EDITORIALS

Mantle Cell Lymphoma: At Last, Some Hope for Successful Innovative Treatment Strategies

Richard I. Fisher

JCO Feb 1 2005: 657–658. First published on Dec 21 2004; 10.1200/JCO.2005.10.980. [Full Text] [PDF]

Integrating Bench With Bedside: The Role of Vaccine Therapy in the Treatment of Solid Tumors

Howard L. Kaufman

JCO Feb 1 2005: 659–661. First published on Dec 21 2004; 10.1200/JCO.2005.09.908. [Full Text] [PDF]

CTLA-4 Blockade: Unveiling Immune Regulation

Glenn Dranoff

JCO Feb 1 2005: 662–664. First published on Dec 21 2004; 10.1200/JCO.2005.09.923. [Full Text] [PDF]

Perioperative Morbidity and the Rush to Chemotherapy

William P. McGuire, III

JCO Feb 1 2005: 665–666. First published on Dec 21 2004; 10.1200/JCO.2005.09.922. [Full Text] [PDF]

ORIGINAL REPORTS
Hematologic Malignancies
	Phase II Study of Proteasome Inhibitor Bortezomib in Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma
	Andre Goy, Anas Younes, Peter McLaughlin, Barbara Pro, Jorge E. Romaguera, Frederick Hagemeister, Luis Fayad, Nam H. Dang, Felipe Samaniego, Michael Wang, Kristine Broglio, Barry Samuels, Frederic Gilles, Andreas H. Sarris, Susan Hart, Elizabeth Trehu, David Schenkein, Fernando Cabanillas, and Alma M. Rodriguez
	JCO Feb 1 2005: 667–675. First published on Dec 21 2004; 10.1200/JCO.2005.03.108. [Abstract] [Full Text] [PDF]
	Phase II Clinical Experience With the Novel Proteasome Inhibitor Bortezomib in Patients With Indolent Non-Hodgkin's Lymphoma and Mantle Cell Lymphoma
	Owen A. O'Connor, John Wright, Craig Moskowitz, Jamie Muzzy, Barbara MacGregor-Cortelli, Michael Stubblefield, David Straus, Carol Portlock, Paul Hamlin, Elizabeth Choi, Otila Dumetrescu, Dixie Esseltine, Elizabeth Trehu, Julian Adams, David Schenkein, and Andrew D. Zelenetz
	JCO Feb 1 2005: 676–684. First published on Dec 21 2004; 10.1200/JCO.2005.02.050. [Abstract] [Full Text] [PDF]
	Phenotypic Heterogeneity in Multiple Myeloma Families
	Henry T. Lynch, Patrice Watson, Stefano Tarantolo, Peter H. Wiernik, Brigid Quinn-Laquer, Karin Isgur Bergsagel, Laetitia Huiart, O.I. Olopade, Hagay Sobol, Warren Sanger, David Hogg, and Dennis Weisenburger
	JCO Feb 1 2005: 685–693. [Abstract] [Full Text] [PDF]
	Rituximab in Combination With Fludarabine Chemotherapy in Low-Grade or Follicular Lymphoma
	M.S. Czuczman, A. Koryzna, A. Mohr, C. Stewart, K. Donohue, L. Blumenson, Z.P. Bernstein, P. McCarthy, A. Alam, F. Hernandez-Ilizaliturri, M. Skipper, K. Brown, A. Chanan-Khan, D. Klippenstein, P. Loud, M.K. Rock, M. Benyunes, A. Grillo-Lopez, and S.H. Bernstein
	JCO Feb 1 2005: 694–704. [Abstract] [Full Text] [PDF]
	Effect of Single-Agent Rituximab Given at the Standard Schedule or As Prolonged Treatment in Patients With Mantle Cell Lymphoma: A Study of the Swiss Group for Clinical Cancer Research (SAKK)
	Michele Ghielmini, Shu-Fang Hsu Schmitz, Sergio Cogliatti, Francesco Bertoni, Ursula Waltzer, Martin F. Fey, Daniel C. Betticher, Hubert Schefer, Gabriella Pichert, Rolf Stahel, Nicolas Ketterer, Mario Bargetzi, and Thomas Cerny
	JCO Feb 1 2005: 705–711. First published on Dec 14 2004; 10.1200/JCO.2005.04.164. [Abstract] [Full Text] [PDF]
	Efficacy and Safety of Tositumomab and Iodine-131 Tositumomab (Bexxar) in B-Cell Lymphoma, Progressive After Rituximab
	Sandra J. Horning, Anas Younes, Vinay Jain, Stewart Kroll, Jennifer Lucas, Donald Podoloff, and Michael Goris
	JCO Feb 1 2005: 712–719. First published on Dec 21 2004; 10.1200/JCO.2005.07.040. [Abstract] [Full Text] [PDF]

