EDITORIALS

Selecting Patients for Epidermal Growth Factor Receptor Inhibitor Treatment: A FISH Story or a Tale of Mutations?

Bruce E. Johnson and Pasi A. Jänne

JCO Oct 1 2005: 6813–6816. First published on Sep 6 2005; 10.1200/JCO.2005.97.008. [Full Text] [PDF]

Quality or Quantity in the Management of Hereditary Ovarian Cancer Risk: Is It Really a Trade-Off?

Serena Masciari and Judy E. Garber

JCO Oct 1 2005: 6817–6819. First published on Sep 12 2005; 10.1200/JCO.2005.96.009. [Full Text] [PDF]

Who's Taking Care of the Caregiver?

Ann O'Mara

JCO Oct 1 2005: 6820–6821. First published on Sep 6 2005; 10.1200/JCO.2005.96.008. [Full Text] [PDF]

Acting on Imperfect Evidence: How Much Regret Are We Ready to Accept?

Benjamin Djulbegovic, Andrew Frohlich, and Charles L. Bennett

JCO Oct 1 2005: 6822–6825. First published on Sep 6 2005; 10.1200/JCO.2005.06.007. [Full Text] [PDF]

Just When You Thought the Fluorouracil Debate Was Over: S-1 and Gastric Cancer

David Ilson

JCO Oct 1 2005: 6826–6828. First published on Sep 6 2005; 10.1200/JCO.2005.06.006. [Full Text] [PDF]

