PRESIDENTIAL ADDRESS

ASCO in the 21st Century: Challenges and Opportunities—ASCO Presidential Address 2005

David H. Johnson

JCO May 1 2006: 1967–1971. [Full Text] [PDF]

EDITORIALS

Inherited Genetic Markers and Cancer Outcomes: Personalized Medicine in the Postgenome Era

Timothy R. Rebbeck

JCO May 1 2006: 1972–1974. [Full Text] [PDF]

Exploring Dose-Intensity: Carefully Comparing High-Dose With Low-Dose External-Beam Radiotherapy for Prostate Cancer

Howard M. Sandler

JCO May 1 2006: 1975–1977. [Full Text] [PDF]

Sentinel Lymph Node Histopathology in Breast Cancer: Minimal Disease Versus Artifact

Beverley A. Carter and David L. Page

JCO May 1 2006: 1978–1979. First published on Apr 10 2006; 10.1200/JCO.2006.05.6036. [Full Text] [PDF]

Reponses to Topoisomerase-I Inhibitors in Extensive Small-Cell Lung Cancer: Chance or Chromosomes?

Michael C. Perry

JCO May 1 2006: 1980–1981. [Full Text] [PDF]

ORIGINAL REPORTS
Genitourinary Cancer
	Impact of IGF-I and CYP19 Gene Polymorphisms on the Survival of Patients With Metastatic Prostate Cancer
	Norihiko Tsuchiya, Lizhong Wang, Hiroyoshi Suzuki, Takehiko Segawa, Hisami Fukuda, Shintaro Narita, Masaki Shimbo, Toshiyuki Kamoto, Kenji Mitsumori, Tomohiko Ichikawa, Osamu Ogawa, Akira Nakamura, and Tomonori Habuchi
	JCO May 1 2006: 1982–1989. [Abstract] [Full Text] [PDF]
	Dose-Response in Radiotherapy for Localized Prostate Cancer: Results of the Dutch Multicenter Randomized Phase III Trial Comparing 68 Gy of Radiotherapy With 78 Gy
	Stephanie T.H. Peeters, Wilma D. Heemsbergen, Peter C.M. Koper, Wim L.J. van Putten, Annerie Slot, Michel F.H. Dielwart, Johannes M.G. Bonfrer, Luca Incrocci, and Joos V. Lebesque
	JCO May 1 2006: 1990–1996. [Abstract] [Full Text] [PDF]
	Impact of Immune Parameters on Long-Term Survival in Metastatic Renal Cell Carcinoma
	Frede Donskov and Hans von der Maase
	JCO May 1 2006: 1997–2005. [Abstract] [Full Text] [PDF]
	Mortality After Major Surgery for Urologic Cancers in Specialized Urology Hospitals: Are They Any Better?
	Badrinath R. Konety, Veerasathpurush Allareddy, Sanjukta Modak, and Brian Smith
	JCO May 1 2006: 2006–2012. [Abstract] [Full Text] [PDF]

Breast Cancer
	Axillary Sentinel Lymph Nodes Can Be Falsely Positive Due to Iatrogenic Displacement and Transport of Benign Epithelial Cells in Patients With Breast Carcinoma
	Ira J. Bleiweiss, Chandandeep S. Nagi, and Shabnam Jaffer
	JCO May 1 2006: 2013–2018. First published on Apr 10 2006; 10.1200/JCO.2005.04.7076. [Abstract] [Full Text] [PDF]
	Sequential Preoperative or Postoperative Docetaxel Added to Preoperative Doxorubicin Plus Cyclophosphamide for Operable Breast Cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-27
	Harry D. Bear, Stewart Anderson, Roy E. Smith, Charles E. Geyer, Jr, Eleftherios P. Mamounas, Bernard Fisher, Ann M. Brown, Andre Robidoux, Richard Margolese, Morton S. Kahlenberg, Soonmyung Paik, Atilla Soran, D. Lawrence Wickerham, and Norman Wolmark
	JCO May 1 2006: 2019–2027. First published on Apr 10 2006; 10.1200/JCO.2005.04.1665. [Abstract] [Full Text] [PDF]
	Prognosis After Ipsilateral Breast Tumor Recurrence and Locoregional Recurrences in Five National Surgical Adjuvant Breast and Bowel Project Node-Positive Adjuvant Breast Cancer Trials
	Irene L. Wapnir, Stewart J. Anderson, Eleftherios P. Mamounas, Charles E. Geyer, Jr, Jong-Hyeon Jeong, Elizabeth Tan-Chiu, Bernard Fisher, and Norman Wolmark
	JCO May 1 2006: 2028–2037. [Abstract] [Full Text] [PDF]

