EDITORIALS

Lymphadenectomy in Apparent Early-Stage Endometrial Carcinoma: Do Numbers Count?

Carien L. Creutzberg

JCO Jun 1 2005: 3653–3655. First published on Feb 28 2005; 10.1200/JCO.2005.11.947. [Full Text] [PDF]

HER2 or Not HER2: That Is the Question

Harold J. Burstein and Eric P. Winer

JCO Jun 1 2005: 3656–3659. First published on Feb 28 2005; 10.1200/JCO.2005.10.910. [Full Text] [PDF]

Bevacizumab Plus Fluorouracil: The Value of Being Part of a Developing Story

Alberto Sobrero and Paolo Bruzzi

JCO Jun 1 2005: 3660–3662. First published on Feb 28 2005; 10.1200/JCO.2005.11.941. [Full Text] [PDF]

Hidden by HIPAA: The Costs of Cure

Derek Raghavan

JCO Jun 1 2005: 3663–3665. First published on Feb 28 2005; 10.1200/JCO.2005.11.951. [Full Text] [PDF]

COMMENTS AND CONTROVERSIES

Serving Interests in Hematologic Malignancies in the Journal of Clinical Oncology

Bruce D. Cheson, Daniel Haller, and Sandra J. Horning

JCO Jun 1 2005: 3666–3667. [Full Text] [PDF]

ORIGINAL REPORTS
Gynecologic Cancer
	Retrospective Analysis of Selective Lymphadenectomy in Apparent Early-Stage Endometrial Cancer
	Janiel M. Cragun, Laura J. Havrilesky, Brian Calingaert, Ingrid Synan, Angeles Alvarez Secord, John T. Soper, Daniel L. Clarke-Pearson, and Andrew Berchuck
	JCO Jun 1 2005: 3668–3675. First published on Feb 28 2005; 10.1200/JCO.2005.04.144. [Abstract] [Full Text] [PDF]

Breast Cancer
	Significantly Higher Pathologic Complete Remission Rate After Neoadjuvant Therapy With Trastuzumab, Paclitaxel, and Epirubicin Chemotherapy: Results of a Randomized Trial in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer
	Aman U. Buzdar, Nuhad K. Ibrahim, Deborah Francis, Daniel J. Booser, Eva S. Thomas, Richard L. Theriault, Lajos Pusztai, Marjorie C. Green, Banu K. Arun, Sharon H. Giordano, Massimo Cristofanilli, Debra K. Frye, Terry L. Smith, Kelly K. Hunt, Sonja E. Singletary, Aysegul A. Sahin, Michael S. Ewer, Thomas A. Buchholz, Donald Berry, and Gabriel N. Hortobagyi
	JCO Jun 1 2005: 3676–3685. First published on Feb 28 2005; 10.1200/JCO.2005.07.032. [Abstract] [Full Text] [PDF]
	Paclitaxel After Doxorubicin Plus Cyclophosphamide As Adjuvant Chemotherapy for Node-Positive Breast Cancer: Results From NSABP B-28
	Eleftherios P. Mamounas, John Bryant, Barry Lembersky, Louis Fehrenbacher, Scot M. Sedlacek, Bernard Fisher, D. Lawrence Wickerham, Greg Yothers, Atilla Soran, and Norman Wolmark
	JCO Jun 1 2005: 3686–3696. First published on May 16 2005; 10.1200/JCO.2005.10.517. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Addition of Bevacizumab to Bolus Fluorouracil and Leucovorin in First-Line Metastatic Colorectal Cancer: Results of a Randomized Phase II Trial
	Fairooz F. Kabbinavar, Joseph Schulz, Michael McCleod, Taral Patel, John T. Hamm, J. Randolph Hecht, Robert Mass, Brent Perrou, Betty Nelson, and William F. Novotny
	JCO Jun 1 2005: 3697–3705. First published on Feb 28 2005; 10.1200/JCO.2005.05.112. [Abstract] [Full Text] [PDF]
	Combined Analysis of Efficacy: The Addition of Bevacizumab to Fluorouracil/Leucovorin Improves Survival for Patients With Metastatic Colorectal Cancer
	Fairooz F. Kabbinavar, Julie Hambleton, Robert D. Mass, Herbert I. Hurwitz, Emily Bergsland, and Somnath Sarkar
	JCO Jun 1 2005: 3706–3712. First published on May 2 2005; 10.1200/JCO.2005.00.232. [Abstract] [Full Text] [PDF]
	2-(18F)-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography Detects Clinical Relevant Adenomas of the Colon: A Prospective Study
	Mariëtte C.A. van Kouwen, Fokko M. Nagengast, Jan B.M.J. Jansen, Wim J.G. Oyen, and Joost P.H. Drenth
	JCO Jun 1 2005: 3713–3717. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	The Metabolic Syndrome and Disturbances in Hormone Levels in Long-Term Survivors of Disseminated Testicular Cancer
	Janine Nuver, Andries J. Smit, Bruce H.R. Wolffenbuttel, Wim J. Sluiter, Harald J. Hoekstra, Dirk T. Sleijfer, and Jourik A. Gietema
	JCO Jun 1 2005: 3718–3725. First published on Feb 28 2005; 10.1200/JCO.2005.02.176. [Abstract] [Full Text] [PDF]
	Successful Implementation of the Randomized Discontinuation Trial Design: An Application to the Study of the Putative Antiangiogenic Agent Carboxyaminoimidazole in Renal Cell Carcinoma—CALGB 69901
	Walter M. Stadler, Gary Rosner, Eric Small, Donna Hollis, Brian Rini, S. Donald Zaentz, John Mahoney, and Mark J. Ratain
	JCO Jun 1 2005: 3726–3732. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Nonmelanoma Skin Cancer in Survivors of Childhood and Adolescent Cancer: A Report From the Childhood Cancer Survivor Study
	Joanna L. Perkins, Yan Liu, Pauline A. Mitby, Joseph P. Neglia, Sue Hammond, Marilyn Stovall, Anna T. Meadows, Ray Hutchinson, ZoAnn E. Dreyer, Leslie L. Robison, and Ann C. Mertens
	JCO Jun 1 2005: 3733–3741. [Abstract] [Full Text] [PDF]
	Childhood Cancer Survival Trends in Europe: A EUROCARE Working Group Study
	Gemma Gatta, Riccardo Capocaccia, Charles Stiller, Peter Kaatsch, Franco Berrino, Monica Terenziani, and the EUROCARE Working Group
	JCO Jun 1 2005: 3742–3751. [Abstract] [Full Text] [PDF]