ORIGINAL REPORTS
Lung Cancer
	Epidermal Growth Factor Receptor Gene Mutations and Increased Copy Numbers Predict Gefitinib Sensitivity in Patients With Recurrent Non–Small-Cell Lung Cancer
	Toshimi Takano, Yuichiro Ohe, Hiromi Sakamoto, Koji Tsuta, Yoshihiro Matsuno, Ukihide Tateishi, Seiichiro Yamamoto, Hiroshi Nokihara, Noboru Yamamoto, Ikuo Sekine, Hideo Kunitoh, Tatsuhiro Shibata, Tokuki Sakiyama, Teruhiko Yoshida, and Tomohide Tamura
	JCO Oct 1 2005: 6829–6837. First published on Jul 5 2005; 10.1200/JCO.2005.01.0793. [Abstract] [Full Text] [PDF]
	Increased Epidermal Growth Factor Receptor Gene Copy Number Detected by Fluorescence In Situ Hybridization Associates With Increased Sensitivity to Gefitinib in Patients With Bronchioloalveolar Carcinoma Subtypes: A Southwest Oncology Group Study
	Fred R. Hirsch, Marileila Varella-Garcia, Jason McCoy, Howard West, Ana Carolina Xavier, Paul Gumerlock, Paul A. Bunn, Jr, Wilbur A. Franklin, John Crowley, and David R. Gandara
	JCO Oct 1 2005: 6838–6845. First published on Jul 5 2005; 10.1200/JCO.2005.01.2823. [Abstract] [Full Text] [PDF]
	Etiology of Solitary Extrapulmonary Positron Emission Tomography and Computed Tomography Findings in Patients With Lung Cancer
	Didier Lardinois, Walter Weder, Marina Roudas, Gustav K. von Schulthess, Michaela Tutic, Holger Moch, Rolf A. Stahel, and Hans C. Steinert
	JCO Oct 1 2005: 6846–6853. [Abstract] [Full Text] [PDF]
	Phase III Study of Adjuvant Vaccination With Bec2/Bacille Calmette-Guerin in Responding Patients With Limited-Disease Small-Cell Lung Cancer (European Organisation for Research and Treatment of Cancer 08971-08971B; Silva Study)
	Giuseppe Giaccone, Channa Debruyne, Enriqueta Felip, Paul B. Chapman, Stefan C. Grant, Michael Millward, Luc Thiberville, Giannicola D'addario, Corneel Coens, Lisa S. Rome, Petr Zatloukal, Oriol Masso, and Catherine Legrand
	JCO Oct 1 2005: 6854–6864. [Abstract] [Full Text] [PDF]
	Pretreatment Quality of Life and Functional Status Assessment Significantly Predict Survival of Elderly Patients With Advanced Non—Small-Cell Lung Cancer Receiving Chemotherapy: A Prognostic Analysis of the Multicenter Italian Lung Cancer in the Elderly Study
	Paolo Maione, Francesco Perrone, Ciro Gallo, Luigi Manzione, FrancoVito Piantedosi, Santi Barbera, Silvio Cigolari, Francesco Rosetti, Elena Piazza, Sergio Federico Robbiati, Oscar Bertetto, Silvia Novello, Maria Rita Migliorino, Adolfo Favaretto, Mario Spatafora, Francesco Ferraù, Luciano Frontini, Alessandra Bearz, Lazzaro Repetto, and Cesare Gridelli
	JCO Oct 1 2005: 6865–6872. [Abstract] [Full Text] [PDF]
	Concurrent Hyperfractionated Radiotherapy and Low-Dose Daily Carboplatin/Paclitaxel in Patients With Early-Stage (I/II) Non–Small-Cell Lung Cancer: Long-Term Results of a Phase II Study
	Branislav Jeremic, Biljana Milicic, Ljubisa Acimovic, and Slobodan Milisavljevic
	JCO Oct 1 2005: 6873–6880. [Abstract] [Full Text] [PDF]
	Randomized Phase III Study of Cisplatin With or Without Raltitrexed in Patients With Malignant Pleural Mesothelioma: An Intergroup Study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Institute of Canada
	Jan P. van Meerbeeck, Rabab Gaafar, Christian Manegold, Rob J. Van Klaveren, Eric A. Van Marck, Mark Vincent, Catherine Legrand, Andrew Bottomley, Channa Debruyne, and Giuseppe Giaccone
	JCO Oct 1 2005: 6881–6889. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Quality-of-Life Effects of Prophylactic Salpingo-Oophorectomy Versus Gynecologic Screening Among Women at Increased Risk of Hereditary Ovarian Cancer
	Joanna B. Madalinska, Judith Hollenstein, Eveline Bleiker, Marc van Beurden, Heiddis B. Valdimarsdottir, Leon F. Massuger, Katja N. Gaarenstroom, Marian J.E. Mourits, René H.M. Verheijen, Eleonora B.L. van Dorst, Hans van der Putten, Ko van der Velden, Henk Boonstra, and Neil K. Aaronson
	JCO Oct 1 2005: 6890–6898. First published on Aug 29 2005; 10.1200/JCO.2005.02.626. [Abstract] [Full Text] [PDF]
	Psychiatric Disorders and Mental Health Service Use Among Caregivers of Advanced Cancer Patients
	Lauren C. Vanderwerker, Rachel E. Laff, Nina S. Kadan-Lottick, Suzanne McColl, and Holly G. Prigerson
	JCO Oct 1 2005: 6899–6907. First published on Aug 29 2005; 10.1200/JCO.2005.01.370. [Abstract] [Full Text] [PDF]
	Impact of Five Prophylactic Filgrastim Schedules on Hematologic Toxicity in Early Breast Cancer Patients Treated With Epirubicin and Cyclophosphamide
	Paola Papaldo, Massimo Lopez, Paolo Marolla, Enrico Cortesi, Mauro Antimi, Edmondo Terzoli, Patrizia Vici, Carlo Barone, Gianluigi Ferretti, Serena Di Cosimo, Paolo Carlini, Cecilia Nisticò, Francesca Conti, Luigi Di Lauro, Claudio Botti, Franco Di Filippo, Alessandra Fabi, Diana Giannarelli, and Federico Calabresi
	JCO Oct 1 2005: 6908–6918. First published on Aug 29 2005; 10.1200/JCO.2005.03.099. [Abstract] [Full Text] [PDF]
	Paroxetine Is an Effective Treatment for Hot Flashes: Results From a Prospective Randomized Clinical Trial
	Vered Stearns, Rebecca Slack, Nancy Greep, Ronda Henry-Tilman, Michael Osborne, Craig Bunnell, Lynda Ullmer, Ann Gallagher, Jennifer Cullen, Edmund Gehan, Daniel F Hayes, and Claudine Isaacs
	JCO Oct 1 2005: 6919–6930. [Abstract] [Full Text] [PDF] [Publisher's Note]
	Assessment of Quality of Life in MA.17: A Randomized, Placebo-Controlled Trial of Letrozole After 5 Years of Tamoxifen in Postmenopausal Women
	Timothy J. Whelan, Paul E. Goss, James N. Ingle, Joseph L. Pater, Dongsheng Tu, Kathleen Pritchard, Shifang Liu, Lois E. Shepherd, Michael Palmer, Nicholas J. Robert, Silvana Martino, and Hyman B. Muss
	JCO Oct 1 2005: 6931–6940. First published on Sep 12 2005; 10.1200/JCO.2005.11.181. [Abstract] [Full Text] [PDF]
	Darbepoetin Alfa for the Treatment of Chemotherapy-Induced Anemia: Disease Progression and Survival Analysis From Four Randomized, Double-Blind, Placebo-Controlled Trials
	Michael Hedenus, Johan Vansteenkiste, Dusan Kotasek, Matthew Austin, and Rafael G. Amado
	JCO Oct 1 2005: 6941–6948. [Abstract] [Full Text] [PDF]
	Communicating Quality of Life Information to Cancer Patients: A Study of Six Presentation Formats
	M. Brundage, D. Feldman-Stewart, A. Leis, A. Bezjak, L. Degner, K. Velji, L. Zetes-Zanatta, D. Tu, P. Ritvo, and J. Pater
	JCO Oct 1 2005: 6949–6956. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I Pharmacokinetic Study of S-1 Plus Cisplatin in Patients With Advanced Gastric Carcinoma
	Jaffer A. Ajani, Josephine Faust, Kazumasa Ikeda, James C. Yao, Hiroshi Anbe, Kelli L. Carr, Michele Houghton, and Peter Urrea
	JCO Oct 1 2005: 6957–6965. First published on Sep 6 2005; 10.1200/JCO.2005.01.917. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Preliminary Results of a Randomized Study on Therapeutic Gain by Concurrent Chemotherapy for Regionally-Advanced Nasopharyngeal Carcinoma: NPC-9901 Trial by the Hong Kong Nasopharyngeal Cancer Study Group
	Anne W.M. Lee, W.H. Lau, Stewart Y. Tung, Daniel T.T. Chua, Rick Chappell, L. Xu, Lillian Siu, W.M. Sze, T.W. Leung, Jonathan S.T. Sham, Roger K.C. Ngan, Stephen C.K. Law, T.K. Yau, Joseph S.K. Au, Brian O'Sullivan, Ellie S.Y. Pang, S.K. O, Gordon K.H. Au, and Joseph T. Lau
	JCO Oct 1 2005: 6966–6975. [Abstract] [Full Text] [PDF]
	Phase I Study of Gefitinib Plus Celecoxib in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
	Lori J. Wirth, Robert I. Haddad, Neal I. Lindeman, Xiaojun Zhao, Jeffrey C. Lee, Victoria A. Joshi, Charles M. Norris, Jr, and Marshall R. Posner
	JCO Oct 1 2005: 6976–6981. First published on Sep 19 2005; 10.1200/JCO.2005.02.4182. [Abstract] [Full Text] [PDF]