Lung Cancer
	Randomized Phase III Trial Comparing Irinotecan/Cisplatin With Etoposide/Cisplatin in Patients With Previously Untreated Extensive-Stage Disease Small-Cell Lung Cancer
	Nasser Hanna, Paul A. Bunn, Jr, Corey Langer, Lawrence Einhorn, Troy Guthrie, Jr, Thaddeus Beck, Rafat Ansari, Peter Ellis, Michael Byrne, Mark Morrison, Subramanian Hariharan, Benjamin Wang, and Alan Sandler
	JCO May 1 2006: 2038–2043. [Abstract] [Full Text] [PDF]
	Open-Label, Multicenter, Randomized, Phase III Study Comparing Oral Topotecan/Cisplatin Versus Etoposide/Cisplatin As Treatment for Chemotherapy-Naive Patients With Extensive-Disease Small-Cell Lung Cancer
	John R. Eckardt, Joachim von Pawel, Zsolt Papai, Antoaneta Tomova, Valentina Tzekova, Theresa E. Crofts, Sarah Brannon, Paul Wissel, and Graham Ross
	JCO May 1 2006: 2044–2051. [Abstract] [Full Text] [PDF]

Clinical Trials
	Phase I, Pharmacokinetic, and Pharmacodynamic Study of Intravenously Administered Ad5CMV-p53, an Adenoviral Vector Containing the Wild-Type p53 Gene, in Patients With Advanced Cancer
	Anthony W. Tolcher, Desiree Hao, Johann de Bono, Alex Miller, Amita Patnaik, Lisa A. Hammond, Leslie Smetzer, Jill Van Wart Hood, James Merritt, Eric K. Rowinsky, Chris Takimoto, Dan Von Hoff, and S. Gail Eckhardt
	JCO May 1 2006: 2052–2058. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Oral Uracil and Tegafur Plus Leucovorin Compared With Intravenous Fluorouracil and Leucovorin in Stage II and III Carcinoma of the Colon: Results From National Surgical Adjuvant Breast and Bowel Project Protocol C-06
	Barry C. Lembersky, H. Samuel Wieand, Nicholas J. Petrelli, Michael J. O'Connell, Linda H. Colangelo, Roy E. Smith, Thomas E. Seay, Jeffrey K. Giguere, M. Ernest Marshall, Andrew D. Jacobs, Lauren K. Colman, Atilla Soran, Greg Yothers, and Norman Wolmark
	JCO May 1 2006: 2059–2064. [Abstract] [Full Text] [PDF]
	Chemotherapy Regimen Predicts Steatohepatitis and an Increase in 90-Day Mortality After Surgery for Hepatic Colorectal Metastases
	Jean-Nicolas Vauthey, Timothy M. Pawlik, Dario Ribero, Tsung-Teh Wu, Daria Zorzi, Paulo M. Hoff, Henry Q. Xiong, Cathy Eng, Gregory Y. Lauwers, Mari Mino-Kenudson, Mauro Risio, Andrea Muratore, Lorenzo Capussotti, Steven A. Curley, and Eddie K. Abdalla
	JCO May 1 2006: 2065–2072. [Abstract] [Full Text] [PDF]

Palliative Care
	Patient-Controlled Methylphenidate for Cancer Fatigue: A Double-Blind, Randomized, Placebo-Controlled Trial
	Eduardo Bruera, Vicente Valero, Larry Driver, Loren Shen, Jie Willey, Tao Zhang, and J. Lynn Palmer
	JCO May 1 2006: 2073–2078. [Abstract] [Full Text] [PDF]

