EDITORIALS

Role of Cytochrome P450 Phenotyping in Cancer Treatment

E. Claire Dees and Paul B. Watkins

JCO Feb 20 2005: 1053–1055. First published on Jan 18 2005; 10.1200/JCO.2005.09.927. [Full Text] [PDF]

Optimizing Rituximab in B-Cell Lymphoma

Sandra J. Horning

JCO Feb 20 2005: 1056–1058. First published on Jan 18 2005; 10.1200/JCO.2005.09.924. [Full Text] [PDF]

Is There Still a Role for Induction Chemotherapy for Head and Neck Cancer?

Adam S. Garden

JCO Feb 20 2005: 1059–1060. First published on Jan 18 2005; 10.1200/JCO.2005.09.925. [Full Text] [PDF]

ORIGINAL REPORTS
Phase I and Clinical Pharmacology
	Randomized Pharmacokinetic and Pharmacodynamic Study of Docetaxel: Dosing Based on Body-Surface Area Compared With Individualized Dosing Based on Cytochrome P450 Activity Estimated Using a Urinary Metabolite of Exogenous Cortisol
	Noboru Yamamoto, Tomohide Tamura, Haruyasu Murakami, Tatsu Shimoyama, Hiroshi Nokihara, Yutaka Ueda, Ikuo Sekine, Hideo Kunitoh, Yuichiro Ohe, Tetsuro Kodama, Mikiko Shimizu, Kazuto Nishio, Naoki Ishizuka, and Nagahiro Saijo
	JCO Feb 20 2005: 1061–1069. First published on Jan 18 2005; 10.1200/JCO.2005.11.036. [Abstract] [Full Text] [PDF]
	Prospective Evaluation of the Pharmacokinetics and Toxicity Profile of Docetaxel in the Elderly
	Albert J. ten Tije, Jaap Verweij, Michael A. Carducci, Wilfried Graveland, Theresa Rogers, Tatjana Pronk, M.P. Verbruggen, Fitzroy Dawkins, and Sharyn D. Baker
	JCO Feb 20 2005: 1070–1077. [Abstract] [Full Text] [PDF]
	Phase I Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients With Advanced Cancer
	Matthew P. Goetz, David Toft, Joel Reid, Matthew Ames, Bridget Stensgard, Stephanie Safgren, Araba A. Adjei, Jeff Sloan, Pamela Atherton, Vlad Vasile, Sandra Salazaar, Alex Adjei, Gary Croghan, and Charles Erlichman
	JCO Feb 20 2005: 1078–1087. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Maximizing Therapeutic Benefit of Rituximab: Maintenance Therapy Versus Re-Treatment at Progression in Patients With Indolent Non-Hodgkin's Lymphoma—A Randomized Phase II Trial of the Minnie Pearl Cancer Research Network
	John D. Hainsworth, Sharlene Litchy, Don W. Shaffer, Van L. Lackey, Manuel Grimaldi, and F. Anthony Greco
	JCO Feb 20 2005: 1088–1095. First published on Jan 18 2005; 10.1200/JCO.2005.12.191. [Abstract] [Full Text] [PDF]
	Phase II Trial of Individualized Rituximab Dosing for Patients With CD20-Positive Lymphoproliferative Disorders
	Lucio N. Gordan, William B. Grow, Annette Pusateri, Vonda Douglas, Nancy P. Mendenhall, and James W. Lynch
	JCO Feb 20 2005: 1096–1102. First published on Jan 18 2005; 10.1200/JCO.2005.12.171. [Abstract] [Full Text] [PDF]
	Rituximab Therapy for Patients With Newly Diagnosed, Advanced-Stage, Follicular Grade I Non-Hodgkin's Lymphoma: A Phase II Trial in the North Central Cancer Treatment Group
	Thomas E. Witzig, Allen M. Vukov, Thomas M. Habermann, Susan Geyer, Paul J. Kurtin, William R. Friedenberg, William L. White, Haji I. Chalchal, Patrick J. Flynn, Thomas R. Fitch, and Debra A. Welker
	JCO Feb 20 2005: 1103–1108. First published on Jan 18 2005; 10.1200/JCO.2005.12.052. [Abstract] [Full Text] [PDF]
	Analysis of Concerted Expression of Angiogenic Growth Factors in Acute Myeloid Leukemia: Expression of Angiopoietin-2 Represents an Independent Prognostic Factor for Overall Survival
	Sonja Loges, Gerhard Heil, Melanie Bruweleit, Volker Schoder, Martin Butzal, Uta Fischer, Ursula M. Gehling, Gunter Schuch, Dieter K. Hossfeld, and Walter Fiedler
	JCO Feb 20 2005: 1109–1117. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Long-Term Survival After Cisplatin-Based Induction Chemotherapy and Radiotherapy for Nasopharyngeal Carcinoma: A Pooled Data Analysis of Two Phase III Trials
	Daniel T.T. Chua, Jun Ma, Jonathan S.T. Sham, Hai-Qiang Mai, Damon T.K. Choy, Ming-Huang Hong, Tai-Xiang Lu, and Hua-Qing Min
	JCO Feb 20 2005: 1118–1124. First published on Jan 18 2005; 10.1200/JCO.2005.12.081. [Abstract] [Full Text] [PDF]
	Hyperfractionated Accelerated Chemoradiation With Concurrent Fluorouracil-Mitomycin Is More Effective Than Dose-Escalated Hyperfractionated Accelerated Radiation Therapy Alone in Locally Advanced Head and Neck Cancer: Final Results of the Radiotherapy Cooperative Clinical Trials Group of the German Cancer Society 95-06 Prospective Randomized Trial
	Volker Budach, Martin Stuschke, Wilfried Budach, Michael Baumann, Dirk Geismar, Gerhard Grabenbauer, Ingrid Lammert, Klaus Jahnke, Georg Stueben, Thomas Herrmann, Michael Bamberg, Peter Wust, Wolfgang Hinkelbein, and Klaus-Dieter Wernecke
	JCO Feb 20 2005: 1125–1135. [Abstract] [Full Text] [PDF]

