent, Roscoe F. Morton, Charles S. Fuchs, Ramesh K. Ramanathan, Stephen K. Williamson, Brian P. Findlay, Henry C. Pitot, and Steven R. Alberts
	JCO Jan 1 2004: 23–30. First published on Dec 9 2003; 10.1200/JCO.2004.09.046. [Abstract] [Full Text] [PDF]
	Multicenter Phase II Study of Nordic Fluorouracil and Folinic Acid Bolus Schedule Combined With Oxaliplatin As First-Line Treatment of Metastatic Colorectal Cancer
	Halfdan Sørbye, Bengt Glimelius, Åke Berglund, Tone Fokstuen, Kjell Magne Tveit, Morten Brændengen, Dagfinn Øgreid, and Olav Dahl
	JCO Jan 1 2004: 31–38. [Abstract] [Full Text] [PDF]
	Colon Cancer Screening Practices After Genetic Counseling and Testing for Hereditary Nonpolyposis Colorectal Cancer
	Donald W. Hadley, Jean F. Jenkins, Eileen Dimond, Maria de Carvalho, Ilan Kirsch, and Christina G.S. Palmer
	JCO Jan 1 2004: 39–44. [Abstract] [Full Text] [PDF]
	Phase I Trial of Combined-Modality Therapy for Localized Esophageal Cancer: Escalating Doses of Continuous-Infusion Paclitaxel With Cisplatin and Concurrent Radiation Therapy
	Baruch Brenner, David H. Ilson, Bruce D. Minsky, Manjit S. Bains, William Tong, Mithat Gonen, and David P. Kelsen
	JCO Jan 1 2004: 45–52. [Abstract] [Full Text] [PDF]

Melanoma
	Adjuvant Interferon in High-Risk Melanoma: The AIM HIGH Study—United Kingdom Coordinating Committee on Cancer Research Randomized Study of Adjuvant Low-Dose Extended-Duration Interferon Alfa-2a in High-Risk Resected Malignant Melanoma
	B.W. Hancock, K. Wheatley, S. Harris, N. Ives, G. Harrison, J.M. Horsman, M.R. Middleton, N. Thatcher, P.C. Lorigan, J.R. Marsden, L. Burrows, and M. Gore
	JCO Jan 1 2004: 53–61. First published on Dec 9 2003; 10.1200/JCO.2004.03.185. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Consolidation Radiation After Complete Remission in Hodgkin's Disease Following Six Cycles of Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine Chemotherapy: Is There a Need?
	S. Laskar, T. Gupta, S. Vimal, M.A. Muckaden, T.K. Saikia, S.K. Pai, K.N. Naresh, and K.A. Dinshaw
	JCO Jan 1 2004: 62–68. First published on Dec 2 2003; 10.1200/JCO.2004.01.021. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Final Results of the 94–01 French Head and Neck Oncology and Radiotherapy Group Randomized Trial Comparing Radiotherapy Alone With Concomitant Radiochemotherapy in Advanced-Stage Oropharynx Carcinoma
	Fabrice Denis, Pascal Garaud, Etienne Bardet, Marc Alfonsi, Christian Sire, Thierry Germain, Philippe Bergerot, Beatrix Rhein, Jacques Tortochaux, and Gilles Calais
	JCO Jan 1 2004: 69–76. First published on Dec 2 2003; 10.1200/JCO.2004.08.021. [Abstract] [Full Text] [PDF]
	Multicenter Phase II Study of Erlotinib, an Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck
	Denis Soulieres, Neil N. Senzer, Everett E. Vokes, Manuel Hidalgo, Sanjiv S. Agarwala, and Lillian L. Siu
	JCO Jan 1 2004: 77–85. [Abstract] [Full Text] [PDF]