Neurooncology
	Response of Asymptomatic Brain Metastases From Small-Cell Lung Cancer to Systemic First-Line Chemotherapy
	Tatjana Seute, Pieter Leffers, Jan T. Wilmink, Guul P.M. ten Velde, and Albert Twijnstra
	JCO May 1 2006: 2079–2083. [Abstract] [Full Text] [PDF]
	Changes in Neurologic Function Tests May Predict Neurotoxicity Caused by Ixabepilone
	James J. Lee, Jennifer A. Low, Earllaine Croarkin, Rebecca Parks, Arlene W. Berman, Nitin Mannan, Seth M. Steinberg, and Sandra M. Swain
	JCO May 1 2006: 2084–2091. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Phase III Trial of an Emulsion Containing Trolamine for the Prevention of Radiation Dermatitis in Patients With Advanced Squamous Cell Carcinoma of the Head and Neck: Results of Radiation Therapy Oncology Group Trial 99-13
	Elizabeth A. Elliott, James R. Wright, R. Suzanne Swann, Felix Nguyen-Tân, Cristiane Takita, M. Kara Bucci, Adam S. Garden, Harold Kim, Eugen B. Hug, Janice Ryu, Michael Greenberg, Jerrold P. Saxton, Kian Ang, and Lawrence Berk
	JCO May 1 2006: 2092–2097. [Abstract] [Full Text] [PDF]
	Prognostic Significance of [18F]-Misonidazole Positron Emission Tomography–Detected Tumor Hypoxia in Patients With Advanced Head and Neck Cancer Randomly Assigned to Chemoradiation With or Without Tirapazamine: A Substudy of Trans-Tasman Radiation Oncology Group Study 98.02
	Danny Rischin, Rodney J. Hicks, Richard Fisher, David Binns, June Corry, Sandro Porceddu, and Lester J. Peters
	JCO May 1 2006: 2098–2104. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Bortezomib Therapy in Patients With Relapsed or Refractory Lymphoma: Potential Correlation of In Vitro Sensitivity and Tumor Necrosis Factor Alpha Response With Clinical Activity
	Sandra J. Strauss, Lenushka Maharaj, Susan Hoare, Peter W. Johnson, John A. Radford, Sarah Vinnecombe, Lynda Millard, Ama Rohatiner, Anthony Boral, Elizabeth Trehu, David Schenkein, Frances Balkwill, Simon P. Joel, and T. Andrew Lister
	JCO May 1 2006: 2105–2112. First published on Apr 10 2006; 10.1200/JCO.2005.04.6789. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Prognosis and Management of Patients With Node-Negative Invasive Breast Carcinoma That Is 1 cm or Smaller in Size (stage 1; T1a,bN0M0): A Review of the Literature
	Emer O. Hanrahan, Vicente Valero, Ana M. Gonzalez-Angulo, and Gabriel N. Hortobagyi
	JCO May 1 2006: 2113–2122. [Abstract] [Full Text] [PDF]

ART OF ONCOLOGY

The Attorney As the Newest Member of the Cancer Treatment Team

Stewart B. Fleishman, Randye Retkin, Julie Brandfield, and Victoria Braun

JCO May 1 2006: 2123–2126. [Full Text] [PDF]

CORRESPONDENCE
	A Call for Clinical Trials: Lipophilic Statins May Prove Effective in Treatment and Prevention of Particular Breast Cancer Subtypes
	Anjali S. Kumar, Michael Campbell, Christopher C. Benz, and Laura J. Esserman
	JCO May 1 2006: 2127. [Full Text] [PDF]
	In Reply
	Stefanos Bonovas, Kalitsa Filioussi, Nikolaos Tsavaris, and Nikolaos M. Sitaras
	JCO May 1 2006: 2127-a–2128. [Full Text] [PDF]
	Lipophilic Statins Merit Additional Study for Breast Cancer Chemoprevention
	Tatiana M. Prowell, Vered Stearns, and Bruce Trock
	JCO May 1 2006: 2128–2129. [Full Text] [PDF]
	In Reply
	Stefanos Bonovas, Kalitsa Filioussi, Nikolaos Tsavaris, and Nikolaos M. Sitaras
	JCO May 1 2006: 2129. [Full Text] [PDF]
	Statins and Breast Cancer Prevention: Time for Randomized Controlled Trials
	Julian R. Sprague and Marie E. Wood
	JCO May 1 2006: 2129-a–2130. [Full Text] [PDF]
	In Reply
	Stefanos Bonovas, Kalitsa Filioussi, Nikolaos Tsavaris, and Nikolaos M. Sitaras
	JCO May 1 2006: 2130–2131. [Full Text] [PDF]
	Decisional Priority in Pediatric Oncology Revisited: Involving Children in Decision Making
	Nicolas André
	JCO May 1 2006: 2131. [Full Text] [PDF]
	In Reply
	Simon N. Whitney, Stacey L. Berg, Angela M. Ethier, Ernest Frugé, Laurence B. McCullough, and Marilyn Hockenberry
	JCO May 1 2006: 2131-a–2132. [Full Text] [PDF]
	Hand-Foot Syndrome After Dose-Dense Adjuvant Chemotherapy for Breast Cancer: A Case Series
	Aditya Bardia, Charles L. Loprinzi, and Matthew P. Goetz
	JCO May 1 2006: e18–19. [Full Text] [PDF]
	Treatment of Metastatic Renal Cell Carcinoma With Autologous T-Lymphocytes Genetically Retargeted Against Carbonic Anhydrase IX: First Clinical Experience
	Cor H.J. Lamers, Stefan Sleijfer, Arnold G. Vulto, Wim H.J. Kruit, Mike Kliffen, Reno Debets, Jan W. Gratama, Gerrit Stoter, and Egbert Oosterwijk
	JCO May 1 2006: e20–22. [Full Text] [PDF]

ERRATA

ERRATUM

JCO May 1 2006: 2133. [Full Text] [PDF]

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