EDITORIALS

Combining the Anti-EGFR Agent Gefitinib With Chemotherapy in Non–Small-Cell Lung Cancer: How Do We Go From INTACT to Impact?

Jose Baselga

JCO Mar 1 2004: 759–761. [Full Text] [PDF]

Tumor Immunity in Small-Cell Lung Cancer

Robert Darnell

JCO Mar 1 2004: 762–764. [Full Text] [PDF]

Hypofractionated Radiotherapy for Advanced Non-Small-Cell Lung Cancer: Is the LINAC Half Full?

Jeffrey A. Bogart

JCO Mar 1 2004: 765–768. [Full Text] [PDF]

Cardiovascular Trials in Long-Term Survivors of Childhood Cancer

Steven E. Lipshultz and Steven D. Colan

JCO Mar 1 2004: 769–773. [Full Text] [PDF]

COMMENTS AND CONTROVERSIES

Physician-Nurse Collaboration in Research in the 21st Century

Arlene D. Houldin, Mary D. Naylor, and Daniel G. Haller

JCO Mar 1 2004: 774–776. [Full Text] [PDF]

ORIGINAL REPORTS
Lung Cancer
	Gefitinib in Combination With Gemcitabine and Cisplatin in Advanced Non–Small-Cell Lung Cancer: A Phase III Trial—INTACT 1
	Giuseppe Giaccone, Roy S. Herbst, Christian Manegold, Giorgio Scagliotti, Rafael Rosell, Vincent Miller, Ronald B. Natale, Joan H. Schiller, Joachim von Pawel, Anna Pluzanska, Ulrich Gatzemeier, John Grous, Judith S. Ochs, Steven D. Averbuch, Michael K. Wolf, Pamela Rennie, Abderrahim Fandi, and David H. Johnson
	JCO Mar 1 2004: 777–784. [Abstract] [Full Text] [PDF]
	Gefitinib in Combination With Paclitaxel and Carboplatin in Advanced Non–Small-Cell Lung Cancer: A Phase III Trial—INTACT 2
	Roy S. Herbst, Giuseppe Giaccone, Joan H. Schiller, Ronald B. Natale, Vincent Miller, Christian Manegold, Giorgio Scagliotti, Rafael Rosell, Ira Oliff, James A. Reeves, Michael K. Wolf, Annetta D. Krebs, Steven D. Averbuch, Judith S. Ochs, John Grous, Abderrahim Fandi, and David H. Johnson
	JCO Mar 1 2004: 785–794. [Abstract] [Full Text] [PDF]
	Hu and Voltage-Gated Calcium Channel (VGCC) Antibodies Related to the Prognosis of Small-Cell Lung Cancer
	S.E. Monstad, L. Drivsholm, A. Storstein, J.H. Aarseth, M. Haugen, B. Lang, A. Vincent, and C.A. Vedeler
	JCO Mar 1 2004: 795–800. [Abstract] [Full Text] [PDF]
	Hypofractionated Palliative Radiotherapy (17 Gy per two fractions) in Advanced Non–Small-Cell Lung Carcinoma Is Comparable to Standard Fractionation for Symptom Control and Survival: A National Phase III Trial
	Stein Sundstrøm, Roy Bremnes, Ulf Aasebø, Steinar Aamdal, Reidulv Hatlevoll, Paal Brunsvig, Dag Clement Johannessen, Olbjørn Klepp, Peter M. Fayers, and Stein Kaasa
	JCO Mar 1 2004: 801–810. [Abstract] [Full Text] [PDF]
	Prognostic Model of Pulmonary Adenocarcinoma by Expression Profiling of Eight Genes As Determined by Quantitative Real-Time Reverse Transcriptase Polymerase Chain Reaction
	Hideki Endoh, Shuta Tomida, Yasushi Yatabe, Hiroyuki Konishi, Hirotaka Osada, Kohei Tajima, Hiroyuki Kuwano, Takashi Takahashi, and Tetsuya Mitsudomi
	JCO Mar 1 2004: 811–819. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Enalapril to Prevent Cardiac Function Decline in Long-Term Survivors of Pediatric Cancer Exposed to Anthracyclines
	Jeffrey H. Silber, Avital Cnaan, Bernard J. Clark, Stephen M. Paridon, Alvin J. Chin, Jack Rychik, Alexa N. Hogarty, Mitchell I. Cohen, Gerald Barber, Monika Rutkowski, Thomas R. Kimball, Cynthia Delaat, Laurel J. Steinherz, and Huaqing Zhao
	JCO Mar 1 2004: 820–828. [Abstract] [Full Text] [PDF]
	Phase I and Pharmacokinetic Study of Topotecan Administered Orally Once Daily for 5 Days for 2 Consecutive Weeks to Pediatric Patients With Refractory Solid Tumors
	Najat C. Daw, Victor M. Santana, Lisa C. Iacono, Wayne L. Furman, Dana R. Hawkins, Peter J. Houghton, J. Carl Panetta, Amar J. Gajjar, and Clinton F. Stewart
	JCO Mar 1 2004: 829–837. [Abstract] [Full Text] [PDF]
	Clinical and Outcome Characteristics of Children With Adrenocortical Tumors: A Report From the International Pediatric Adrenocortical Tumor Registry
	E. Michalkiewicz, R. Sandrini, B. Figueiredo, E.C.M. Miranda, E. Caran, A.G. Oliveira-Filho, R. Marques, M.A.D. Pianovski, L. Lacerda, L.M. Cristofani, J. Jenkins, C. Rodriguez-Galindo, and R.C. Ribeiro
	JCO Mar 1 2004: 838–845. [Abstract] [Full Text] [PDF]

