EDITORIALS

Treatment Options in Metastatic Renal Carcinoma: An Embarrassment of Riches

Nicholas J. Vogelzang

JCO Jan 1 2006: 1–3. First published on Dec 5 2005; 10.1200/JCO.2005.03.7234. [Full Text] [PDF]

New Targets, Therapies, and Toxicities: Lessons to Be Learned

Walter M. Stadler

JCO Jan 1 2006: 4–5. First published on Nov 28 2005; 10.1200/JCO.2005.04.2408. [Full Text] [PDF]

Major Progress for a Less Common Cancer

Gini F. Fleming

JCO Jan 1 2006: 6–8. First published on Dec 5 2005; 10.1200/JCO.2005.03.8836. [Full Text] [PDF]

Hormone Replacement Therapy and Decreased Lung Cancer Survival

Jill M. Siegfried

JCO Jan 1 2006: 9–10. First published on Nov 28 2005; 10.1200/JCO.2005.04.2531. [Full Text] [PDF]

Desmoid Tumors Respond to Chemotherapy: Defying the Dogma in Oncology

Shreyaskumar R. Patel and Robert S. Benjamin

JCO Jan 1 2006: 11–12. First published on Dec 5 2005; 10.1200/JCO.2005.03.6566. [Full Text] [PDF]

Efaproxiral: Should We Hold Our Breath?

Penny K. Sneed

JCO Jan 1 2006: 13–15. First published on Nov 28 2005; 10.1200/JCO.2005.03.8281. [Full Text] [PDF]

ORIGINAL REPORTS
Genitourinary Cancer
	Activity of SU11248, a Multitargeted Inhibitor of Vascular Endothelial Growth Factor Receptor and Platelet-Derived Growth Factor Receptor, in Patients With Metastatic Renal Cell Carcinoma
	Robert J. Motzer, M. Dror Michaelson, Bruce G. Redman, Gary R. Hudes, George Wilding, Robert A. Figlin, Michelle S. Ginsberg, Sindy T. Kim, Charles M. Baum, Samuel E. DePrimo, Jim Z. Li, Carlo L. Bello, Charles P. Theuer, Daniel J. George, and Brian I. Rini
	JCO Jan 1 2006: 16–24. First published on Dec 5 2005; 10.1200/JCO.2005.02.2574. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Safety, Pharmacokinetic, and Antitumor Activity of SU11248, a Novel Oral Multitarget Tyrosine Kinase Inhibitor, in Patients With Cancer
	Sandrine Faivre, Catherine Delbaldo, Karina Vera, Caroline Robert, Stéphanie Lozahic, Nathalie Lassau, Carlo Bello, Samuel Deprimo, Nicoletta Brega, Giorgio Massimini, Jean-Pierre Armand, Paul Scigalla, and Eric Raymond
	JCO Jan 1 2006: 25–35. First published on Nov 28 2005; 10.1200/JCO.2005.02.2194. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Randomized Phase III Trial of Whole-Abdominal Irradiation Versus Doxorubicin and Cisplatin Chemotherapy in Advanced Endometrial Carcinoma: A Gynecologic Oncology Group Study
	Marcus E. Randall, Virginia L. Filiaci, Hyman Muss, Nick M. Spirtos, Robert S. Mannel, Jeffrey Fowler, J. Tate Thigpen, and Jo Ann Benda
	JCO Jan 1 2006: 36–44. First published on Dec 5 2005; 10.1200/JCO.2004.00.7617. [Abstract] [Full Text] [PDF]
	Comparison of CA-125 and Standard Definitions of Progression of Ovarian Cancer in the Intergroup Trial of Cisplatin and Paclitaxel Versus Cisplatin and Cyclophosphamide
	Gordon J.S. Rustin, Petra Timmers, Ann Nelstrop, Gavin Shreeves, Soeren M. Bentzen, Benoit Baron, Martine J. Piccart, Kamma Bertelsen, Gavin Stuart, James Cassidy, and Elizabeth Eisenhauer
	JCO Jan 1 2006: 45–51. [Abstract] [Full Text] [PDF]
	Early Identification of Resistance to First-Line Single-Agent Methotrexate in Patients With Persistent Trophoblastic Disease
	Nienke E. van Trommel, Leon F. Massuger, Charles P. Schijf, Marianne J. ten Kate-Booij, Fred C. Sweep, and Chris M. Thomas
	JCO Jan 1 2006: 52–58. [Abstract] [Full Text] [PDF]