Clinical Trials
	Comparison of Outcomes of Phase II Studies and Subsequent Randomized Control Studies Using Identical Chemotherapeutic Regimens
	Mohammad I. Zia, Lillian L. Siu, Greg R. Pond, and Eric X. Chen
	JCO Oct 1 2005: 6982–6991. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Predictors of Prostate Cancer–Specific Mortality After Radical Prostatectomy or Radiation Therapy
	Ping Zhou, Ming-Hui Chen, David McLeod, Peter R. Carroll, Judd W. Moul, and Anthony V. D’Amico
	JCO Oct 1 2005: 6992–6998. [Abstract] [Full Text] [PDF]
	Incidence of Late-Relapse Germ Cell Tumor and Outcome to Salvage Chemotherapy
	Ellen A. Ronnen, G. Varuni Kondagunta, Jennifer Bacik, Stephanie Marion, Dean F. Bajorin, Joel Sheinfeld, George J. Bosl, and Robert J. Motzer
	JCO Oct 1 2005: 6999–7004. [Abstract] [Full Text] [PDF]
	Postoperative Nomogram Predicting the 10-Year Probability of Prostate Cancer Recurrence After Radical Prostatectomy
	Andrew J. Stephenson, Peter T. Scardino, James A. Eastham, Fernando J. Bianco, Jr, Zohar A. Dotan, Christopher J. DiBlasio, Alwyn Reuther, Eric A. Klein, and Michael W. Kattan
	JCO Oct 1 2005: 7005–7012. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	High Rate of Durable Remissions After Treatment of Newly Diagnosed Aggressive Mantle-Cell Lymphoma With Rituximab Plus Hyper-CVAD Alternating With Rituximab Plus High-Dose Methotrexate and Cytarabine
	Jorge E. Romaguera, Luis Fayad, Maria A. Rodriguez, Kristine R. Broglio, Frederick B. Hagemeister, Barbara Pro, Peter McLaughlin, Anas Younes, Felipe Samaniego, Andre Goy, Andreas H. Sarris, Nam H. Dang, Michael Wang, Virginia Beasley, L. Jeffrey Medeiros, Ruth L. Katz, Harish Gagneja, Barry I. Samuels, Terry L. Smith, and Fernando F. Cabanillas
	JCO Oct 1 2005: 7013–7023. First published on Sep 6 2005; 10.1200/JCO.2005.01.1825. [Abstract] [Full Text] [PDF]
	Fludarabine in Combination With Alemtuzumab Is Effective and Feasible in Patients With Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia: Results of a Phase II Trial
	Thomas Elter, Peter Borchmann, Holger Schulz, Marcel Reiser, Sven Trelle, Roland Schnell, Markus Jensen, Peter Staib, Timo Schinköthe, Hartmut Stützer, Jürgen Rech, Martin Gramatzki, Walter Aulitzky, Ibrahim Hasan, Andreas Josting, Michael Hallek, and Andreas Engert
	JCO Oct 1 2005: 7024–7031. First published on Sep 6 2005; 10.1200/JCO.2005.01.9950. [Abstract] [Full Text] [PDF]
	Outcome of Ethnic Minorities With Acute or Chronic Leukemia Treated With Hematopoietic Stem-Cell Transplantation in the United States
	K. Scott Baker, Fausto R. Loberiza, Jr, Hongmei Yu, Mitchell S. Cairo, Brian J. Bolwell, Willem A. Bujan-Boza, Bruce M. Camitta, Juan Jose Garcia, Winston G. Ho, Jane L. Liesveld, Dipnarine Maharaj, David I. Marks, Kirk R. Schultz, Peter Wiernik, Axel R. Zander, Mary M. Horowitz, Armand Keating, and Daniel J. Weisdorf
	JCO Oct 1 2005: 7032–7042. First published on Sep 6 2005; 10.1200/JCO.2005.01.7269. [Abstract] [Full Text] [PDF]
	Lack of CpG Island Methylator Phenotype Defines a Clinical Subtype of T-Cell Acute Lymphoblastic Leukemia Associated With Good Prognosis
	Jose Roman-Gomez, Antonio Jimenez-Velasco, Xabier Agirre, Felipe Prosper, Anabel Heiniger, and Antonio Torres
	JCO Oct 1 2005: 7043–7049. [Abstract] [Full Text] [PDF]
	Treatment Results in Localized Primary Gastric Lymphoma: Data of Patients Registered Within the German Multicenter Study (GIT NHL 02/96)
	Peter Koch, Andreas Probst, Wolfgang E. Berdel, Normann A. Willich, Gabriele Reinartz, Jens Brockmann, Rüdiger Liersch, Francisco del Valle, Hermann Clasen, Carsten Hirt, Regine Breitsprecher, Rudolf Schmits, Mathias Freund, Rainer Fietkau, Peter Ketterer, Eva-Maria Freitag, Margit Hinkelbein, Achim Heinecke, Reza Parwaresch, and Markus Tiemann
	JCO Oct 1 2005: 7050–7059. First published on Aug 29 2005; 10.1200/JCO.2005.04.031. [Abstract] [Full Text] [PDF]
	Large Cleaved and Immunoblastic Lymphoma May Represent Two Distinct Clinicopathologic Entities Within the Group of Diffuse Large B-Cell Lymphomas
	Pascale De Paepe, Ruth Achten, Gregor Verhoef, Iwona Wlodarska, Michel Stul, Vera Vanhentenrijk, Marleen Praet, and Chris De Wolf-Peeters
	JCO Oct 1 2005: 7060–7068. First published on Aug 29 2005; 10.1200/JCO.2005.15.503. [Abstract] [Full Text] [PDF]
	Clinical Outcomes in t(4;14) Multiple Myeloma: A Chemotherapy-Sensitive Disease Characterized by Rapid Relapse and Alkylating Agent Resistance
	Wilfrid Jaksic, Suzanne Trudel, Hong Chang, Young Trieu, Xi Qi, Joseph Mikhael, Donna Reece, Christine Chen, and A. Keith Stewart
	JCO Oct 1 2005: 7069–7073. First published on Aug 29 2005; 10.1200/JCO.2005.17.129. [Abstract] [Full Text] [PDF]