Breast Cancer
	The Combination of p53 Mutation and neu/erbB-2 Amplification Is Associated With Poor Survival in Node-Negative Breast Cancer
	Shelley B. Bull, Hilmi Ozcelik, Dushanthi Pinnaduwage, Martin E. Blackstein, Donald A.J. Sutherland, Kathleen I. Pritchard, Anjela T. Tzontcheva, Saul Sidlofsky, Wedad M. Hanna, Ali H. Qizilbash, Mary E. Tweeddale, Sheldon Fine, David R. McCready, and Irene L. Andrulis
	JCO Jan 1 2004: 86–96. [Abstract] [Full Text] [PDF]
	Axillary Treatment in Conservative Management of Operable Breast Cancer: Dissection or Radiotherapy? Results of a Randomized Study With 15 Years of Follow-Up
	Christine Louis-Sylvestre, Krishna Clough, Bernard Asselain, Jacques René Vilcoq, Remy Jacques Salmon, François Campana, and Alain Fourquet
	JCO Jan 1 2004: 97–101. [Abstract] [Full Text] [PDF]
	Menopausal Status Dependence of Early Mortality Reduction Due to Diagnosis of Smaller Breast Cancers (T1 v T2-T3): Relevance to Screening
	Romano Demicheli, Gianni Bonadonna, William J.M. Hrushesky, Michael W. Retsky, and Pinuccia Valagussa
	JCO Jan 1 2004: 102–107. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Combination Chemotherapy With Gemcitabine Plus Oxaliplatin in Patients With Intensively Pretreated or Refractory Germ Cell Cancer: A Study of the German Testicular Cancer Study Group
	C. Kollmannsberger, J. Beyer, R. Liersch, P. Schoeffski, B. Metzner, J.T. Hartmann, O. Rick, K. Stengele, K. Hohloch, C. Spott, L. Kanz, and C. Bokemeyer
	JCO Jan 1 2004: 108–114. [Abstract] [Full Text] [PDF]
	Phase II Trial of PS-341 in Patients With Renal Cell Cancer: A University of Chicago Phase II Consortium Study
	Nancy B. Davis, David A. Taber, Rafat H. Ansari, Christopher W. Ryan, Christopher George, Everett E. Vokes, Nicholas J. Vogelzang, and Walter M. Stadler
	JCO Jan 1 2004: 115–119. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Biweekly 72-Hour 9-Aminocamptothecin Infusion As Second-Line Therapy for Ovarian Carcinoma: Phase II Study of the New York Gynecologic Oncology Group and the Eastern Cooperative Oncology Group
	Howard Hochster, Elizabeth R. Plimack, Carolyn D. Runowicz, James Speyer, Robert C. Wallach, Joan Sorich, John Mandeli, Scott Wadler, John Wright, and Franco M. Muggia
	JCO Jan 1 2004: 120–126. [Abstract] [Full Text] [PDF]

Lung Cancer
	Phase II Trial of Cisplatin/Etoposide and Concurrent Radiotherapy Followed by Paclitaxel/Carboplatin Consolidation for Limited Small-Cell Lung Cancer: Southwest Oncology Group 9713
	Martin J. Edelman, Kari Chansky, Laurie E. Gaspar, Bryan Leigh, Geoffrey R. Weiss, Sarah A. Taylor, John Crowley, Robert Livingston, and David R. Gandara
	JCO Jan 1 2004: 127–132. [Abstract] [Full Text] [PDF]

Neurooncology
	Phase II Trial of Gefitinib in Recurrent Glioblastoma
	Jeremy N. Rich, David A. Reardon, Terry Peery, Jeannette M. Dowell, Jennifer A. Quinn, Kara L. Penne, Carol J. Wikstrand, Lauren B. Van Duyn, Janet E. Dancey, Roger E. McLendon, James C. Kao, Timothy T. Stenzel, B.K. Ahmed Rasheed, Sandra E. Tourt-Uhlig, James E. Herndon, II, James J. Vredenburgh, John H. Sampson, Allan H. Friedman, Darell D. Bigner, and Henry S. Friedman
	JCO Jan 1 2004: 133–142. First published on Nov 24 2003; 10.1200/JCO.2004.08.110. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Group II Rhabdomyosarcoma and Rhabdomyosarcomalike Tumors: Is Radiotherapy Necessary?
	Andreas Schuck, Adrian C. Mattke, Bernhard Schmidt, Denise S. Kunz, Dieter Harms, Robert Knietig, Joern Treuner, and Ewa Koscielniak
	JCO Jan 1 2004: 143–149. [Abstract] [Full Text] [PDF]
	Pilot Study of Idarubicin-Based Intensive-Timing Induction Therapy for Children With Previously Untreated Acute Myeloid Leukemia: Children's Cancer Group Study 2941
	Beverly J. Lange, Patricia Dinndorf, Franklin O. Smith, Carola Arndt, Dorothy Barnard, Stephen Feig, James Feusner, Nita Seibel, Margie Weiman, Richard Aplenc, Robert Gerbing, and Todd A. Alonzo
	JCO Jan 1 2004: 150–156. [Abstract] [Full Text] [PDF]

