EDITORIALS

Irinogenetics: What Is the Right Star?

Federico Innocenti, Everett E. Vokes, and Mark J. Ratain

JCO May 20 2006: 2221–2224. First published on Apr 24 2006; 10.1200/JCO.2005.05.2464. [Full Text] [PDF]

Is There a Role for the Irreversible Epidermal Growth Factor Receptor Inhibitor EKB-569 in the Treatment of Cancer? A Mutation-Driven Question

Jose Baselga

JCO May 20 2006: 2225–2226. [Full Text] [PDF]

A "Bone" Fide Predictor of Metastasis? Predicting Breast Cancer Metastasis to Bone

Scott L. Kominsky and Nancy E. Davidson

JCO May 20 2006: 2227–2229. First published on Apr 24 2006; 10.1200/JCO.2005.05.5319. [Full Text] [PDF]

Is Tumor Immunity the Same Thing As Autoimmunity? Implications for Cancer Immunotherapy

Howard L. Kaufman and Jedd D. Wolchok

JCO May 20 2006: 2230–2232. [Full Text] [PDF]

Epoetin Alfa and Darbepoetin Alfa Go Head to Head

David P. Steensma and Charles L. Loprinzi

JCO May 20 2006: 2233–2236. [Full Text] [PDF]

ORIGINAL REPORTS
Lung Cancer
	Comprehensive Analysis of UGT1A Polymorphisms Predictive for Pharmacokinetics and Treatment Outcome in Patients With Non–Small-Cell Lung Cancer Treated With Irinotecan and Cisplatin
	Ji-Youn Han, Hyeong-Seok Lim, Eun Soon Shin, Yeon-Kyeong Yoo, Yong Hoon Park, Jong-Eun Lee, In-Jin Jang, Dae Ho Lee, and Jin Soo Lee
	JCO May 20 2006: 2237–2244. First published on Apr 24 2006; 10.1200/JCO.2005.03.0239. [Abstract] [Full Text] [PDF]
	Never-Smokers With Lung Cancer: Epidemiologic Evidence of a Distinct Disease Entity
	Chee-Keong Toh, Fei Gao, Wan-Teck Lim, Swan-Swan Leong, Kam-Weng Fong, Swee-Peng Yap, Anne A.L. Hsu, Philip Eng, Heng-Nung Koong, Agasthian Thirugnanam, and Eng-Huat Tan
	JCO May 20 2006: 2245–2251. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I Study of EKB-569, an Irreversible Inhibitor of the Epidermal Growth Factor Receptor, in Patients With Advanced Solid Tumors
	Charles Erlichman, Manuel Hidalgo, Joseph P. Boni, Patricia Martins, Susan E. Quinn, Charles Zacharchuk, Peter Amorusi, Alex A. Adjei, and Eric K. Rowinsky
	JCO May 20 2006: 2252–2260. [Abstract] [Full Text] [PDF]

Breast Cancer
	Genes Associated With Breast Cancer Metastatic to Bone
	Marcel Smid, Yixin Wang, Jan G.M. Klijn, Anieta M. Sieuwerts, Yi Zhang, David Atkins, John W.M. Martens, and John A. Foekens
	JCO May 20 2006: 2261–2267. First published on Apr 24 2006; 10.1200/JCO.2005.03.8802. [Abstract] [Full Text] [PDF]
	Study of Failure Pattern Among High-Risk Breast Cancer Patients With or Without Postmastectomy Radiotherapy in Addition to Adjuvant Systemic Therapy: Long-Term Results From the Danish Breast Cancer Cooperative Group DBCG 82 b and c Randomized Studies
	Hanne M. Nielsen, Marie Overgaard, Cai Grau, Anni R. Jensen, and Jens Overgaard
	JCO May 20 2006: 2268–2275. First published on Apr 17 2006; 10.1200/JCO.2005.02.8738. [Abstract] [Full Text] [PDF] [Publisher's Note]
	Indium-111–Labeled Trastuzumab Scintigraphy in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer
	Patrick J. Perik, Marjolijn N. Lub-De Hooge, Jourik A. Gietema, Winette T.A. van der Graaf, M. Alexander de Korte, Sharon Jonkman, Jos G.W. Kosterink, Dirk J. van Veldhuisen, Dirk T. Sleijfer, Pieter L. Jager, and Elisabeth G.E. de Vries
	JCO May 20 2006: 2276–2282. [Abstract] [Full Text] [PDF]