Breast Cancer
	Impact of Patient Distance to Radiation Therapy on Mastectomy Use in Early-Stage Breast Cancer Patients
	Anneke T. Schroen, David R. Brenin, Maria D. Kelly, William A. Knaus, and Craig L. Slingluff, Jr
	JCO Oct 1 2005: 7074–7080. [Abstract] [Full Text] [PDF]
	Phase II to III Study Comparing Doxorubicin and Docetaxel With Fluorouracil, Doxorubicin, and Cyclophosphamide As First-Line Chemotherapy in Patients With Metastatic Breast Cancer: Results of a Dutch Community Setting Trial for the Clinical Trial Group of the Comprehensive Cancer Centre
	Marijke Bontenbal, Geert-Jan Creemers, Hans J. Braun, Auke C. de Boer, Jos Th. Janssen, Rieneke B. Leys, Jan B. Ruit, Swan Hoo Goey, Paul C. van der Velden, Leon G. Kerkhofs, Kristel L. Schothorst, Paul I. Schmitz, Hansje J. Bokma, Jaap Verweij, and Caroline Seynaeve
	JCO Oct 1 2005: 7081–7088. [Abstract] [Full Text] [PDF]
	Prognostic Value of Extracapsular Tumor Spread for Locoregional Control in Premenopausal Patients With Node-Positive Breast Cancer Treated With Classical Cyclophosphamide, Methotrexate, and Fluorouracil: Long-Term Observations From International Breast Cancer Study Group Trial VI
	Günther Gruber, Marco Bonetti, M. Laura Nasi, Karen N. Price, Monica Castiglione-Gertsch, Carl-Magnus Rudenstam, Stig B. Holmberg, Jurij Lindtner, Rastko Golouh, John Collins, Diana Crivellari, Antonino Carbone, Beat Thürlimann, Edda Simoncini, Martin F. Fey, Richard D. Gelber, Alan S. Coates, and Aron Goldhirsch
	JCO Oct 1 2005: 7089–7097. [Abstract] [Full Text] [PDF]
	Factors Predictive of Distant Metastases in Patients With Breast Cancer Who Have a Pathologic Complete Response After Neoadjuvant Chemotherapy
	Ana M. Gonzalez-Angulo, Sean E. McGuire, Thomas A. Buchholz, Susan L. Tucker, Henry M. Kuerer, Roman Rouzier, Shu-Wan Kau, Eugene H. Huang, Paolo Morandi, Alberto Ocana, Massimo Cristofanilli, Vicente Valero, Aman U. Buzdar, and Gabriel N. Hortobagyi
	JCO Oct 1 2005: 7098–7104. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Social Support, Psychological Distress, and Natural Killer Cell Activity in Ovarian Cancer
	Susan K. Lutgendorf, Anil K. Sood, Barrie Anderson, Stephanie McGinn, Heena Maiseri, Minh Dao, Joel I. Sorosky, Koen De Geest, Justine Ritchie, and David M. Lubaroff
	JCO Oct 1 2005: 7105–7113. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Impact of Total Lymph Node Count on Staging and Survival After Gastrectomy for Gastric Cancer: Data From a Large US-Population Database
	David D. Smith, Rebecca R. Schwarz, and Roderich E. Schwarz
	JCO Oct 1 2005: 7114–7124. [Abstract] [Full Text] [PDF]
	OncoSurge: A Strategy for Improving Resectability With Curative Intent in Metastatic Colorectal Cancer
	Graeme J. Poston, René Adam, Steven Alberts, Steven Curley, Juan Figueras, Daniel Haller, Francis Kunstlinger, Gilles Mentha, Bernard Nordlinger, Yehuda Patt, John Primrose, Mark Roh, Philippe Rougier, Theo Ruers, Hans Joachim Schmoll, Carlos Valls, Nick Jean-Nicolas Vauthey, Marleen Cornelis, and James P. Kahan
	JCO Oct 1 2005: 7125–7134. [Abstract] [Full Text] [PDF]