Lung Cancer
	Hormone Replacement Therapy Is Associated With Decreased Survival in Women With Lung Cancer
	Apar Kishor Ganti, Abe E. Sahmoun, Amit W. Panwalkar, Ketki K. Tendulkar, and Anil Potti
	JCO Jan 1 2006: 59–63. First published on Nov 28 2005; 10.1200/JCO.2005.02.9827. [Abstract] [Full Text] [PDF]
	First-Line Single Agent Treatment With Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer: A Phase II Study
	Seiji Niho, Kaoru Kubota, Koichi Goto, Kiyotaka Yoh, Hironobu Ohmatsu, Ryutaro Kakinuma, Nagahiro Saijo, and Yutaka Nishiwaki
	JCO Jan 1 2006: 64–69. [Abstract] [Full Text] [PDF]
	Neuroendocrine Neoplasms of the Lung: A Prognostic Spectrum
	Hisao Asamura, Toru Kameya, Yoshihiro Matsuno, Masayuki Noguchi, Hirohito Tada, Yuichi Ishikawa, Tomoyuki Yokose, Shi-Xu Jiang, Takeshi Inoue, Ken Nakagawa, Kinuko Tajima, and Kanji Nagai
	JCO Jan 1 2006: 70–76. [Abstract] [Full Text] [PDF]

Breast Cancer
	Patterns of Care in Early-Stage Breast Cancer Survivors in the First Year After Cessation of Active Treatment
	Jeanne S. Mandelblatt, William F. Lawrence, Jennifer Cullen, Annette L. Stanton, Janice L. Krupnick, Lorna Kwan, and Patricia A. Ganz
	JCO Jan 1 2006: 77–84. [Abstract] [Full Text] [PDF]
	Factors Related to Underuse of Surveillance Mammography Among Breast Cancer Survivors
	Nancy L. Keating, Mary Beth Landrum, Edward Guadagnoli, Eric P. Winer, and John Z. Ayanian
	JCO Jan 1 2006: 85–94. [Abstract] [Full Text] [PDF]
	Psychological Distress in Men With Breast Cancer
	Kate Brain, Buddug Williams, Rachel Iredale, Liz France, and Jonathon Gray
	JCO Jan 1 2006: 95–101. [Abstract] [Full Text] [PDF]

Sarcomas
	Successful Chemotherapeutic Modality of Doxorubicin Plus Dacarbazine for the Treatment of Desmoid Tumors in Association With Familial Adenomatous Polyposis
	Makoto Gega, Hidenori Yanagi, Reigetsu Yoshikawa, Masafumi Noda, Hiroki Ikeuchi, Kiyoshi Tsukamoto, Tsutomu Oshima, Yoshinori Fujiwara, Nobuhisa Gondo, Kazuo Tamura, Joji Utsunomiya, Tomoko Hashimoto-Tamaoki, and Takehira Yamamura
	JCO Jan 1 2006: 102–105. [Abstract] [Full Text] [PDF]

Neurooncology
	Phase III Study of Efaproxiral As an Adjunct to Whole-Brain Radiation Therapy for Brain Metastases
	John H. Suh, Baldassarre Stea, Abdenour Nabid, John J. Kresl, André Fortin, Jean-Philippe Mercier, Neil Senzer, Eric L. Chang, Adam P. Boyd, Pablo J. Cagnoni, and Edward Shaw
	JCO Jan 1 2006: 106–114. First published on Nov 28 2005; 10.1200/JCO.2004.00.1768. [Abstract] [Full Text] [PDF]
	Salvage Radioimmunotherapy With Murine Iodine-131–Labeled Antitenascin Monoclonal Antibody 81C6 for Patients With Recurrent Primary and Metastatic Malignant Brain Tumors: Phase II Study Results
	David A. Reardon, Gamal Akabani, R. Edward Coleman, Allan H. Friedman, Henry S. Friedman, James E. Herndon, II, Roger E. McLendon, Charles N. Pegram, James M. Provenzale, Jennifer A. Quinn, Jeremy N. Rich, James J. Vredenburgh, Annick Desjardins, Sri Guruangan, Michael Badruddoja, Jeanette M. Dowell, Terence Z. Wong, Xiao-Guang Zhao, Michael R. Zalutsky, and Darell D. Bigner
	JCO Jan 1 2006: 115–122. [Abstract] [Full Text] [PDF]