Immunotherapy
	Phase I Study of Sequential Vaccinations With Fowlpox-CEA(6D)-TRICOM Alone and Sequentially With Vaccinia-CEA(6D)-TRICOM, With and Without Granulocyte-Macrophage Colony-Stimulating Factor, in Patients With Carcinoembryonic Antigen–Expressing Carcinomas
	John L. Marshall, James L. Gulley, Philip M. Arlen, Patricia K. Beetham, Kwong-Yok Tsang, Rebecca Slack, James W. Hodge, Sandra Doren, Douglas W. Grosenbach, Jimmy Hwang, Evelyn Fox, Lauretta Odogwu, Susie Park, Dennis Panicali, and Jeffrey Schlom
	JCO Feb 1 2005: 720–731. First published on Dec 21 2004; 10.1200/JCO.2005.10.206. [Abstract] [Full Text] [PDF]

Molecular Oncology
	Molecular Classification of Tamoxifen-Resistant Breast Carcinomas by Gene Expression Profiling
	Maurice P.H.M. Jansen, John A. Foekens, Iris L. van Staveren, Maaike M. Dirkzwager-Kiel, Kirsten Ritstier, Maxime P. Look, Marion E. Meijer-van Gelder, Anieta M. Sieuwerts, Henk Portengen, Lambert C.J. Dorssers, Jan G.M. Klijn, and Els M.J.J. Berns
	JCO Feb 1 2005: 732–740. [Abstract] [Full Text] [PDF]
	Autoimmunity in a Phase I Trial of a Fully Human Anti-Cytotoxic T-Lymphocyte Antigen-4 Monoclonal Antibody With Multiple Melanoma Peptides and Montanide ISA 51 for Patients With Resected Stages III and IV Melanoma
	Kristin Sanderson, Ronald Scotland, Peter Lee, Dongxin Liu, Susan Groshen, Jolie Snively, Shirley Sian, Geoffrey Nichol, Thomas Davis, Tibor Keler, Michael Yellin, and Jeffrey Weber
	JCO Feb 1 2005: 741–750. First published on Dec 21 2004; 10.1200/JCO.2005.01.128. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Relationship Between Time Interval From Primary Surgery to the Start of Taxane- Plus Platinum-Based Chemotherapy and Clinical Outcome of Patients With Advanced Epithelial Ovarian Cancer: Results of a Multicenter Retrospective Italian Study
	Angiolo Gadducci, Enrico Sartori, Fabio Landoni, Paolo Zola, Tiziano Maggino, Angelo Maggioni, Stefania Cosio, Eleonora Frassi, Maria Teresa LaPresa, Luca Fuso, and Renza Cristofani
	JCO Feb 1 2005: 751–758. First published on Dec 21 2004; 10.1200/JCO.2005.03.065. [Abstract] [Full Text] [PDF]

Other Malignancies
	Mortality Risk From Squamous Cell Skin Cancer
	Gary L. Clayman, J. Jack Lee, F. Christopher Holsinger, Xian Zhou, Madeleine Duvic, Adel K. El-Naggar, Victor G. Prieto, Evelyn Altamirano, Susan L. Tucker, Sara S. Strom, Margaret L. Kripke, and Scott M. Lippman
	JCO Feb 1 2005: 759–765. [Abstract] [Full Text] [PDF]