Lung Cancer
	Randomized Phase III Intergroup Trial of Etoposide and Cisplatin With or Without Paclitaxel and Granulocyte Colony-Stimulating Factor in Patients With Extensive-Stage Small-Cell Lung Cancer: Cancer and Leukemia Group B Trial 9732
	Harvey B. Niell, James E. Herndon, II, Antonius A. Miller, Dorothy M. Watson, Alan B. Sandler, Karen Kelly, Randolph S. Marks, Micheal C. Perry, Rafat H. Ansari, Grefory Otterson, John Ellerton, Everett E. Vokes, and Mark R. Green
	JCO Jun 1 2005: 3752–3759. [Abstract] [Full Text] [PDF]
	Phase III Study of the Eastern Cooperative Oncology Group (ECOG 2597): Induction Chemotherapy Followed by Either Standard Thoracic Radiotherapy or Hyperfractionated Accelerated Radiotherapy for Patients With Unresectable Stage IIIA and B Non–Small-Cell Lung Cancer
	Chandra P. Belani, Wei Wang, David H. Johnson, Henry Wagner, Joan Schiller, Michael Veeder, and Minesh Mehta
	JCO Jun 1 2005: 3760–3767. First published on Apr 18 2005; 10.1200/JCO.2005.09.108. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Gastric Mucosa-Associated Lymphoid Tissue Lymphoma Detected by Clonotypic Polymerase Chain Reaction Despite Continuous Pathologic Remission Induced by Involved-Field Radiotherapy
	Ariela Noy, Joachim Yahalom, Leah Zaretsky, Ian Brett, and Andrew D. Zelenetz
	JCO Jun 1 2005: 3768–3772. [Abstract] [Full Text] [PDF]
	Expression of bcl-2 in Classical Hodgkin's Lymphoma: An Independent Predictor of Poor Outcome
	Stephen J. Sup, Carlos A. Alemañy, Brad Pohlman, Paul Elson, Serena Malhi, Snehal Thakkar, Roxanne Steinle, and Eric D. Hsi
	JCO Jun 1 2005: 3773–3779. First published on Apr 4 2005; 10.1200/JCO.2005.04.358. [Abstract] [Full Text] [PDF]
	Evidence for Distinct Pathomechanisms in Genetic Subgroups of Chronic Lymphocytic Leukemia Revealed by Quantitative Expression Analysis of Cell Cycle, Activation, and Apoptosis-Associated Genes
	Dirk L. Kienle, Christian Korz, Beate Hosch, Axel Benner, Daniel Mertens, Annett Habermann, Alexander Kröber, Ulrich Jäger, Peter Lichter, Hartmut Döhner, and Stephan Stilgenbauer
	JCO Jun 1 2005: 3780–3792. First published on May 2 2005; 10.1200/JCO.2005.02.568. [Abstract] [Full Text] [PDF]
	Impact of Three Courses of Intensified CHOP Prior to High-Dose Sequential Therapy Followed by Autologous Stem-Cell Transplantation As First-Line Treatment in Poor-Risk, Aggressive Non-Hodgkin's Lymphoma: Comparative Analysis of Dutch-Belgian Hemato-Oncology Cooperative Group Studies 27 and 40
	Gustaaf W. van Imhoff, Bronno van der Holt, Marius A. MacKenzie, Mars B. van't Veer, Pierre W. Wijermans, Gerrit J. Ossenkoppele, Harry C. Schouten, Pieter Sonneveld, Monique M.C. Steijaert, Philip M. Kluin, Hanneke C. Kluin-Nelemans, and Leo F. Verdonck
	JCO Jun 1 2005: 3793–3801. First published on Apr 4 2005; 10.1200/JCO.2005.07.039. [Abstract] [Full Text] [PDF]

