EDITORIALS

Molecular Prognostication for Soft Tissue Sarcomas: Are We Ready Yet?

Andre M. Oliveira and Christopher D.M. Fletcher

JCO Oct 15 2004: 4031–4034. First published on Sep 13 2004; 10.1200/JCO.2004.06.025. [Full Text] [PDF]

Can We Now Agree to Use the Same Definition to Measure Response According to CA-125?

Gordon J.S. Rustin

JCO Oct 15 2004: 4035–4036. First published on Sep 13 2004; 10.1200/JCO.2004.06.628. [Full Text] [PDF]

Cancer Screening: How Good Is Good Enough?

Martee L. Hensley and David R. Spriggs

JCO Oct 15 2004: 4037–4039. First published on Sep 20 2004; 10.1200/JCO.2004.06.129. [Full Text] [PDF]

ORIGINAL REPORTS
Sarcomas
	Histologic Grade, But Not SYT-SSX Fusion Type, Is an Important Prognostic Factor in Patients With Synovial Sarcoma: A Multicenter, Retrospective Analysis
	Louis Guillou, Jean Benhattar, Françoise Bonichon, Gabrielle Gallagher, Philippe Terrier, Edouard Stauffer, Nicolas de Saint Aubain Somerhausen, Jean-Jacques Michels, Gernot Jundt, Dominique Ranchère Vince, Sophia Taylor, Muriel Genevay, Françoise Collin, Martine Trassard, and Jean-Michel Coindre
	JCO Oct 15 2004: 4040–4050. First published on Sep 13 2004; 10.1200/JCO.2004.11.093. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Should CA-125 Response Criteria Be Preferred to Response Evaluation Criteria in Solid Tumors (RECIST) for Prognostication During Second-Line Chemotherapy of Ovarian Carcinoma?
	Bo Gronlund, Claus Høgdall, Jørgen Hilden, Svend A. Engelholm, Estrid V.S. Høgdall, and Heine H. Hansen
	JCO Oct 15 2004: 4051–4058. First published on Sep 13 2004; 10.1200/JCO.2004.10.028. [Abstract] [Full Text] [PDF]
	Preoperative Sensitivity and Specificity for Early-Stage Ovarian Cancer When Combining Cancer Antigen CA-125II, CA 15-3, CA 72-4, and Macrophage Colony-Stimulating Factor Using Mixtures of Multivariate Normal Distributions
	Steven J. Skates, Nora Horick, Yinhua Yu, Feng-Ji Xu, Andrew Berchuck, Laura J. Havrilesky, Henk W.A. de Bruijn, Ate G.J. van der Zee, Robert P. Woolas, Ian J. Jacobs, Zhen Zhang, and Robert C. Bast, Jr
	JCO Oct 15 2004: 4059–4066. First published on Sep 20 2004; 10.1200/JCO.2004.03.091. [Abstract] [Full Text] [PDF]