Diagnostics
	Low Value of [18F]-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography in Primary Staging of Early-Stage Cervical Cancer Before Radical Hysterectomy
	Hung-Hsueh Chou, Ting-Chang Chang, Tzu-Chen Yen, Koon-Kwan Ng, Swei Hsueh, Shih-Ya Ma, Chee-Jen Chang, Huei-Jean Huang, Angel Chao, Tzu-I Wu, Shih-Ming Jung, Yen-Ching Wu, Cheng-Tao Lin, Kuan-Gen Huang, and Chyong-Huey Lai
	JCO Jan 1 2006: 123–128. [Abstract] [Full Text] [PDF]

Prevention
	Preliminary Results on Safety and Activity of a Randomized, Double-Blind, 2 x 2 Trial of Low-Dose Tamoxifen and Fenretinide for Breast Cancer Prevention in Premenopausal Women
	Aliana Guerrieri-Gonzaga, Chris Robertson, Bernardo Bonanni, Davide Serrano, Massimiliano Cazzaniga, Serena Mora, Marcella Gulisano, Harriet Johansson, Franca Formelli, Mattia Intra, Antuono Latronico, Dorella Franchi, Giuseppe Pelosi, Karen Johnson, and Andrea Decensi
	JCO Jan 1 2006: 129–135. [Abstract] [Full Text] [PDF] [Publisher's Note]

Clinical Trials
	Unconventional Anticancer Agents: A Systematic Review of Clinical Trials
	Andrew J. Vickers, Joyce Kuo, and Barrie R. Cassileth
	JCO Jan 1 2006: 136–140. [Abstract] [Full Text] [PDF]
	Impact of the Year 2000 Medicare Policy Change on Older Patient Enrollment to Cancer Clinical Trials
	Joseph M. Unger, Charles A. Coltman, Jr, John J. Crowley, Laura F. Hutchins, Silvana Martino, Robert B. Livingston, John S. Macdonald, Charles D. Blanke, David R. Gandara, E. David Crawford, and Kathy S. Albain
	JCO Jan 1 2006: 141–144. First published on Dec 5 2005; 10.1200/JCO.2005.02.8928. [Abstract] [Full Text] [PDF]

Bone Marrow Transplantation
	Comparable Long-Term Survival After Unrelated and HLA-Matched Sibling Donor Hematopoietic Stem Cell Transplantations for Acute Leukemia in Children Younger Than 18 Months
	Mary Eapen, Pablo Rubinstein, Mei-Jie Zhang, Bruce M. Camitta, Cladd Stevens, Mitchell S. Cairo, Stella M. Davies, John J. Doyle, Joanne Kurtzberg, Michael A. Pulsipher, Juan J. Ortega, Andromachi Scaradavou, Mary M. Horowitz, and John E. Wagner
	JCO Jan 1 2006: 145–151. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Intensive Therapy With Growth Factor Support for Patients With Ewing Tumor Metastatic at Diagnosis: Pediatric Oncology Group/Children's Cancer Group Phase II Study 9457—A Report From the Children's Oncology Group
	Mark L. Bernstein, Meenakshi Devidas, Dominique Lafreniere, Abdul-Kader Souid, Paul A. Meyers, Mark Gebhardt, Kimo Stine, Richard Nicholas, Elizabeth J. Perlman, Ronald Dubowy, Irving W. Wainer, Paul S. Dickman, Michael P. Link, Allen Goorin, and Holcombe E. Grier
	JCO Jan 1 2006: 152–159. [Abstract] [Full Text] [PDF]
	Decision Making in Pediatric Oncology: Who Should Take the Lead? The Decisional Priority in Pediatric Oncology Model
	Simon N. Whitney, Angela M. Ethier, Ernest Frugé, Stacey Berg, Laurence B. McCullough, and Marilyn Hockenberry
	JCO Jan 1 2006: 160–165. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Clinical Experience With Intravenous and Oral Formulations of the Novel Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid in Patients With Advanced Hematologic Malignancies
	Owen A. O'Connor, Mark L. Heaney, Lawrence Schwartz, Stacie Richardson, Robert Willim, Barbara MacGregor-Cortelli, Tracey Curly, Craig Moskowitz, Carol Portlock, Steven Horwitz, Andrew D. Zelenetz, Stanley Frankel, Victoria Richon, Paul Marks, and William K. Kelly
	JCO Jan 1 2006: 166–173. First published on Dec 5 2005; 10.1200/JCO.2005.01.9679. [Abstract] [Full Text] [PDF]
	Phase II Study of Oral Fludarabine Phosphate in Relapsed Indolent B-Cell Non-Hodgkin's Lymphoma
	Kensei Tobinai, Takashi Watanabe, Michinori Ogura, Yasuo Morishima, Yoshiaki Ogawa, Ken-ichi Ishizawa, Hironobu Minami, Atae Utsunomiya, Masafumi Taniwaki, Takashi Terauchi, Shigeru Nawano, Masaki Matsusako, Yoshihiro Matsuno, Shigeo Nakamura, Shigeo Mori, Yasuo Ohashi, Masaki Hayashi, Taku Seriu, and Tomomitsu Hotta
	JCO Jan 1 2006: 174–180. First published on Dec 5 2005; 10.1200/JCO.2005.03.9313. [Abstract] [Full Text] [PDF]
	Radiotherapy As Primary Treatment for Stage IE and IIE Nasal Natural Killer/T-Cell Lymphoma
	Ye-Xiong Li, Bo Yao, Jing Jin, Wei-Hu Wang, Yue-Ping Liu, Yong-Wen Song, Shu-Lian Wang, Xin-Fan Liu, Li-Qiang Zhou, Xiao-Hui He, Ning Lu, and Zi-Hao Yu
	JCO Jan 1 2006: 181–189. [Abstract] [Full Text] [PDF] [Publisher's Note]

