EDITORIALS

An Embarrassment of Riches: Neoadjuvant Therapy of Rectal Cancer

Joel E. Tepper and Richard M. Goldberg

JCO Mar 1 2005: 1339–1341. First published on Jan 31 2005; 10.1200/JCO.2005.09.926. [Full Text] [PDF]

Radiofrequency Ablation of Colorectal Liver Metastases: Where Are We Really Going?

Graeme J. Poston

JCO Mar 1 2005: 1342–1344. First published on Jan 31 2005; 10.1200/JCO.2005.10.911. [Full Text] [PDF]

Obesity and Early-Stage Breast Cancer

Rowan T. Chlebowski

JCO Mar 1 2005: 1345–1347. First published on Jan 31 2005; 10.1200/JCO.2005.10.949. [Full Text] [PDF]

Dietary Counseling Is Beneficial for the Patient With Cancer

Cheryl L. Rock

JCO Mar 1 2005: 1348–1349. First published on Jan 31 2005; 10.1200/JCO.2005.10.950. [Full Text] [PDF]

ORIGINAL REPORTS
Gastrointestinal Cancer
	Phase I Trial of Capecitabine and Weekly Irinotecan in Combination With Radiotherapy for Neoadjuvant Therapy of Rectal Cancer
	Ralf-Dieter Hofheinz, Bolko von Gerstenberg-Helldorf, Frederik Wenz, Ulrike Gnad, Uta Kraus-Tiefenbacher, Albrecht Müldner, Rüdiger Hehlmann, Stefan Post, Andreas Hochhaus, and Frank Willeke
	JCO Mar 1 2005: 1350–1357. First published on Jan 31 2005; 10.1200/JCO.2005.04.171. [Abstract] [Full Text] [PDF]
	Predictors of Survival After Radiofrequency Thermal Ablation of Colorectal Cancer Metastases to the Liver: A Prospective Study
	Eren Berber, Robert Pelley, and Allan E. Siperstein
	JCO Mar 1 2005: 1358–1364. First published on Jan 31 2005; 10.1200/JCO.2005.12.039. [Abstract] [Full Text] [PDF]
	Thymidylate Synthase and Methylenetetrahydrofolate Reductase Gene Polymorphism in Normal Tissue As Predictors of Fluorouracil Sensitivity
	Anders Jakobsen, Jens Nederby Nielsen, Niels Gyldenkerne, and Jan Lindeberg
	JCO Mar 1 2005: 1365–1369. [Abstract] [Full Text] [PDF]