Neurooncology
	Primary Chemotherapy for Intracranial Nongerminomatous Germ Cell Tumors: Results of the Second International CNS Germ Cell Study Group Protocol
	Stewart J Kellie, Hayden Boyce, Ira J Dunkel, Blanca Diez, Marc Rosenblum, Lynette Brualdi, and Jonathan L Finlay
	JCO Mar 1 2004: 846–853. [Abstract] [Full Text] [PDF]

Breast Cancer
	HER-2 Testing and Trastuzumab Therapy for Metastatic Breast Cancer: A Cost-Effectiveness Analysis
	Elena B. Elkin, Milton C. Weinstein, Eric P. Winer, Karen M. Kuntz, Stuart J. Schnitt, and Jane C. Weeks
	JCO Mar 1 2004: 854–863. [Abstract] [Full Text] [PDF]
	Activity and Safety of the Antiestrogen EM-800, the Orally Active Precursor of Acolbifene, in Tamoxifen-Resistant Breast Cancer
	Fernand Labrie, Pierre Champagne, Claude Labrie, Jean Roy, Jacques Laverdière, Louise Provencher, Martin Potvin, Yvan Drolet, Michael Pollak, Lawrence Panasci, Bernard L'Espérance, Jean Dufresne, Jean Latreille, Jean Robert, Benoît Samson, Jacques Jolivet, Louise Yelle, Lionel Cusan, Pierre Diamond, and Bernard Candas
	JCO Mar 1 2004: 864–871. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Pelvic Irradiation With Concurrent Chemotherapy Versus Pelvic and Para-Aortic Irradiation for High-Risk Cervical Cancer: An Update of Radiation Therapy Oncology Group Trial (RTOG) 90-01
	Patricia J. Eifel, Kathryn Winter, Mitchell Morris, Charles Levenback, Perry W. Grigsby, Jay Cooper, Marvin Rotman, David Gershenson, and David G. Mutch
	JCO Mar 1 2004: 872–880. [Abstract] [Full Text] [PDF]
	Predictors of Sexual Functioning in Ovarian Cancer Patients
	Cindy L. Carmack Taylor, Karen Basen-Engquist, Eileen H. Shinn, and Diane C. Bodurka
	JCO Mar 1 2004: 881–889. [Abstract] [Full Text] [PDF]