ASCO SPECIAL ARTICLE
	Clinical Cancer Advances 2005: Major Research Advances in Cancer Treatment, Prevention, and Screening—A Report From the American Society of Clinical Oncology
	Roy S. Herbst, Dean F. Bajorin, Harry Bleiberg, Diane Blum, Desirée Hao, Bruce E. Johnson, Robert F. Ozols, George D. Demetri, Patricia A. Ganz, Mark G. Kris, Bernard Levin, Maurie Markman, Derek Raghavan, Gregory H. Reaman, Raymond Sawaya, Lynn M. Schuchter, John W. Sweetenham, Linda T. Vahdat, Everett E. Vokes, Rodger J. Winn, and Robert J. Mayer
	JCO Jan 1 2006: 190–205. First published on Dec 2 2005; 10.1200/JCO.2005.04.8678. [Abstract] [Full Text] [PDF]

ART OF ONCOLOGY

The Best Guess Approach to Phase I Trial Design

Daniela D. Rosa, John Harris, and Gordon C. Jayson

JCO Jan 1 2006: 206–208. [Full Text] [PDF]

CORRESPONDENCE
	Prognostic Factors in Human Herpesvirus 8–Related Lymphoproliferative Disorders Associated With HIV Infection
	Cecilia Simonelli, Rosamaria Tedeschi, Annunziata Gloghini, Michele Spina, Renato Talamini, Paolo De Paoli, Umberto Tirelli, and Antonino Carbone
	JCO Jan 1 2006: 209. [Full Text] [PDF]
	In Reply:
	Emmanuelle Boulanger, Laurence Gérard, Eric Oksenhendler, and Félix Agbalika
	JCO Jan 1 2006: 209-a–210. [Full Text] [PDF]
	International Breast Cancer Study Group Trial of Sentinel Node Biopsy
	Viviana Galimberti
	JCO Jan 1 2006: 210–211. [Full Text] [PDF]
	Aneurysmal Bone Cyst: A Neoplasm Driven by Upregulation of the USP6 Oncogene
	Andre M. Oliveira, Margaret M. Chou, Antonio R. Perez-Atayde, and Andrew E. Rosenberg
	JCO Jan 1 2006: e1. [Full Text] [PDF]
	In Reply:
	Henry J. Mankin
	JCO Jan 1 2006: e2. [Full Text] [PDF]
	Flare in Neuropathy Following Rituximab Therapy for Waldenstrom’s Macroglobulinemia
	Vanita Noronha, Thomas M. Fynan, and Thomas Duffy
	JCO Jan 1 2006: e3. [Full Text] [PDF]

ERRATUM

ERRATUM

JCO Jan 1 2006: 212. [Full Text] [PDF]

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