Lung Cancer
	[18F]Fluorodeoxyglucose Uptake by Positron Emission Tomography Predicts Outcome of Non–Small-Cell Lung Cancer
	Ryohei Sasaki, Ritsuko Komaki, Homer Macapinlac, Jeremy Erasmus, Pamela Allen, Kenneth Forster, Joe B. Putnam, Roy S. Herbst, Cesar A. Moran, Donald A. Podoloff, Jack A. Roth, and James D. Cox
	JCO Feb 20 2005: 1136–1143. [Abstract] [Full Text] [PDF]
	Concurrent Hyperfractionated Radiotherapy and Low-Dose Daily Carboplatin and Paclitaxel in Patients With Stage III Non–Small-Cell Lung Cancer: Long-Term Results of a Phase II Study
	Branislav Jeremic, Biljana Milicic, Ljubisa Acimovic, and Slobodan Milisavljevic
	JCO Feb 20 2005: 1144–1151. [Abstract] [Full Text] [PDF]

Breast Cancer
	Relationship of Epidermal Growth Factor Receptor Expression to ErbB-2 Signaling Activity and Prognosis in Breast Cancer Patients
	Michael P. DiGiovanna, David F. Stern, Susan M. Edgerton, Steve G. Whalen, Dan Moore, II, and Ann D. Thor
	JCO Feb 20 2005: 1152–1160. [Abstract] [Full Text] [PDF]
	Clinical Role of Multidrug Resistance Protein 1 Expression in Chemotherapy Resistance in Early-Stage Breast Cancer: The Austrian Breast and Colorectal Cancer Study Group
	Martin Filipits, Gudrun Pohl, Margaretha Rudas, Otto Dietze, Sigurd Lax, Renate Grill, Robert Pirker, Christoph C. Zielinski, Hubert Hausmaninger, Ernst Kubista, Hellmut Samonigg, and Raimund Jakesz
	JCO Feb 20 2005: 1161–1168. [Abstract] [Full Text] [PDF]
	Patterns of Resistance and Incomplete Response to Docetaxel by Gene Expression Profiling in Breast Cancer Patients
	Jenny C. Chang, Eric C. Wooten, Anna Tsimelzon, Susan G. Hilsenbeck, M. Carolina Gutierrez, Yee-Lu Tham, Mamta Kalidas, Richard Elledge, Syed Mohsin, C. Kent Osborne, Gary C. Chamness, D. Craig Allred, Michael T. Lewis, Helen Wong, and Peter O'Connell
	JCO Feb 20 2005: 1169–1177. [Abstract] [Full Text] [PDF]
	First and Subsequent Cycle Use of Pegfilgrastim Prevents Febrile Neutropenia in Patients With Breast Cancer: A Multicenter, Double-Blind, Placebo-Controlled Phase III Study
	Charles L. Vogel, Marek Z. Wojtukiewicz, Robert R. Carroll, Sergei A. Tjulandin, Luis Javier Barajas-Figueroa, Brian L. Wiens, Theresa A. Neumann, and Lee S. Schwartzberg
	JCO Feb 20 2005: 1178–1184. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Weekly Paclitaxel and Gemcitabine in Advanced Transitional-Cell Carcinoma of the Urothelium: A Phase II Hoosier Oncology Group Study
	Jinxing Li, Beth Juliar, Constantin Yiannoutsos, Rafat Ansari, Edward Fox, Michael J. Fisch, Lawrence H. Einhorn, and Christopher J. Sweeney
	JCO Feb 20 2005: 1185–1191. [Abstract] [Full Text] [PDF]