Breast Cancer
	Weight, Weight Gain, and Survival After Breast Cancer Diagnosis
	Candyce H. Kroenke, Wendy Y. Chen, Bernard Rosner, and Michelle D. Holmes
	JCO Mar 1 2005: 1370–1378. First published on Jan 31 2005; 10.1200/JCO.2005.01.079. [Abstract] [Full Text] [PDF]
	Size of Breast Cancer Metastases in Axillary Lymph Nodes: Clinical Relevance of Minimal Lymph Node Involvement
	Marco Colleoni, Nicole Rotmensz, Giulia Peruzzotti, Patrick Maisonneuve, Giovanni Mazzarol, Giancarlo Pruneri, Alberto Luini, Mattia Intra, Paolo Veronesi, Viviana Galimberti, Rosalba Torrisi, Anna Cardillo, Aron Goldhirsch, and Giuseppe Viale
	JCO Mar 1 2005: 1379–1389. [Abstract] [Full Text] [PDF]
	Site of Primary Tumor Has a Prognostic Role in Operable Breast Cancer: The International Breast Cancer Study Group Experience
	Marco Colleoni, David Zahrieh, Richard D. Gelber, Stig B. Holmberg, Jan E. Mattsson, Carl-Magnus Rudenstam, Jurij Lindtner, Darja Erzen, Raymond Snyder, John Collins, Martin F. Fey, Beat Thürlimann, Diana Crivellari, Elizabeth Murray, Caesar Mendiola, Olivia Pagani, Monica Castiglione-Gertsch, Alan S. Coates, Karen Price, and Aron Goldhirsch
	JCO Mar 1 2005: 1390–1400. [Abstract] [Full Text] [PDF]
	Gemcitabine, Epirubicin, and Paclitaxel Versus Fluorouracil, Epirubicin, and Cyclophosphamide As First-Line Chemotherapy in Metastatic Breast Cancer: A Central European Cooperative Oncology Group International, Multicenter, Prospective, Randomized Phase III Trial
	Christoph Zielinski, Semir Beslija, Zrinka Mrsic-Krmpotic, Marzena Welnicka-Jaskiewicz, Christoph Wiltschke, Zsuzsanna Kahan, Mislav Grgic, Valentina Tzekova, Moshe Inbar, Jozika Cervek, Ivan Chernozemsky, Janos Szanto, Stanislav Spanik, Maria Wagnerova, Nicolae Ghilezan, Janusz Pawlega, Damir Vrbanec, Dmitry Khamtsov, Victoria Soldatenkova, and Thomas Brodowicz
	JCO Mar 1 2005: 1401–1408. [Abstract] [Full Text] [PDF]
	Postmastectomy Radiation and Mortality in Women With T1-2 Node-Positive Breast Cancer
	Benjamin D. Smith, Grace L. Smith, and Bruce G. Haffty
	JCO Mar 1 2005: 1409–1419. [Abstract] [Full Text] [PDF]
	Circulating Tumor Cells: A Novel Prognostic Factor for Newly Diagnosed Metastatic Breast Cancer
	Massimo Cristofanilli, Daniel F. Hayes, G. Thomas Budd, Mathew J. Ellis, Alison Stopeck, James M. Reuben, Gerald V. Doyle, Jeri Matera, W. Jeffrey Allard, M. Craig Miller, Herbert A. Fritsche, Gabriel N. Hortobagyi, and Leon W.M.M. Terstappen
	JCO Mar 1 2005: 1420–1430. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Dietary Counseling Improves Patient Outcomes: A Prospective, Randomized, Controlled Trial in Colorectal Cancer Patients Undergoing Radiotherapy
	Paula Ravasco, Isabel Monteiro-Grillo, Pedro Marques Vidal, and Maria Ermelinda Camilo
	JCO Mar 1 2005: 1431–1438. First published on Jan 31 2005; 10.1200/JCO.2005.02.054. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Multi-Institutional Randomized Phase II Trial of the Epothilone B Analog Ixabepilone (BMS-247550) With or Without Estramustine Phosphate in Patients With Progressive Castrate Metastatic Prostate Cancer
	Matthew D. Galsky, Eric J. Small, William K. Oh, Isan Chen, David C. Smith, A. Dimitrios Colevas, Lou Martone, Tracy Curley, Anthony DeLaCruz, Howard I. Scher, and W. Kevin Kelly
	JCO Mar 1 2005: 1439–1446. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Supradose Intra-Arterial Cisplatin and Concurrent Radiation Therapy for the Treatment of Stage IV Head and Neck Squamous Cell Carcinoma Is Feasible and Efficacious in a Multi-Institutional Setting: Results of Radiation Therapy Oncology Group Trial 9615
	K. Thomas Robbins, Parvesh Kumar, Jonathan Harris, Timothy McCulloch, Anthony Cmelak, Robert Sofferman, Paul Levine, Robert Weisman, William Wilson, Ernest Weymuller, and Karen Fu
	JCO Mar 1 2005: 1447–1454. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Preoperative Serum Squamous Cell Carcinoma Antigen Levels in Clinical Decision Making for Patients With Early-Stage Cervical Cancer
	Nathalie Reesink-Peters, Jacobus van der Velden, Klaske A. ten Hoor, H. Marike Boezen, Elisabeth G.E. de Vries, Marten S. Schilthuis, Marian J.E. Mourits, Hans W. Nijman, Jan G. Aalders, Harry Hollema, Elisabeth Pras, Jitze M. Duk, and Ate G.J. van der Zee
	JCO Mar 1 2005: 1455–1462. [Abstract] [Full Text] [PDF]
	Plasma Bikunin As a Favorable Prognostic Factor in Ovarian Cancer
	Hidenori Matsuzaki, Hiroshi Kobayashi, Tatsuo Yagyu, Kiyoshi Wakahara, Toshiharu Kondo, Noriyuki Kurita, Hideo Sekino, Kiyokazu Inagaki, Mika Suzuki, Naohiro Kanayama, and Toshihiko Terao
	JCO Mar 1 2005: 1463–1472. [Abstract] [Full Text] [PDF]