Treatment-Related Complications
	Enterocolitis in Patients With Cancer After Antibody Blockade of Cytotoxic T-Lymphocyte–Associated Antigen 4
	Kimberly E. Beck, Joseph A. Blansfield, Khoi Q. Tran, Andrew L. Feldman, Marybeth S. Hughes, Richard E. Royal, Udai S. Kammula, Suzanne L. Topalian, Richard M. Sherry, David Kleiner, Martha Quezado, Israel Lowy, Michael Yellin, Steven A. Rosenberg, and James C. Yang
	JCO May 20 2006: 2283–2289. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Randomized Comparison of Every-2-Week Darbepoetin Alfa and Weekly Epoetin Alfa for the Treatment of Chemotherapy-Induced Anemia: The 20030125 Study Group Trial
	John Glaspy, Saroj Vadhan-Raj, Ravi Patel, Linda Bosserman, Eddie Hu, Richard E. Lloyd, Ralph V. Boccia, Dianne Tomita, and Greg Rossi
	JCO May 20 2006: 2290–2297. [Abstract] [Full Text] [PDF]
	Geriatric Syndromes in Elderly Patients Admitted to an Oncology–Acute Care for Elders Unit
	Kellie L. Flood, Maria B. Carroll, Cyndi V. Le, Linda Ball, Debbie A. Esker, and David B. Carr
	JCO May 20 2006: 2298–2303. [Abstract] [Full Text] [PDF]
	Comorbidity, Disability, and Geriatric Syndromes in Elderly Cancer Patients Receiving Home Health Care
	Siran M. Koroukian, Patrick Murray, and Elizabeth Madigan
	JCO May 20 2006: 2304–2310. [Abstract] [Full Text] [PDF]
	Physical and Emotional Health Effects and Social Consequences After Participation in a Low-Fat, High-Carbohydrate Dietary Trial for More Than 5 Years
	T. Gregory Hislop, Chris D. Bajdik, Lynda G. Balneaves, Andrea Holmes, Selina Chan, Evelyn Wu, Zenaida U. Abanto, and Andrea L. Butler
	JCO May 20 2006: 2311–2317. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Radiochemotherapy After Transurethral Resection for High-Risk T1 Bladder Cancer: An Alternative to Intravesical Therapy or Early Cystectomy?
	Christian Weiss, Carolin Wolze, Dirk Gerhard Engehausen, Oliver J. Ott, Frens S. Krause, Karl-Michael Schrott, Jürgen Dunst, Rolf Sauer, and Claus Rödel
	JCO May 20 2006: 2318–2324. [Abstract] [Full Text] [PDF]

Sarcomas
	Surgical Management of Advanced Gastrointestinal Stromal Tumors After Treatment With Targeted Systemic Therapy Using Kinase Inhibitors
	Chandrajit P. Raut, Matthew Posner, Jayesh Desai, Jeffrey A. Morgan, Suzanne George, David Zahrieh, Christopher D.M. Fletcher, George D. Demetri, and Monica M. Bertagnolli
	JCO May 20 2006: 2325–2331. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Prognostic Significance of Blasts in the Cerebrospinal Fluid Without Pleiocytosis or a Traumatic Lumbar Puncture in Children With Acute Lymphoblastic Leukemia: Experience of the Dutch Childhood Oncology Group
	D. Maroeska W.M. te Loo, Willem A. Kamps, Anna van der Does-van den Berg, Elisabeth R. van Wering, and Siebold S.N. de Graaf
	JCO May 20 2006: 2332–2336. [Abstract] [Full Text] [PDF]
	Alemtuzumab As Consolidation After a Response to Fludarabine Is Effective in Purging Residual Disease in Patients With Chronic Lymphocytic Leukemia
	Marco Montillo, Alessandra Tedeschi, Sara Miqueleiz, Silvio Veronese, Roberto Cairoli, Liliana Intropido, Francesca Ricci, Anna Colosimo, Barbara Scarpati, Michela Montagna, Michele Nichelatti, Mario Regazzi, and Enrica Morra
	JCO May 20 2006: 2337–2342. First published on Apr 17 2006; 10.1200/JCO.2005.04.6037. [Abstract] [Full Text] [PDF]
	Clinical Outcomes and Prognostic Factors in Patients With Richter's Syndrome Treated With Chemotherapy or Chemoimmunotherapy With or Without Stem-Cell Transplantation
	Apostolia-Maria Tsimberidou, Susan O'Brien, Issa Khouri, Francis J. Giles, Hagop M. Kantarjian, Richard Champlin, Sijin Wen, Kim-Anh Do, Susan C. Smith, Susan Lerner, Emil J. Freireich, and Michael J. Keating.
	JCO May 20 2006: 2343–2351. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Treatment of Anaplastic Histology Wilms' Tumor: Results From the Fifth National Wilms' Tumor Study
	Jeffrey S. Dome, Cecilia A. Cotton, Elizabeth J. Perlman, Norman E. Breslow, John A. Kalapurakal, Michael L. Ritchey, Paul E. Grundy, Marcio Malogolowkin, J. Bruce Beckwith, Robert C. Shamberger, Gerald M. Haase, Max J. Coppes, Peter Coccia, Morris Kletzel, Robert M. Weetman, Milton Donaldson, Roger M. Macklis, and Daniel M. Green
	JCO May 20 2006: 2352–2358. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Immunohistochemical Test for MLH1 and MSH2 Expression Predicts Clinical Outcome in Stage II and III Colorectal Cancer Patients
	Giovanni Lanza, Roberta Gafà, Alessandra Santini, Iva Maestri, Laura Guerzoni, and Luigi Cavazzini
	JCO May 20 2006: 2359–2367. [Abstract] [Full Text] [PDF]
	Duration of Adjuvant Chemotherapy for Colon Cancer and Survival Among the Elderly
	Alfred I. Neugut, Matthew Matasar, Xiaoyan Wang, Russell McBride, Judith S. Jacobson, Wei-Yann Tsai, Victor R. Grann, and Dawn L. Hershman
	JCO May 20 2006: 2368–2375. First published on Apr 17 2006; 10.1200/JCO.2005.04.5005. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	HER-2 Is an Independent Prognostic Factor in Endometrial Cancer: Association With Outcome in a Large Cohort of Surgically Staged Patients
	Carl Morrison, Vanna Zanagnolo, Nilsa Ramirez, David E. Cohn, Nicole Kelbick, Larry Copeland, Larry G. Maxwell, and Jeffrey M. Fowler
	JCO May 20 2006: 2376–2385. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Metachronous Intracranial Germinoma in a Patient With a Previous Primary Mediastinal Seminoma