Breast Cancer
	Long-Term Follow-Up for Locally Advanced and Inflammatory Breast Cancer Patients Treated With Multimodality Therapy
	Jennifer A. Low, Arlene W. Berman, Seth M. Steinberg, David N. Danforth, Marc E. Lippman, and Sandra M. Swain
	JCO Oct 15 2004: 4067–4074. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Outcome of Treatment in Adults With Acute Lymphoblastic Leukemia: Analysis of the LALA-94 Trial
	Xavier Thomas, Jean-Michel Boiron, Françoise Huguet, Hervé Dombret, Ken Bradstock, Norbert Vey, Tibor Kovacsovics, André Delannoy, Nathalie Fegueux, Pierre Fenaux, Aspasia Stamatoullas, Jean-Paul Vernant, Olivier Tournilhac, Agnès Buzyn, Oumedaly Reman, Christiane Charrin, Claude Boucheix, Jean Gabert, Véronique Lhéritier, and Denis Fiere
	JCO Oct 15 2004: 4075–4086. First published on Sep 7 2004; 10.1200/JCO.2004.10.050. [Abstract] [Full Text] [PDF]
	Autologous Stem-Cell Transplantation Can Be Performed Safely Without the Use of Blood-Product Support
	Karen K. Ballen, Pamela S. Becker, Beow Yong Yeap, Barbara Matthews, David H. Henry, and Patricia A. Ford
	JCO Oct 15 2004: 4087–4094. First published on Sep 7 2004; 10.1200/JCO.2004.01.144. [Abstract] [Full Text] [PDF]
	Phase II Study of Denileukin Diftitox for Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
	Nam H. Dang, Fredrick B. Hagemeister, Barbara Pro, Peter McLaughlin, Jorge E. Romaguera, Dan Jones, Barry Samuels, Felipe Samaniego, Anas Younes, Michael Wang, Andre Goy, Maria A. Rodriguez, Pamela L. Walker, Yolanda Arredondo, Ann T. Tong, and Luis Fayad
	JCO Oct 15 2004: 4095–4102. First published on Sep 7 2004; 10.1200/JCO.2004.03.071. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Is Eligibility for a Chemotherapy Protocol a Good Prognostic Factor for Invasive Bladder Cancer After Radical Cystectomy?
	Stephan Madersbacher, George N. Thalmann, Johannes C. Fritsch, and Urs E. Studer
	JCO Oct 15 2004: 4103–4108. [Abstract] [Full Text] [PDF]
	Immediate Versus Deferred Hormonal Treatment for Patients With Prostate Cancer Who Are Not Suitable for Curative Local Treatment: Results of the Randomized Trial SAKK 08/88
	Urs E. Studer, Dieter Hauri, Silvia Hanselmann, Dominique Chollet, Hans-Jürg Leisinger, Thomas Gasser, Edgar Senn, Felix B. Trinkler, Reto M. Tscholl, George N. Thalmann, and Daniel Dietrich
	JCO Oct 15 2004: 4109–4118. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Response to Paclitaxel, Topotecan, and Topotecan-Cyclophosphamide in Children With Untreated Disseminated Neuroblastoma Treated in an Upfront Phase II Investigational Window: A Pediatric Oncology Group Study
	Cynthia S. Kretschmar, Morris Kletzel, Kevin Murray, Paul Thorner, Vijay Joshi, Robert Marcus, E. Ide Smith, Wendy B. London, and Robert Castleberry
	JCO Oct 15 2004: 4119–4126. [Abstract] [Full Text] [PDF]
	GABAergic System Gene Expression Predicts Clinical Outcome in Patients With Neuroblastoma
	Stephen S. Roberts, Motomi Mori, Patrick Pattee, Jodi Lapidus, Ravi Mathews, Jean P. O'Malley, Yi Ching Hsieh, Mark A. Turner, Zhaohong Wang, Qi Tian, Matthew J. Rodland, C. Patrick Reynolds, Robert C. Seeger, and Srinivasa R. Nagalla
	JCO Oct 15 2004: 4127–4134. [Abstract] [Full Text] [PDF]
	Midline Carcinoma of Children and Young Adults With NUT Rearrangement
	Christopher A. French, Jeffery L. Kutok, William C. Faquin, Jeffrey A. Toretsky, Cristina R. Antonescu, Constance A. Griffin, Vania Nose, Sara O. Vargas, Mary Moschovi, Fotini Tzortzatou-Stathopoulou, Isao Miyoshi, Antonio R. Perez-Atayde, Jon C. Aster, and Jonathan A. Fletcher
	JCO Oct 15 2004: 4135–4139. [Abstract] [Full Text] [PDF]
	Frequency and Heritability of WT1 Mutations in Nonsyndromic Wilms' Tumor Patients: A UK Children’s Cancer Study Group Study
	Suzanne E. Little, Sandra P. Hanks, Linda King-Underwood, Chris Jones, Elizabeth A. Rapley, Nazneen Rahman, and Kathy Pritchard-Jones
	JCO Oct 15 2004: 4140–4146. [Abstract] [Full Text] [PDF]

Diagnostics
	Clinical Decisions Associated With Positron Emission Tomography in a Prospective Cohort of Patients With Suspected or Known Cancer at One United States Center
	Bruce E. Hillner, Renuka Tunuguntla, and Melvin Fratkin
	JCO Oct 15 2004: 4147–4156. [Abstract] [Full Text] [PDF]