Melanoma
	Prognostic Significance of Activated Akt Expression in Melanoma: A Clinicopathologic Study of 292 Cases
	Derek L. Dai, Magdalena Martinka, and Gang Li
	JCO Mar 1 2005: 1473–1482. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	TP53 Mutations and Outcome in Osteosarcoma: A Prospective, Multicenter Study
	Jay S. Wunder, Nalan Gokgoz, Robert Parkes, Shelley B. Bull, Sasha Eskandarian, Aileen M. Davis, Chris P. Beauchamp, Ernest U. Conrad, Robert J. Grimer, John H. Healey, David Malkin, D.C. Mangham, Michael J. Rock, Robert S. Bell, and Irene L. Andrulis
	JCO Mar 1 2005: 1483–1490. [Abstract] [Full Text] [PDF]
	Atypical Teratoid/Rhabdoid Tumors (ATRT): Improved Survival in Children 3 Years of Age and Older With Radiation Therapy and High-Dose Alkylator-Based Chemotherapy
	Tanya M. Tekautz, Christine E. Fuller, Susan Blaney, Maryam Fouladi, Alberto Broniscer, Thomas E. Merchant, Matthew Krasin, James Dalton, Gregory Hale, Larry E. Kun, Dana Wallace, Richard J. Gilbertson, and Amar Gajjar
	JCO Mar 1 2005: 1491–1499. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Rituximab Plus Short-Duration Chemotherapy As First-Line Treatment for Follicular Non-Hodgkin’s Lymphoma: A Phase II Trial of the Minnie Pearl Cancer Research Network
	John D. Hainsworth, Sharlene Litchy, Lisa H. Morrissey, Michael B. Andrews, Manuel Grimaldi, Matthew McCarty, and F. Anthony Greco
	JCO Mar 1 2005: 1500–1506. First published on Jan 4 2005; 10.1200/JCO.2005.05.004. [Abstract] [Full Text] [PDF]
	Results of Whole-Brain Radiation As Salvage of Methotrexate Failure for Immunocompetent Patients With Primary CNS Lymphoma
	Paul L. Nguyen, Arnab Chakravarti, Dianne M. Finkelstein, Fred H. Hochberg, Tracy T. Batchelor, and Jay S. Loeffler
	JCO Mar 1 2005: 1507–1513. [Abstract] [Full Text] [PDF]
	Common Polymorphism G(-248)A in the Promoter Region of the bax Gene Results in Significantly Shorter Survival in Patients With Chronic Lymphocytic Leukemia Once Treatment Is Initiated
	Jane Starczynski, Chris Pepper, Guy Pratt, Laura Hooper, Alun Thomas, Donald Milligan, Paul Bentley, and Christopher Fegan
	JCO Mar 1 2005: 1514–1521. [Abstract] [Full Text] [PDF]
	Salvage Radiotherapy in Patients With Relapsed and Refractory Hodgkin’s Lymphoma: A Retrospective Analysis From the German Hodgkin Lymphoma Study Group
	Andreas Josting, Lucia Nogová, Jeremy Franklin, Jan-Peter Glossmann, Hans Theodor Eich, Markus Sieber, Thomas Schober, Heinz-Dietrich Boettcher, Ulrich Schulz, Rolf-Peter Müller, Volker Diehl, and Andreas Engert
	JCO Mar 1 2005: 1522–1529. First published on Jan 4 2005; 10.1200/JCO.2005.05.022. [Abstract] [Full Text] [PDF]

Lung Cancer
	High Risk of Brain Metastases in Surgically Staged IIIA Non–Small-Cell Lung Cancer Patients Treated With Surgery, Chemotherapy, and Radiation
	Harvey J. Mamon, Beow Yong Yeap, Pasi A. Jänne, Jason Reblando, Sarah Shrager, Michael T. Jaklitsch, Steven Mentzer, Jeanne M. Lukanich, David J. Sugarbaker, Elizabeth H. Baldini, Stuart Berman, Arthur Skarin, and Raphael Bueno
	JCO Mar 1 2005: 1530–1537. [Abstract] [Full Text] [PDF]
	Pivotal Study of Iodine-131–Labeled Chimeric Tumor Necrosis Treatment Radioimmunotherapy in Patients With Advanced Lung Cancer
	Shaoliang Chen, Like Yu, Changying Jiang, Yan Zhao, Da Sun, Shenyu Li, Guoqing Liao, Yangchun Chen, Qing Fu, Qun Tao, Dan Ye, Peisheng Hu, Leslie A. Khawli, Clive R. Taylor, Alan L. Epstein, and Dian Wen Ju
	JCO Mar 1 2005: 1538–1547. [Abstract] [Full Text] [PDF]

Prevention
	Health Care Provider-Directed Intervention to Increase Colorectal Cancer Screening Among Veterans: Results of a Randomized Controlled Trial
	M. Rosario Ferreira, Nancy C. Dolan, Marian L. Fitzgibbon, Terry C. Davis, Nicolle Gorby, Lisa Ladewski, Dachao Liu, Alfred W. Rademaker, Franklin Medio, Brian P. Schmitt, and Charles L. Bennett
	JCO Mar 1 2005: 1548–1554. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Intrathecal Mafosfamide: A Preclinical Pharmacology and Phase I Trial
	Susan M. Blaney, Frank M. Balis, Stacey Berg, Carola A.S. Arndt, Richard Heideman, J. Russell Geyer, Roger Packer, Peter C. Adamson, Kurt Jaeckle, Renee Klenke, Alberta Aikin, Robert Murphy, Cynthia McCully, and David G. Poplack
	JCO Mar 1 2005: 1555–1563. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Diagnosis and Management of Waldenstrom's Macroglobulinemia
	Meletios A. Dimopoulos, Robert A. Kyle, Athanasios Anagnostopoulos, and Steven P. Treon
	JCO Mar 1 2005: 1564–1577. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Dramatic Responses to Therapy in Rare Tumors: CASE 1. Complete Remission to Corticosteroids in an Octreotide-Refractory Thymoma