Pablo M. Bedano, Jose Bonnin, and Lawrence H. Einhorn

JCO May 20 2006: 2386–2387. [Full Text] [PDF]

Intravascular Hemolysis As a Complication of Clostridium Perfringens Sepsis

Heather L. McArthur, Bakul I. Dalal, and Christian Kollmannsberger

JCO May 20 2006: 2387–2388. [Full Text] [PDF]

Paraneoplastic Erythropoietin-Induced Polycythemia Associated With Small Lymphocytic Lymphoma

Abdulwahab J. Al-Tourah, Peter W.K. Tsang, Brian F. Skinnider, and Paul J. Hoskins

JCO May 20 2006: 2388–2389. [Full Text] [PDF]

Tumor Lysis Syndrome After Treatment With Docetaxel for Non–Small-Cell Lung Cancer

Daniel Ajzensztejn, Vinayak S. Hegde, and Siow Ming Lee

JCO May 20 2006: 2389–2391. [Full Text] [PDF]

CORRESPONDENCE

Effect of Tamoxifen After Chemotherapy in Hormone Receptor–Positive, Node-Negative Breast Cancer

Lawrence C. Panasci

JCO May 20 2006: 2392. [Full Text] [PDF]

In Reply:

Laura F. Hutchins and Stephanie J. Green

JCO May 20 2006: 2392-a. [Full Text] [PDF]

Myeloid Toxicity in Breast Cancer Patients Receiving Adjuvant Chemotherapy With Pegfilgrastim Support

Antonio C. Wolff, Richard J. Jones, Nancy E. Davidson, Stacie C. Jeter, and Vered Stearns

JCO May 20 2006: 2392-b–2394. [Full Text] [PDF]

In Reply:

Harold J. Burstein

JCO May 20 2006: 2394–2395. [Full Text] [PDF]

Aggressive Surgery and Ovarian Cancer

Dennis S. Chi and Richard R. Barakat

JCO May 20 2006: 2395–2396. [Full Text] [PDF]

In Reply:

Simon C. Crawford, Jim Paul, Stan B. Kaye, Paul A. Vasey, Jo A. Davis, and Andrea Hay

JCO May 20 2006: 2396–2397. [Full Text] [PDF]

Importance of Surgical Aggressiveness in Advanced Ovarian Cancer

Giovanni D. Aletti and William A. Cliby

JCO May 20 2006: 2397. [Full Text] [PDF]

In Reply:

Simon C. Crawford, Jim Paul, Stan B. Kaye, Paul A. Vasey, Jo A. Davis, and Andrea Hay

JCO May 20 2006: 2398–2399. [Full Text] [PDF]

Acute Chemotherapy-Induced Cardiovascular Changes in Patients With Testicular Cancer: Are There Implications for Blood Pressure Management in Patients Receiving Chemotherapy?

Sadhna Kohli and Manish Kohli

JCO May 20 2006: 2399. [Full Text] [PDF]

In Reply:

Esther C. de Haas, Janine Nuver, Andries J. Smit, Dirk Th. Sleijfer, and Jourik A. Gietema

JCO May 20 2006: 2399-a–2400. [Full Text] [PDF]

ERRATUM

ERRATUM

JCO May 20 2006: 2401–2403. [Full Text] [PDF]

EXPRESSIONS OF CONCERN

EXPRESSION OF CONCERN

JCO May 20 2006: 2404. [Full Text] [PDF] [Investigating Committee Report]

EXPRESSION OF CONCERN

JCO May 20 2006: 2404-a. [Full Text] [PDF] [Investigating Committee Report]

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