Radiation Oncology
	Neurocognitive Function and Progression in Patients With Brain Metastases Treated With Whole-Brain Radiation and Motexafin Gadolinium: Results of a Randomized Phase III Trial
	Christina A. Meyers, Jennifer A. Smith, Andrea Bezjak, Minesh P. Mehta, James Liebmann, Tim Illidge, Ian Kunkler, Jean-Michel Caudrelier, Peter D. Eisenberg, Jacobus Meerwaldt, Ross Siemers, Christian Carrie, Laurie E. Gaspar, Walter Curran, See-Chun Phan, Richard A. Miller, and Markus F. Renschler
	JCO Jan 1 2004: 157–165. [Abstract] [Full Text] [PDF]

Surgical Oncology
	Impact of Hospital Procedure Volume on Surgical Operation and Long-Term Outcomes in High-Risk Curatively Resected Rectal Cancer: Findings From the Intergroup 0114 Study
	Jeffrey A. Meyerhardt, Joel E. Tepper, Donna Niedzwiecki, Donna R. Hollis, Deborah Schrag, John Z. Ayanian, Michael J. O'Connell, Jane C. Weeks, Robert J. Mayer, Christopher G. Willett, John S. MacDonald, Al B. Benson, III, and Charles S. Fuchs
	JCO Jan 1 2004: 166–174. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I Study of the Humanized Antiepidermal Growth Factor Receptor Monoclonal Antibody EMD72000 in Patients With Advanced Solid Tumors That Express the Epidermal Growth Factor Receptor
	Udo Vanhoefer, Mitra Tewes, Federico Rojo, Olaf Dirsch, Norbert Schleucher, Oliver Rosen, Joachim Tillner, Andreas Kovar, Ada H. Braun, Tanja Trarbach, Siegfried Seeber, Andreas Harstrick, and José Baselga
	JCO Jan 1 2004: 175–184. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Methadone Versus Morphine As a First-Line Strong Opioid for Cancer Pain: A Randomized, Double-Blind Study
	Eduardo Bruera, J. Lynn Palmer, Snezana Bosnjak, Maria Antonieta Rico, Jairo Moyano, Catherine Sweeney, Florian Strasser, Jie Willey, Mariela Bertolino, Clarissa Mathias, Odette Spruyt, and Michael J. Fisch
	JCO Jan 1 2004: 185–192. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Uncommon Presentations of Hodgkin's Disease: CASE 1. Hodgkin's Disease of the Jejunum

Peter B. Morgan, Ivan L. Kessel, Shu-Yuan Xiao, and Martin Colman

JCO Jan 1 2004: 193–195. [Full Text] [PDF]

Uncommon Presentations of Hodgkin's Disease: CASE 2. Hodgkin's Disease of the Nasopharynx

Sandra L. Hollander

JCO Jan 1 2004: 195–196. [Full Text] [PDF]

Uncommon Presentations of Hodgkin's Disease: CASE 3. Hodgkin's Disease: Rectal Presentation

Lijo Simpson, Samuel Taylor, and Agnes Piotrowski

JCO Jan 1 2004: 196–198. [Full Text] [PDF]

ART OF ONCOLOGY

Doctor, Does This Mean I'm Going to Starve to Death?

Melissa K. Whitworth, Andrea Whitfield, Søren Holm, John Shaffer, Wendy Makin, and Gordon C. Jayson

JCO Jan 1 2004: 199–201. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Peritoneal Carcinomatosis: What Can We Do About It?

Perry Shen, Edward A. Levine, and Brian W. Loggie

JCO Jan 1 2004: 202. [Full Text] [PDF]

In Reply:

Olivier Glehen and François Noël Gilly

JCO Jan 1 2004: 203. [Full Text] [PDF]

Problems With Nomenclature and Pharmacodynamics in Trophoblastic Disease

Ernest I. Kohorn

JCO Jan 1 2004: 203-a–204. [Full Text] [PDF]

In Reply:

Edward S. Newlands

JCO Jan 1 2004: 204. [Full Text] [PDF]

Fluoxetine Versus Placebo in Advanced Cancer Outpatients

Carol Alliot

JCO Jan 1 2004: 204-a–205. [Full Text] [PDF]

Prescribing Antidepressants to Advanced Cancer Patients With Mild Depressive Symptoms Is Not Justified

James C. Coyne, Steven C. Palmer, and Pamela J. Shapiro

JCO Jan 1 2004: 205–206. [Full Text] [PDF]

In Reply:

Michael J. Fisch, Jean L. Kristeller, Steven Passik, Patrick J. Loehrer, and Lawrence H. Einhorn

JCO Jan 1 2004: 206–208. [Full Text] [PDF]

Erratum

Erratum for Volume 18, pg. 2354

JCO Jan 1 2004: 209. [Full Text] [PDF]

Erratum for Volume 21, pg. 3651

JCO Jan 1 2004: 209-a. [Full Text] [PDF]

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