Breast Cancer
	Discussions Regarding Reproductive Health for Young Women With Breast Cancer Undergoing Chemotherapy
	Christine M. Duffy, Susan M. Allen, and Melissa A. Clark
	JCO Feb 1 2005: 766–773. [Abstract] [Full Text] [PDF]
	Changes in Body Fat and Weight After a Breast Cancer Diagnosis: Influence of Demographic, Prognostic, and Lifestyle Factors
	Melinda L. Irwin, Anne McTiernan, Richard N. Baumgartner, Kathy B. Baumgartner, Leslie Bernstein, Frank D. Gilliland, and Rachel Ballard-Barbash
	JCO Feb 1 2005: 774–782. [Abstract] [Full Text] [PDF]
	Breast Cancer Treatment Guidelines in Older Women
	Sharon H. Giordano, Gabriel N. Hortobagyi, Shu-Wan C. Kau, Richard L. Theriault, and Melissa L. Bondy
	JCO Feb 1 2005: 783–791. [Abstract] [Full Text] [PDF]
	Randomized Phase III Trial of Capecitabine Compared With Bevacizumab Plus Capecitabine in Patients With Previously Treated Metastatic Breast Cancer
	Kathy D. Miller, Linnea I. Chap, Frankie A. Holmes, Melody A. Cobleigh, P. Kelly Marcom, Louis Fehrenbacher, Maura Dickler, Beth A. Overmoyer, James D. Reimann, Amy P. Sing, Virginia Langmuir, and Hope S. Rugo
	JCO Feb 1 2005: 792–799. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Androgen Suppression Plus Radiation Versus Radiation Alone for Patients With Stage D1/Pathologic Node-Positive Adenocarcinoma of the Prostate: Updated Results Based on National Prospective Randomized Trial Radiation Therapy Oncology Group 85-31
	Colleen A. Lawton, Kathryn Winter, David Grignon, and Miljenko V. Pilepich
	JCO Feb 1 2005: 800–807. [Abstract] [Full Text] [PDF]
	Evaluation of Tamoxifen and Anastrozole in the Prevention of Gynecomastia and Breast Pain Induced by Bicalutamide Monotherapy of Prostate Cancer
	F. Boccardo, A. Rubagotti, M. Battaglia, P. Di Tonno, F.P. Selvaggi, G. Conti, G. Comeri, A. Bertaccini, G. Martorana, P. Galassi, F. Zattoni, A. Macchiarella, A. Siragusa, G. Muscas, F. Durand, D. Potenzoni, A. Manganelli, V. Ferraris, and F. Montefiore
	JCO Feb 1 2005: 808–815. [Abstract] [Full Text] [PDF]
	Individualized Predictions of Disease Progression Following Radiation Therapy for Prostate Cancer
	Jeremy M.G. Taylor, Menggang Yu, and Howard M. Sandler
	JCO Feb 1 2005: 816–825. [Abstract] [Full Text] [PDF]
	Outcome Predictors for the Increasing PSA State After Definitive External-Beam Radiotherapy for Prostate Cancer
	Michael J. Zelefsky, Leah Ben-Porat, Howard I. Scher, Heather M. Chan, Paul A. Fearn, Zvi Y. Fuks, Steven A. Leibel, and E.S. Venkatraman
	JCO Feb 1 2005: 826–831. [Abstract] [Full Text] [PDF]
	Validation and Extension of the Memorial Sloan-Kettering Prognostic Factors Model for Survival in Patients With Previously Untreated Metastatic Renal Cell Carcinoma
	Tarek M. Mekhail, Rony M. Abou-Jawde, Gabriel BouMerhi, Sareena Malhi, Laura Wood, Paul Elson, and Ronald Bukowski
	JCO Feb 1 2005: 832–841. [Abstract] [Full Text] [PDF]