Sarcomas
	Phase II Study of Doxorubicin and Bevacizumab for Patients With Metastatic Soft-Tissue Sarcomas
	David R. D'Adamo, Sibyl E. Anderson, Karen Albritton, Jennifer Yamada, Elyn Riedel, Kelly Scheu, Gary K. Schwartz, Helen Chen, and Robert G. Maki
	JCO Oct 1 2005: 7135–7142. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Late Effects of Pelvic Rhabdomyosarcoma and Its Treatment in Female Survivors
	Sheri L. Spunt, Teresa A. Sweeney, Melissa M. Hudson, Catherine A. Billups, Matthew J. Krasin, and Allison L. Hester
	JCO Oct 1 2005: 7143–7151. [Abstract] [Full Text] [PDF]
	Intellectual and Functional Outcome of Children 3 Years Old or Younger Who Have CNS Malignancies
	Maryam Fouladi, Elizabeth Gilger, Mehmet Kocak, Dana Wallace, Gray Buchanan, Cara Reeves, Nicole Robbins, Thomas Merchant, Larry E. Kun, Raja Khan, Amar Gajjar, and Raymond Mulhern
	JCO Oct 1 2005: 7152–7160. [Abstract] [Full Text] [PDF]
	Long-Term Results of a Randomized Trial on Extended Use of High Dose L-Asparaginase for Standard Risk Childhood Acute Lymphoblastic Leukemia
	Andrea Pession, Maria Grazia Valsecchi, Giuseppe Masera, Willem A. Kamps, Edina Magyarosy, Carmelo Rizzari, Elisabeth R. van Wering, Luca Lo Nigro, Anna van der Does, Franco Locatelli, Giuseppe Basso, and Maurizio Aricò
	JCO Oct 1 2005: 7161–7167. [Abstract] [Full Text] [PDF]