	Randomized Trial Comparing Iridium Implant Plus External-Beam Radiation Therapy With External-Beam Radiation Therapy Alone in Node-Negative Locally Advanced Cancer of the Prostate
	Jinka R. Sathya, Ian R. Davis, Jim A. Julian, Qing Guo, Dean Daya, Ian S. Dayes, Himu R. Lukka, and Mark Levine
	JCO Feb 20 2005: 1192–1199. [Abstract] [Full Text] [PDF]
	Randomized Trial of 30 Versus 20 Gy in the Adjuvant Treatment of Stage I Testicular Seminoma: A Report on Medical Research Council Trial TE18, European Organisation for the Research and Treatment of Cancer Trial 30942 (ISRCTN18525328)
	William G. Jones, Sophie D. Fossa, Graham M. Mead, J. Trevor Roberts, Michael Sokal, Alan Horwich, and Sally P. Stenning
	JCO Feb 20 2005: 1200–1208. [Abstract] [Full Text] [PDF]

Surgical Oncology
	Selective Excision of Metastatic Brain Tumors Originating in the Motor Cortex With Preservation of Function
	Robert J. Weil and Russell R. Lonser
	JCO Feb 20 2005: 1209–1217. [Abstract] [Full Text] [PDF]

Melanoma
	Molecular Staging in Stage II and III Melanoma Patients and Its Effect on Long-Term Survival
	Christiane Voit, Martina Kron, Juergen Rademaker, Markus Schwürzer-Voit, Wolfram Sterry, Lutz Weber, Cueneyt Özdemir, Thomas Proebstle, and Ulrich Keilholz
	JCO Feb 20 2005: 1218–1227. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Irinotecan Plus Oxaliplatin and Leucovorin-Modulated Fluorouracil in Advanced Pancreatic Cancer—A Groupe Tumeurs Digestives of the Fédération Nationale des Centres de Lutte Contre le Cancer Study
	Thierry Conroy, Bernard Paillot, Eric François, Roland Bugat, Jacques-Henri Jacob, Ulrich Stein, Salvador Nasca, Jean-Philippe Metges, Olivier Rixe, Pierre Michel, Emmanuelle Magherini, Aliette Hua, and Gael Deplanque
	JCO Feb 20 2005: 1228–1236. [Abstract] [Full Text] [PDF]
	Paclitaxel-Based Chemoradiotherapy in Localized Gastric Carcinoma: Degree of Pathologic Response and Not Clinical Parameters Dictated Patient Outcome
	J.A. Ajani, P.F. Mansfield, C.H. Crane, T.T. Wu, S. Lunagomez, P.M. Lynch, N. Janjan, B. Feig, J. Faust, J.C. Yao, R. Nivers, J. Morris, and P.W. Pisters
	JCO Feb 20 2005: 1237–1244. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Predictive Value of the Pretreatment Extent of Disease System in Hepatoblastoma: Results From the International Society of Pediatric Oncology Liver Tumor Study Group SIOPEL-1 Study
	Daniël C. Aronson, J. Marco Schnater, Chris R. Staalman, Gerrit J. Weverling, Jack Plaschkes, Giorgio Perilongo, Julia Brown, Angela Phillips, Jean-Bernard Otte, Piotr Czauderna, Gordon MacKinlay, and Anton Vos
	JCO Feb 20 2005: 1245–1252. [Abstract] [Full Text] [PDF]