Lung Cancer
	Phase III Study of Matrix Metalloproteinase Inhibitor Prinomastat in Non–Small-Cell Lung Cancer
	Donald Bissett, Ken J. O’Byrne, J. von Pawel, Ulrich Gatzemeier, Allan Price, Marianne Nicolson, Richard Mercier, Elva Mazabel, Carol Penning, Min H. Zhang, Mary A. Collier, and Frances A. Shepherd
	JCO Feb 1 2005: 842–849. [Abstract] [Full Text] [PDF]
	Influence of Sex on Toxicity and Treatment Outcome in Small-Cell Lung Cancer
	Simron Singh, Wendy Parulekar, Nevin Murray, Ronald Feld, William K. Evans, Dongsheng Tu, and Frances A. Shepherd
	JCO Feb 1 2005: 850–856. [Abstract] [Full Text] [PDF]
	EGFR Mutations in Non–Small-Cell Lung Cancer: Analysis of a Large Series of Cases and Development of a Rapid and Sensitive Method for Diagnostic Screening With Potential Implications on Pharmacologic Treatment
	Antonio Marchetti, Carla Martella, Lara Felicioni, Fabio Barassi, Simona Salvatore, Antonio Chella, Pier P. Camplese, Teodorico Iarussi, Felice Mucilli, Andrea Mezzetti, Franco Cuccurullo, Rocco Sacco, and Fiamma Buttitta
	JCO Feb 1 2005: 857–865. [Abstract] [Full Text] [PDF]

Sarcomas
	Molecular and Clinical Analysis of Locally Advanced Dermatofibrosarcoma Protuberans Treated With Imatinib: Imatinib Target Exploration Consortium Study B2225
	Grant A. McArthur, George D. Demetri, Allan van Oosterom, Michael C. Heinrich, Maria Debiec-Rychter, Christopher L. Corless, Zariana Nikolova, Sasa Dimitrijevic, and Jonathan A. Fletcher
	JCO Feb 1 2005: 866–873. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Lymphatic Vessel Invasion As a Prognostic Factor in Patients With Primary Resected Adenocarcinomas of the Esophagogastric Junction
	Burkhard H.A. von Rahden, Hubert J. Stein, Marcus Feith, Karen Becker, and J. Rüdiger Siewert
	JCO Feb 1 2005: 874–879. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Relationship Between MYCN Copy Number and Expression in Rhabdomyosarcomas and Correlation With Adverse Prognosis in the Alveolar Subtype
	Daniel Williamson, Yong-Jie Lu, Tony Gordon, Raf Sciot, Anna Kelsey, Cyril Fisher, Christopher Poremba, John Anderson, Kathy Pritchard-Jones, and Janet Shipley
	JCO Feb 1 2005: 880–888. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I and Pharmacokinetic Study of Oral Irinotecan Given Once Daily for 5 Days Every 3 Weeks in Combination With Capecitabine in Patients With Solid Tumors
	Otto Soepenberg, Herlinde Dumez, Jaap Verweij, Dorothee Semiond, Maja J.A. deJonge, Ferry A.L.M. Eskens, Judith ter Steeg, Johan Selleslach, Sylvie Assadourian, Ger-Jan Sanderink, Alex Sparreboom, and A.T. van Oosterom
	JCO Feb 1 2005: 889–898. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Review of Exercise Intervention Studies in Cancer Patients
	Daniel A. Galvão and Robert U. Newton
	JCO Feb 1 2005: 899–909. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Small Blue Cell Tumors of the Rectum: CASE 1. Ewing’s Sarcoma of the Rectum

J. Vardy, A.M. Joshua, S.J. Clarke, P.M. Yarrow, and B.P.C. Lin

JCO Feb 1 2005: 910–912. [Full Text] [PDF]

Small Blue Cell Tumors of the Rectum: CASE 2. Small-Cell Carcinoma of the Rectum

A.M. Joshua, D. Adams, P. McKenzie, M. Solomon, and S.J. Clarke

JCO Feb 1 2005: 912–913. [Full Text] [PDF]