Melanoma
	Population-Based Analysis of Prognostic Factors and Survival in Familial Melanoma
	Scott R. Florell, Kenneth M. Boucher, Gilda Garibotti, John Astle, Richard Kerber, Geraldine Mineau, Charles Wiggins, R. Dirk Noyes, Alexander Tsodikov, Lisa A. Cannon-Albright, John J. Zone, Wolfram E. Samlowski, and Sancy A. Leachman
	JCO Oct 1 2005: 7168–7177. [Abstract] [Full Text] [PDF]

Neurooncology
	Phase I Trial of Temozolomide Plus O6-Benzylguanine for Patients With Recurrent or Progressive Malignant Glioma
	Jennifer A. Quinn, Annick Desjardins, Jon Weingart, Henry Brem, M. Eileen Dolan, Shannon M. Delaney, James Vredenburgh, Jeremy Rich, Allan H. Friedman, David A. Reardon, John H. Sampson, Anthony E. Pegg, Robert C. Moschel, Robert Birch, Roger E. McLendon, James M. Provenzale, Sridharan Gururangan, Janet E. Dancey, Jill Maxwell, Sandra Tourt-Uhlig, James E. Herndon, II, Darell D. Bigner, and Henry S. Friedman
	JCO Oct 1 2005: 7178–7187. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Acupuncture-Point Stimulation for Chemotherapy-Induced Nausea and Vomiting
	Jeanette Ezzo, Andrew Vickers, Mary Ann Richardson, Claire Allen, Suzanne L. Dibble, Brian Issell, Lixing Lao, Michael Pearl, Gilbert Ramirez, Joseph A. Roscoe, Joannie Shen, Jane Shivnan, Konrad Streitberger, Imad Treish, and Grant Zhang
	JCO Oct 1 2005: 7188–7198. [Abstract] [Full Text] [PDF]