AIDS-Related Cancer
	Profile of Patients With Kaposi's Sarcoma in the Era of Highly Active Antiretroviral Therapy
	James H. Gallafent, Susan E. Buskin, Peter B. De Turk, and David M. Aboulafia
	JCO Feb 20 2005: 1253–1260. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Does a History of Childhood Sexual Abuse Affect Sexual Outcomes in Breast Cancer Survivors?
	Gail E. Wyatt, Tamra Burns Loeb, Katherine A. Desmond, and Patricia A. Ganz
	JCO Feb 20 2005: 1261–1269. [Abstract] [Full Text] [PDF]
	Psychoeducational Intervention for Patients With Cutaneous Malignant Melanoma: A Replication Study
	Ellen H. Boesen, Lone Ross, Kirsten Frederiksen, Birthe L. Thomsen, Karin Dahlstrøm, Grethe Schmidt, Jesper Næsted, Christen Krag, and Christoffer Johansen
	JCO Feb 20 2005: 1270–1277. [Abstract] [Full Text] [PDF]
	Communicating With Realism and Hope: Incurable Cancer Patients' Views on the Disclosure of Prognosis
	Rebecca G. Hagerty, Phyllis N. Butow, Peter M. Ellis, Elizabeth A. Lobb, Susan C. Pendlebury, Natasha Leighl, Craig Mac Leod, and Martin H.N. Tattersall
	JCO Feb 20 2005: 1278–1288. [Abstract] [Full Text] [PDF]
	Should 5-Hydroxytryptamine-3 Receptor Antagonists Be Administered Beyond 24 Hours After Chemotherapy to Prevent Delayed Emesis? Systematic Re-Evaluation of Clinical Evidence and Drug Cost Implications
	Olga Geling and Hans-Georg Eichler
	JCO Feb 20 2005: 1289–1294. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Combination of Antiangiogenic Therapy With Other Anticancer Therapies: Results, Challenges, and Open Questions
	Giampietro Gasparini, Raffaele Longo, Massimo Fanelli, and Beverly A. Teicher
	JCO Feb 20 2005: 1295–1311. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Uncommon Presentations of Some Common Malignancies: CASE 1. Sequential Paraneoplastic Endocrine Syndromes in Small-Cell Lung Cancer

Stephen Mayer, Aaron M. Cypess, Olivier N. Kocher, Stuart M. Berman, Mark S. Huberman, Pamela I. Hartzband, and Balazs Halmos

JCO Feb 20 2005: 1312–1314. [Full Text] [PDF]

Uncommon Presentations of Some Common Malignancies: CASE 2. Nasopharyngeal Carcinoma Followed by Secondary Acute Promyelocytic Leukemia Presenting With Respiratory Distress

W.Y. Au, P. Lam, and T.W. Shek

JCO Feb 20 2005: 1314–1315. [Full Text] [PDF]

Uncommon Presentations of Some Common Malignancies: CASE 3. Chronic Lymphocytic Leukemia Involving the Colon and Presenting With Perforation

Mehul Lalani, John C. Rhee, Dmitriy W. Gutkin, Khalid Matin, and Jawad Ahmad

JCO Feb 20 2005: 1315–1317. [Full Text] [PDF]

ART OF ONCOLOGY

Role of Intraspinal Analgesia in Terminal Pediatric Malignancy

J.M. Saroyan, W.S. Schechter, M.E. Tresgallo, and L. Granowetter

JCO Feb 20 2005: 1318–1321. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Watchful Waiting, Temporarily Deferred Therapy, or Active Surveillance?