Sarcomas
	Phase II Study of Ecteinascidin-743 in Advanced Pretreated Soft Tissue Sarcoma Patients
	A. Yovine, M. Riofrio, J.Y. Blay, E. Brain, J. Alexandre, C. Kahatt, A. Taamma, J. Jimeno, C. Martin, Y. Salhi, E. Cvitkovic, and J.L. Misset
	JCO Mar 1 2004: 890–899. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Time Course of Tumor Metabolic Activity During Chemoradiotherapy of Esophageal Squamous Cell Carcinoma and Response to Treatment
	Hinrich A. Wieder, Björn L.D.M. Brücher, Frank Zimmermann, Karen Becker, Florian Lordick, Ambros Beer, Markus Schwaiger, Ulrich Fink, Jörg Rüdiger Siewert, Hubert J. Stein, and Wolfgang A. Weber
	JCO Mar 1 2004: 900–908. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Randomized Phase II Study of Multiple Dose Levels of CCI-779, a Novel Mammalian Target of Rapamycin Kinase Inhibitor, in Patients With Advanced Refractory Renal Cell Carcinoma
	Michael B. Atkins, Manuel Hidalgo, Walter M. Stadler, Theodore F. Logan, Janice P. Dutcher, Gary R. Hudes, Young Park, Song-Heng Liou, Bonnie Marshall, Joseph P. Boni, Gary Dukart, and Matthew L. Sherman
	JCO Mar 1 2004: 909–918. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Prevalence and Predictors of Psychological Distress Among Women With Ovarian Cancer
	Tina R. Norton, Sharon L. Manne, Stephen Rubin, John Carlson, Enrique Hernandez, Mitchell I. Edelson, Norman Rosenblum, David Warshal, and Cynthia Bergman
	JCO Mar 1 2004: 919–926. [Abstract] [Full Text] [PDF]
	Lamivudine for the Prevention of Hepatitis B Virus Reactivation in Hepatitis B s-Antigen Seropositive Cancer Patients Undergoing Cytotoxic Chemotherapy
	Winnie Yeo, Paul K.S. Chan, Wing M. Ho, Benny Zee, Kwok C. Lam, Kenny I.K. Lei, Anthony T.C. Chan, Tony S.K. Mok, Jam J. Lee, Thomas W.T. Leung, Sheng Zhong, and Philip J. Johnson
	JCO Mar 1 2004: 927–934. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Pharmacokinetics and Pharmacodynamics of Imatinib in a Phase I Trial With Chronic Myeloid Leukemia Patients
	Bin Peng, Michael Hayes, Debra Resta, Amy Racine-Poon, Brian J. Druker, Moshe Talpaz, Charles L. Sawyers, Marianne Rosamilia, John Ford, Peter Lloyd, and Renaud Capdeville
	JCO Mar 1 2004: 935–942. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Short-Term Impact of Cancer Prevention and Screening Activities on Quality of Life
	Jennifer Cullen, Marc D. Schwartz, William F. Lawrence, Joe V. Selby, and Jeanne S. Mandelblatt
	JCO Mar 1 2004: 943–952. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Difficult Diagnostic and Therapeutic Cases: CASE 1. True Thymic Hyperplasia in a Patient Treated for T-Cell Lymphoma

Stefano Ascani, Philip Went, Anna Marina Liberati, Pier Paolo Piccaluga, Pier Luigi Zinzani, and Stefano A. Pileri

JCO Mar 1 2004: 953–954. [Full Text] [PDF]

Difficult Diagnostic and Therapeutic Cases: CASE 2. Thymoma and Tumor Lysis Syndrome in an Adolescent

Angela D. Trobaugh-Lotrario, Xiayuan Liang, Joseph S. Janik, Mark A. Lovell, and Lorrie F. Odom

JCO Mar 1 2004: 955–957. [Full Text] [PDF]

Difficult Diagnostic and Therapeutic Cases: CASE 3. Presentation of Prostate Cancer With Cervical Adenopathy

S. Gaur, L.S. Aish, and T.H. Oo

JCO Mar 1 2004: 957–958. [Full Text] [PDF]

ART OF ONCOLOGY

On the Death of a Spouse: Reflections of a Medical Oncologist

Peter A. Beatty

JCO Mar 1 2004: 959–960. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Validation of the 2001 St Gallen Risk Categories for Node-Negative Breast Cancer Using a Database From the Spanish Breast Cancer Research Group (GEICAM)

R. Colomer, G. Viñas, M. Beltran, A. Izquierdo, A. Lluch, A. Llombart-Cussac, E. Alba, B. Munárriz, and M. Martín

JCO Mar 1 2004: 961–962. [Full Text] [PDF]

No Rational Theory for Drug Pricing

Michael C. Cox, William D. Figg, and Paul W. Thurman

JCO Mar 1 2004: 962–963. [Full Text] [PDF]

Is the In Vitro Drug Resistance Profile the Strongest Prognostic Factor in Childhood Acute Lymphoblastic Leukemia?

Jan Styczynski and Mariusz Wysocki

JCO Mar 1 2004: 963–964. [Full Text] [PDF]

The Vincotube System: A Design Solution to Prevent the Accidental Administration of Intrathecal Vinca Alkaloids

Carlo Palmieri, Neil Barron, and David M. Vigushin

JCO Mar 1 2004: 965. [Full Text] [PDF]

In Reply:

Angelou Stefanou and Michael Dooley

JCO Mar 1 2004: 965-a–966. [Full Text] [PDF]

The Measurement of Cognitive Functioning in Low-Grade Glioma Patients After Radiotherapy

Martin Klein and Jan J. Heimans

JCO Mar 1 2004: 966–967. [Full Text] [PDF]

In Reply:

Paul Brown and Jan Buckner

JCO Mar 1 2004: 967–968. [Full Text] [PDF]

Erratum

ERRATUM

JCO Mar 1 2004: 969. [Full Text] [PDF]

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