SPECIAL ARTICLES
	Design Issues of Randomized Phase II Trials and a Proposal for Phase II Screening Trials
	Lawrence V. Rubinstein, Edward L. Korn, Boris Freidlin, Sally Hunsberger, S. Percy Ivy, and Malcolm A. Smith
	JCO Oct 1 2005: 7199–7206. [Abstract] [Full Text] [PDF]
Development of Effective New Treatments for Multiple Myeloma
Kenneth C. Anderson, Richard Pazdur, and Ann T. Farrell
JCO Oct 1 2005: 7207–7211. First published on Sep 6 2005; 10.1200/JCO.2005.02.4950. [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Proliferation Marker Ki-67 in Early Breast Cancer
	Ander Urruticoechea, Ian E. Smith, and Mitch Dowsett
	JCO Oct 1 2005: 7212–7220. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Double Diagnosis in Cancer Patients and Cutaneous Reaction Related to Gemcitabine: CASE 1. Synchronous Mucosa-Associated Lymphoid Tissue Lymphoma and Gastrointestinal Stromal Tumors of the Stomach

Antonio Salar, Josep María Ramón, Carlos Barranco, Miguel Nieto, Margarita Prats, Sergi Serrano, and Carlos Besses

JCO Oct 1 2005: 7221–7223. [Full Text] [PDF]

Double Diagnosis in Cancer Patients and Cutaneous Reaction Related to Gemcitabine: CASE 2. Mixed Carcinoid-Adenocarcinoma of the Appendix

Vinay Raja, Roja Balakrishnan, Wade Bollinger, Dwayne Crabtree, Edward Downey, and Misha Mohindra

JCO Oct 1 2005: 7223–7224. [Full Text] [PDF]

Double Diagnosis in Cancer Patients and Cutaneous Reaction Related to Gemcitabine: CASE 3. Photo Therapy Recall With Gemcitabine Following Ultraviolet B Treatment

Joanna Badger, Alison Uzieblo, Sandy Srinivas, and Sewon Kang

JCO Oct 1 2005: 7224–7225. [Full Text] [PDF]

ART OF ONCOLOGY

Home to Benin

Karen A. Burch

JCO Oct 1 2005: 7226–7229. [Full Text] [PDF]

CORRESPONDENCE

Studying the Predictive/Prognostic Role of Thymidylate Synthase Genotypes in Patients With Colorectal Cancer: Is One Polymorphism Enough?

Francesco Graziano and Kazuyuki Kawakami

JCO Oct 1 2005: 7230–7231. [Full Text] [PDF]

In Reply:

Anders Jakobsen, Jens Nederby Nielsen, Niels Gyldenkerne, and Jan Lindeberg

JCO Oct 1 2005: 7231. [Full Text] [PDF]

To Treat or Not to Treat Advanced Non–Small-Cell Lung Cancer Patients With Impaired Performance Status?

Ornella Belvedere and Francesco Grossi

JCO Oct 1 2005: 7231-a–7232. [Full Text] [PDF]

In Reply:

Sofia I. Baka

JCO Oct 1 2005: 7232. [Full Text] [PDF]

What Should the Optimal Timing Be for Amifostine Administration Relative to Radiation and Chemotherapy?