Small Blue Cell Tumors of the Rectum: CASE 3. Atypical Carcinoid of the Rectum

R. Sharma, D. McLeod, and S.J. Clarke

JCO Feb 1 2005: 914–915. [Full Text] [PDF]

ART OF ONCOLOGY

Multidisciplinary Care in Cancer: The Fellowship of the Ring

Frances M. Boyle, Emma Robinson, Stewart M. Dunn, and Paul C. Heinrich

JCO Feb 1 2005: 916–920. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Immunohistochemical Detection of HER1/HER2 Can Be Considered a Predictive Marker of Gefitinib Activity in Non-Small-Cell Lung Cancer?

Cristina Noberasco, Tommaso De Pas, Giuseppe Curigliano, Sara Manzoni, Lucia Dodaro, Giuseppe Pelosi, Lorenzo Spaggiari, and Filippo De Braud

JCO Feb 1 2005: 921–922. [Full Text] [PDF]

In Reply:

Masahiro Fukuoka

JCO Feb 1 2005: 922. [Full Text] [PDF]

Is Immunohistochemistry for Epidermal Growth Factor Receptor Expression a Poor Predictor of Response to Epidermal Growth Factor Receptor-Targeted Therapy?

Mamoun Younes

JCO Feb 1 2005: 923. [Full Text] [PDF]

In Reply:

Leonard Saltz

JCO Feb 1 2005: 923-a–924. [Full Text] [PDF]

Chemotherapy in Non-Small-Cell Lung Cancer: An Update of an Individual Patient Data Meta-Analysis

Sarah Burdett, Lesley Stewart, Anne Auperin, and Jean-Pierre Pignon

JCO Feb 1 2005: 924–925. [Full Text] [PDF]

In Reply:

Katsuyuki Hotta, Keitaro Matsuo, and Hiroshi Ueoka

JCO Feb 1 2005: 925–926. [Full Text] [PDF]

Treatment of Secondary Acute Myeloid Leukemia

Alessandro Pulsoni and Livio Pagano

JCO Feb 1 2005: 926–927. [Full Text] [PDF]

Observations on the Interpretation of Clinical Trials in Early Ovarian Cancer

Ann Marie C. Swart and Mahesh K.B. Parmar

JCO Feb 1 2005: 927. [Full Text] [PDF]

In Reply:

Mark F. Brady and Robert C. Young

JCO Feb 1 2005: 927-a–928. [Full Text] [PDF]

Gefitinib and Cisplatin-Based Chemotherapy in Non-Small-Cell Lung Cancer: Simply a Bad Combination?

Nicola Normanno

JCO Feb 1 2005: 928–930. [Full Text] [PDF]

In Reply:

Roy S. Herbst and Giuseppe Giaccone

JCO Feb 1 2005: 930–931. [Full Text] [PDF]

Insights Into the Role of Progesterone Receptors in Breast Cancer

Suzanne A.W. Fuqua, Yukun Cui, Adrian V. Lee, C. Kent Osborne, and Kathryn B. Horwitz

JCO Feb 1 2005: 931–932. [Full Text] [PDF]

In Reply:

Ivo A. Olivotto, Vanessa Bernstein, Pauline T. Truong, and James S. Kelly

JCO Feb 1 2005: 932–933. [Full Text] [PDF]

Update on Design of the National Surgical Adjuvant Breast and Bowel Project Trial R-04

Michael J. O'Connell, Norman Wolmark, Robert Beart, and Nicholas Petrelli

JCO Feb 1 2005: 933–934. [Full Text] [PDF]

In Reply:

Christopher H. Crane and Daniel J. Sargent

JCO Feb 1 2005: 934–935. [Full Text] [PDF]

Errata

ERRATUM

JCO Feb 1 2005: 936. [Full Text] [PDF]

ERRATUM

JCO Feb 1 2005: 936-a. [Full Text] [PDF]

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