M. Tiseo, F. Monetti, M. Ferrarini, J. Serrano, M. Chiaramondia, and A. Ardizzoni

JCO Mar 1 2005: 1578–1579. [Full Text] [PDF]

Dramatic Responses to Therapy in Rare Tumors: CASE 2. Response in a Patient With Metastatic Adrenal Cortical Carcinoma With Thalidomide

Reinaldo Chacón, Gabriela Tossen, Fernando Sanchez Loria, and Matías Chacón

JCO Mar 1 2005: 1579–1580. [Full Text] [PDF]

Dramatic Responses to Therapy in Rare Tumors: CASE 3. Pathologic Complete Remission of Metastatic Gastrointestinal Stromal Tumor After Imatinib Mesylate

Matías Chacón, Enrique Roca, Eduardo Huertas, Fernando Sanchez Loria, and Enzo Domenechini

JCO Mar 1 2005: 1580–1582. [Full Text] [PDF]

ART OF ONCOLOGY

Genuine Encounters: Responses to Death

Robin K. Matsuyama

JCO Mar 1 2005: 1583–1584. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Long-Term Survival and Cure of Patients Diagnosed With Breast Cancer Before Age 50 Years

Hermann Brenner and Timo Hakulinen

JCO Mar 1 2005: 1585. [Full Text] [PDF]

In Reply:

Stephanie Green

JCO Mar 1 2005: 1586. [Full Text] [PDF]

Acetaminophen in Cancer Pain

Janet Hardy, Elizabeth Reymond, and Margaret Charles

JCO Mar 1 2005: 1586-a. [Full Text] [PDF]

In Reply:

Martin Stockler

JCO Mar 1 2005: 1586-b–1587. [Full Text] [PDF]

Regarding "Abbreviated Course of Radiation Therapy in Older Patients with Glioblastoma Multiforme: A Prospective Randomized Clinical Trial"

Marc C. Chamberlain, Lawrence D. Recht, and Michael Glantz

JCO Mar 1 2005: 1587–1588. [Full Text] [PDF]

In Reply:

Wilson Roa, Raul Urtasun, Glenn Bauman, J. Gregory Cairncross, and Peter Forsyth

JCO Mar 1 2005: 1588. [Full Text] [PDF]

Antibacterial Essential Oils Reduce Tumor Smell and Inflammation in Cancer Patients

Patrick H. Warnke, Eugene Sherry, Paul A.J. Russo, Martin Sprengel, Yahya Açil, Joachim P. Bredee, Sabine Schubert, Jorg Wiltfang, and Ingo N. Springer

JCO Mar 1 2005: 1588-a–1589. [Full Text] [PDF]

The Metrics of Clinical Trials

James Wright, Lee Fairclough, Janet Manzo, Lynda Phippard, Bobbi Smuck, and Joanne Lacourciere

JCO Mar 1 2005: 1589–1590. [Full Text] [PDF]

In Reply:

Thomas E. Goffman and Eli Glatstein

JCO Mar 1 2005: 1590–1591. [Full Text] [PDF]

FDG-PET in Addition to Conventional Work-Up in Non–Small-Cell Lung Cancer

Harm van Tinteren, Egbert F. Smit, and Otto S. Hoekstra

JCO Mar 1 2005: 1591. [Full Text] [PDF]

In Reply:

M.J. Fulham, B.C. McCaughan, M.J. Boyer, J.M. McLean, P.M. Kenny, M.T. King, C.A. Pollicino, and R.C. Viney

JCO Mar 1 2005: 1591-a–1592. [Full Text] [PDF]

No Therapeutic Effect of Extended Lymph Node Dissection for Gastric Cancer

Wei-Jei Lee

JCO Mar 1 2005: 1592–1593. [Full Text] [PDF]

In Reply:

H.H. Hartgrink and C.J.H. van de Velde

JCO Mar 1 2005: 1593. [Full Text] [PDF]

Erratum

ERRATUM

JCO Mar 1 2005: 1594. [Full Text] [PDF]

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