Lung Cancer
	Circulating Deoxyribonucleic Acid As Prognostic Marker in Non–Small-Cell Lung Cancer Patients Undergoing Chemotherapy
	Oliver Gautschi, Colette Bigosch, Barbara Huegli, Monika Jermann, Arthur Marx, Eveline Chassé, Daniel Ratschiller, Walter Weder, Markus Joerger, Daniel C. Betticher, Rolf A. Stahel, and Annemarie Ziegler
	JCO Oct 15 2004: 4157–4164. [Abstract] [Full Text] [PDF]
	Regulation of p27 by S-Phase Kinase-Associated Protein 2 Is Associated With Aggressiveness in Non–Small-Cell Lung Cancer
	Atsushi Osoegawa, Ichiro Yoshino, Shinji Tanaka, Kenji Sugio, Toshifumi Kameyama, Masafumi Yamaguchi, and Yoshihiko Maehara
	JCO Oct 15 2004: 4165–4173. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Web-Based Survey of Fertility Issues in Young Women With Breast Cancer
	Ann H. Partridge, Shari Gelber, Jeffrey Peppercorn, Ebonie Sampson, Katherine Knudsen, Marc Laufer, Randi Rosenberg, Michele Przypyszny, Alison Rein, and Eric P. Winer
	JCO Oct 15 2004: 4174–4183. [Abstract] [Full Text] [PDF]
	Health-Related Quality of Life and Psychosocial Status in Breast Cancer Prognosis: Analysis of Multiple Variables
	Pamela J. Goodwin, Marguerite Ennis, Louise J. Bordeleau, Kathleen I. Pritchard, Maureen E. Trudeau, Jarley Koo, and Nicky Hood
	JCO Oct 15 2004: 4184–4192. [Abstract] [Full Text] [PDF]
	Racial/Ethnic Differences in Functional Outcomes in the 5 Years After Diagnosis of Localized Prostate Cancer
	Terri Kang Johnson, Frank D. Gilliland, Richard M. Hoffman, Dennis Deapen, David F. Penson, Janet L. Stanford, Peter C. Albertsen, and Ann S. Hamilton
	JCO Oct 15 2004: 4193–4201. [Abstract] [Full Text] [PDF]
	Quality of Life After Transhiatal Compared With Extended Transthoracic Resection for Adenocarcinoma of the Esophagus
	A.G.E.M. de Boer, J.J.B. van Lanschot, J.W. van Sandick, J.B.F. Hulscher, P.F.M. Stalmeier, J.C.J.M. de Haes, H.W. Tilanus, H. Obertop, and M.A.G. Sprangers
	JCO Oct 15 2004: 4202–4208. [Abstract] [Full Text] [PDF]
	Suicide Risk in Cancer Patients From 1960 to 1999
	Erlend Hem, Jon H. Loge, Tor Haldorsen, and Øivind Ekeberg
	JCO Oct 15 2004: 4209–4216. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Putting the Rap on Akt
	James E. Thompson and Craig B. Thompson
	JCO Oct 15 2004: 4217–4226. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Unusual Sites of Hodgkin's Lymphoma: CASE 1. HIV-Associated Hodgkin's Lymphoma of the Stomach

John Doweiko, Bruce J. Dezube, and Liron Pantanowitz

JCO Oct 15 2004: 4227–4228. [Full Text] [PDF]

Unusual Sites of Hodgkin's Lymphoma: CASE 2. Hodgkin's Lymphoma of the CNS Masquerading As Meningioma

Bryan E. Figueroa, Jennifer R. Brown, Alessandra Nascimento, David C. Fisher, and Sagun Tuli

JCO Oct 15 2004: 4228–4230. [Full Text] [PDF]

Unusual Sites of Hodgkin's Lymphoma: CASE 3. Cholemic Nephrosis in Hodgkin's Lymphoma With Liver Involvement

Philipp Kiewe, Agnieszka Korfel, Christoph Loddenkemper, Lars Fischer, Kristoph Jahnke, Michael Notter, Felix Mühr-Wilkenshoff, Harald Stein, and Eckhard Thiel

JCO Oct 15 2004: 4230–4231. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

HER-2 Overexpression in Breast Tumors Lacking Gene Amplification

Steven M. Sorscher

JCO Oct 15 2004: 4232. [Full Text] [PDF]

In Reply:

Elena B. Elkin and Stuart J. Schnitt

JCO Oct 15 2004: 4232-a–4233. [Full Text] [PDF]

Long-Term Bisphosphonate Treatment of Bone Metastases From Renal Cell Carcinoma

M. Dror Michaelson, Daniel I. Rosenthal, and Matthew R. Smith

JCO Oct 15 2004: 4233–4234. [Full Text] [PDF]

Need for Further Information on Pemetrexed Study

Yossef Aelony

JCO Oct 15 2004: 4234–4235. [Full Text] [PDF]

In Reply:

Nicholas J. Vogelzang

JCO Oct 15 2004: 4235–4236. [Full Text] [PDF]

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