Clinical Trials
	Analysis of Treatment Practices for Elderly Cancer Patients in Ontario, Canada
	Carol Townsley, Gregory R. Pond, Brenda Peloza, Joanne Kok, Kendra Naidoo, Darlene Dale, Carole Herbert, Eric Holowaty, Sharon Straus, and Lillian L. Siu
	JCO Jun 1 2005: 3802–3810. [Abstract] [Full Text] [PDF]
	Impact of Managed Care on Cancer Trial Enrollment
	C.P. Gross and H.M. Krumholz
	JCO Jun 1 2005: 3811–3818. [Abstract] [Full Text] [PDF]

Bone Marrow Transplantation
	Hematopoietic Cell Transplantation After Nonmyeloablative Conditioning for Advanced Chronic Lymphocytic Leukemia
	Mohamed L. Sorror, Michael B. Maris, Brenda M. Sandmaier, Barry E. Storer, Monic J. Stuart, Ute Hegenbart, Edward Agura, Thomas R. Chauncey, Jose Leis, Michael Pulsipher, Peter McSweeney, Jerald P. Radich, Christopher Bredeson, Benedetto Bruno, Amelia Langston, Michael R. Loken, Haifa Al-Ali, Karl G. Blume, Rainer Storb, and David G. Maloney
	JCO Jun 1 2005: 3819–3829. First published on Apr 4 2005; 10.1200/JCO.2005.04.569. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Physical Exercise in Cancer Patients During and After Medical Treatment: A Systematic Review of Randomized and Controlled Clinical Trials
	Ruud Knols, Neil K. Aaronson, Daniel Uebelhart, Jaap Fransen, and Geert Aufdemkampe
	JCO Jun 1 2005: 3830–3842. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Conditions Suggesting Lymphoma: CASE 1. Lymphomatoid Papulosis

Bradley A. Sachs, Nasir Shahab, Paul A. Kaplan, Donald C. Doll, and Syed Haider

JCO Jun 1 2005: 3843–3844. [Full Text] [PDF]

Conditions Suggesting Lymphoma: CASE 2. Mediastinal Liposarcoma in a Patient With Previous Testicular Cancer

Michele Caraglia, Liliana Montella, Raffaele Addeo, Raffaele Costanzo, Vincenzo Faiola, Salvatore Del Prete, Feliciano Baldi, Alfonso Baldi, Alberto Abbruzzese, and Marco Alloisio

JCO Jun 1 2005: 3844–3846. [Full Text] [PDF]

Conditions Suggesting Lymphoma: CASE 3. Primary Synovial Lymphoma With Osteoclast-Like Giant Cells Presenting As a Tenosynovial Giant-Cell Tumor

Akira Ogose, Hiroyuki Kawashima, Tetsuo Hotta, Naoto Endo, Hajime Umezu, and Nobuhiko Nomoto

JCO Jun 1 2005: 3847–3848. [Full Text] [PDF]

ART OF ONCOLOGY

As-Needed Morphine: Yes, but at What Dose and at What Interval?

Matthew Ryan, Timothy J. Moynihan, and Charles L. Loprinzi

JCO Jun 1 2005: 3849–3852. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Minimal Residual Tumor Masses in Nonseminomatous Testicular Cancer: Surgery or Surveillance?