Chris Parker

JCO Feb 20 2005: 1322. [Full Text] [PDF]

In Reply:

Judd W. Moul

JCO Feb 20 2005: 1322-a–1323. [Full Text] [PDF]

Thalidomide With Continuous Low-Dose Dexamethasone for Multiple Myeloma

Joseph Gardyn

JCO Feb 20 2005: 1323. [Full Text] [PDF]

Prognostic Factors in Cytokine-Refractory Renal Cell Carcinoma Treated With Irinotecan, Cisplatin, and Mitomycin Chemotherapy

Jonathan Shamash, Tom Powles, Peter Wilson, Wendy Ansell, and Timothy Oliver

JCO Feb 20 2005: 1323-a–1325. [Full Text] [PDF]

Targeted Therapy for Targeted Patients: Trastuzumab in Adjuvant Treatment of Non–Small-Cell Lung Cancer

Kadri Altundag, Ozden Altundag, Paolo Morandi, and Mehmet Gunduz

JCO Feb 20 2005: 1325. [Full Text] [PDF]

Trastuzumab in the Treatment of Advanced Non–Small-Cell Lung Cancer: Is There a Role?

Gregory Kalemkerian

JCO Feb 20 2005: 1325-a–1326. [Full Text] [PDF]

In Reply:

Corey J. Langer

JCO Feb 20 2005: 1326–1327. [Full Text] [PDF]

Prognosis of Acute Monocytic Leukemia (French-American-British Classification M5)

Michael Darmon and Elie Azoulay

JCO Feb 20 2005: 1327. [Full Text] [PDF]

In Reply:

Martin S. Tallman and Jacob M. Rowe

JCO Feb 20 2005: 1327-a–1328. [Full Text] [PDF]

Potential Antiretroviral Drug Interactions With Cyclophosphamide, Doxorubicin, and Etoposide

Mark Bower, Tom Powles, Justin Stebbing, and Christina Thirlwell

JCO Feb 20 2005: 1328–1329. [Full Text] [PDF]

In Reply:

Joseph Sparano

JCO Feb 20 2005: 1329–1330. [Full Text] [PDF]

The Choice of Bilateral Prophylactic Mastectomy

F. Eisinger, L. Huiart, and H. Sobol

JCO Feb 20 2005: 1330–1331. [Full Text] [PDF]

In Reply:

Marc D. Schwartz, Beth N. Peshkin, and Claudine Isaacs

JCO Feb 20 2005: 1331–1332. [Full Text] [PDF]

Platelet-Derived Growth Factor Receptor Inhibitor Imatinib Mesylate and Docetaxel: A Modular Phase I Trial in Androgen-Independent Prostate Cancer

Matthias D. Hofer and Mark A. Rubin

JCO Feb 20 2005: 1332–1333. [Full Text] [PDF]

In Reply:

Paul Mathew, I.J. Fidler, and C. Bucana

JCO Feb 20 2005: 1333–1334. [Full Text] [PDF]

They Also Serve Who Only Stand and Wait: Do Individual Clinical Researchers, Too? Hoping for Individual Patient Data As Public Domain

Keitaro Matsuo, Katsuyuki Hotta, and Hiroshi Ueoka

JCO Feb 20 2005: 1334–1335. [Full Text] [PDF]

Toward a Clearer Understanding of the Prognostic Value of Health-Related Quality-of-Life Parameters in Breast Cancer

Fabio Efficace and Andrew Bottomley

JCO Feb 20 2005: 1335–1336. [Full Text] [PDF]

In Reply:

Pamela J. Goodwin and Marguerite Ennis

JCO Feb 20 2005: 1336. [Full Text] [PDF]

Errata

Erratum

JCO Feb 20 2005: 1337. [Full Text] [PDF]

Erratum

JCO Feb 20 2005: 1337-a–1338. [Full Text] [PDF]

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