Ritsuko Komaki

JCO Oct 1 2005: 7232-a–7233. [Full Text] [PDF]

In Reply:

Benjamin Movsas, Charles Scott, Corey Langer, Maria Werner-Wasik, Nicos Nicolaou, Mitchell Machtay, Colum Smith, Rita Axelrod, Linda Sarna, Todd Wasserman, and Roger Byhardt

JCO Oct 1 2005: 7233–7235. [Full Text] [PDF]

Merkel Cell Carcinoma: Improved Outcome With the Addition of Adjuvant Therapy

Michael J. Veness

JCO Oct 1 2005: 7235–7236. [Full Text] [PDF]

Merkel Cell Carcinoma: Improved Outcome With the Addition of Adjuvant Therapy

Lynn D. Wilson, Douglas Housman, and Benjamin D. Smith

JCO Oct 1 2005: 7236–7237. [Full Text] [PDF]

In Reply:

Peter J. Allen, Wilbur B. Bowne, David P. Jaques, Murray F. Brennan, Klaus J. Busam, and Daniel G. Coit

JCO Oct 1 2005: 7237–7238. [Full Text] [PDF]

Apoptosis Induction by Trastuzumab: Possible Role of the Core Biopsy Intervention

Sylvie Ménard, Serenella M. Pupa, Manuella Campiglio, Elda Taglibue, Andrea Balsari, Francesco Fagnoni, and Alberto Costa

JCO Oct 1 2005: 7238–7240. [Full Text] [PDF]

Apoptosis Induction by the Core Biopsy Procedure

Jenny C. Chang, Heidi Weiss, and Syed Mohsin

JCO Oct 1 2005: 7240. [Full Text] [PDF]

Alemtuzumab Until Minimal Residual Disease for Chronic Lymphocytic Leukemia: Is it a New Standard?

Mark Goodman

JCO Oct 1 2005: 7240-a–7241. [Full Text] [PDF]

In Reply:

Paul Moreton

JCO Oct 1 2005: 7241–7242. [Full Text] [PDF]

Potential Hazards of Necessary Collusion

Steven B. Hardin

JCO Oct 1 2005: 7242. [Full Text] [PDF]

In Reply:

Paul R. Helft

JCO Oct 1 2005: 7242-a–7243. [Full Text] [PDF]

Prophylaxis for Venous Thromboembolism in Cancer Patients With a Central Vein Catheter: New Tones for an Old Song

Giuseppe Curigliano, Marco Colleoni, Mario Mandalà, Tommaso De Pas, Gianluca Spitaleri, Filippo de Braud, and Aron Goldhirsch

JCO Oct 1 2005: 7243–7244. [Full Text] [PDF]

In Reply:

Mark N. Levine

JCO Oct 1 2005: 7244. [Full Text] [PDF]

Potential Influence of Health Systems in Accrual to Clinical Trials in Lymphoma

Karl T. Hagler and James W. Lynch, Jr

JCO Oct 1 2005: 7244-a–7245. [Full Text] [PDF]

My First American Society of Clinical Oncology Annual Meeting: Inspiration, Education, and Perspective

Lanie K. Francis

JCO Oct 1 2005: 7245–7246. [Full Text] [PDF]

Cutaneous Lymphomas Reported to the National Cancer Institute's Surveillance, Epidemiology, and End Results Program: Applying the New WHO–European Organisation for Research and Treatment of Cancer Classification System

Graça M. Dores, William F. Anderson, and Susan S. Devesa

JCO Oct 1 2005: 7246–7248. [Full Text] [PDF]

Heparin and CXCL12 Dimerization

Kadri Altundag, Ozden Altundag, and Mustafa A. Atik

JCO Oct 1 2005: 7248. [Full Text] [PDF]

Low-Molecular-Weight Heparin Versus Oral Anticoagulant Therapy for the Long-Term Treatment of Symptomatic Venous Thromboembolism: Is There Any Difference in Cancer-Related Mortality?

Gianluigi Ferretti, Emilio Bria, Diana Giannarelli, Paolo Carlini, Alessandra Felici, Mario Mandala, Paolo Papaldo, Cecilia Nistico, Alessandra Fabi, Federica Cuppone, Alain Gelibter, Edmondo Terzoli, and Francesco Cognetti

JCO Oct 1 2005: 7248-a–7250. [Full Text] [PDF]

In Reply:

Mark N. Levine, Agnes Y.Y. Lee, and Ajay K. Kakkar

JCO Oct 1 2005: 7250. [Full Text] [PDF]

ERRATUM

ERRATUM

JCO Oct 1 2005: 7251. [Full Text] [PDF]

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