Yvonne Vergouwe and Ewout W. Steyerberg

JCO Jun 1 2005: 3853. [Full Text] [PDF]

Eicosapentaenoic Acid: The Answers Are Not All In

Mellar P. Davis

JCO Jun 1 2005: 3854. [Full Text] [PDF]

In Reply:

Aminah Jatoi, Charles L. Loprinzi, Kendrith Rowland, and Shaker Dakhil

JCO Jun 1 2005: 3854-a–3855. [Full Text] [PDF]

Elimination of Imatinib Mesylate and Its Metabolite N-Desmethyl-Imatinib

Martin Bornhäuser, Stefan Pursche, Malte Bonin, Jens Freiberg-Richter, Andreas Jenke, Thomas Illmer, Gerhard Ehninger, and Eberhard Schleyer

JCO Jun 1 2005: 3855–3856. [Full Text] [PDF]

In Reply:

Bin Peng and Renaud Capdeville

JCO Jun 1 2005: 3857–3858. [Full Text] [PDF]

Further Evidence on the Safety and Success of Ovarian Stimulation With Letrozole and Tamoxifen in Breast Cancer Patients Undergoing In Vitro Fertilization to Cryopreserve Their Embryos for Fertility Preservation

Kutluk Oktay

JCO Jun 1 2005: 3858–3859. First published on May 23 2005; 10.1200/JCO.2005.04.011. [Full Text] [PDF]

Inflammatory Breast Cancer and High-Dose Chemotherapy: Back to the Past

Ana Maria Gonzalez-Angulo, Paolo Morandi, and Massimo Cristofanilli

JCO Jun 1 2005: 3859–3860. [Full Text] [PDF]

In Reply:

George Somlo

JCO Jun 1 2005: 3860–3862. [Full Text] [PDF]

Controversy in Folinic Acid Administration After Fluorouracil

Yesim Yildirim, Zafer Akcali, and Ozgur Ozyilkan

JCO Jun 1 2005: 3862. [Full Text] [PDF]

In Reply:

Halfdan Sørbye and Bengt Glimelius

JCO Jun 1 2005: 3862-a–3863. [Full Text] [PDF]

Pitfalls in the Use of RT-PCR As a Prognostic Indicator in Melanoma

Robert A. Wascher

JCO Jun 1 2005: 3863–3864. [Full Text] [PDF]

In Reply:

Udai S. Kammula and Daniel G. Coit

JCO Jun 1 2005: 3864–3865. [Full Text] [PDF]

Gefitinib Has the Potential of Activating Cell Immunity Against Malignant Cells

Shigenori Kanazawa, Mikiko Muramatsu, Yoshimi Kinoshita, Kazuyuki Yamaguchi, and Shosaku Nomura

JCO Jun 1 2005: 3865–3866. [Full Text] [PDF]

In Reply:

Nicola Normanno and Antonella De Luca

JCO Jun 1 2005: 3866–3867. [Full Text] [PDF]

Progesterone Receptor Testing: Not the Right Time to Be Buried

M. Colozza, D. Larsimont, and M.J. Piccart

JCO Jun 1 2005: 3867–3868. [Full Text] [PDF]

It Is Not Time to Stop Progesterone Receptor Testing in Breast Cancer

R. Colomer, M. Beltran, J. Dorcas, H. Cortes-Funes, J. Hornedo, V. Valentin, C. Vargas, C. Mendiola, and E. Ciruelos

JCO Jun 1 2005: 3868–3869. [Full Text] [PDF]

In Reply:

Ivo A. Olivotto, Pauline T. Truong, Vanessa Bernstein, and James K. Kelly

JCO Jun 1 2005: 3869–3870. [Full Text] [PDF]

Preoperative Radiochemotherapy in Gastric Cancer: Another Ongoing Shift From Adjuvant to Neoadjuvant?

Abdelkarim S. Allal

JCO Jun 1 2005: 3870. [Full Text] [PDF]

In Reply:

Jaffer A. Ajani

JCO Jun 1 2005: 3870-a–3871. [Full Text] [PDF]

Clinical Use of AMD3100 to Mobilize CD34+ Cells in Patients Affected by Non-Hodgkin's Lymphoma or Multiple Myeloma

Giovanni Grignani, Eliana Perissinotto, Giuliana Cavalloni, Fabrizio Carnevale Schianca, and Massimo Aglietta

JCO Jun 1 2005: 3871–3872. [Full Text] [PDF]

In Reply:

Steven Devine, Yair Gazitt, and Gary Calandra

JCO Jun 1 2005: 3872–3873. [Full Text] [PDF]

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