EDITORIALS

Prognostic Markers of Local Relapse in Rectal Cancer: Are We Any Further Forward?

Patrick G. Johnston

JCO Sep 1 2006: 4049–4050. [Full Text] [PDF]

Thymidine Phosphorylase and Capecitabine: A Predictive Marker for Therapy Selection?

Bert H. O'Neil and Howard L. McLeod

JCO Sep 1 2006: 4051–4053. [Full Text] [PDF]

What Is the Right Dose? The Elusive Optimal Biologic Dose in Phase I Clinical Trials

Alex A. Adjei

JCO Sep 1 2006: 4054–4055. [Full Text] [PDF]

Heart of Darkness: The Downside of Trastuzumab

Daniel F. Hayes and Michael H. Picard

JCO Sep 1 2006: 4056–4058. First published on Aug 14 2006; 10.1200/JCO.2006.07.5143. [Full Text] [PDF]

Which Breast Cancer Patients Should Really Worry About Radiation-Induced Heart Disease—And How Much?

Abram Recht

JCO Sep 1 2006: 4059–4061. First published on Aug 14 2006; 10.1200/JCO.2006.07.7909. [Full Text] [PDF]

ORIGINAL REPORTS
Gastrointestinal Cancer
	Lymph Node Status and TS Gene Expression Are Prognostic Markers in Stage II/III Rectal Cancer After Neoadjuvant Fluorouracil-Based Chemoradiotherapy
	Torsten Liersch, Claus Langer, B. Michael Ghadimi, Bettina Kulle, Daniela E. Aust, Gustavo B. Baretton, Wolfgang Schwabe, Peter Häusler, Heinz Becker, and Christiane Jakob
	JCO Sep 1 2006: 4062–4068. [Abstract] [Full Text] [PDF]
	Thymidine Phosphorylase Expression Is Associated With Response to Capecitabine Plus Irinotecan in Patients With Metastatic Colorectal Cancer
	Neal J. Meropol, Philip J. Gold, Robert B. Diasio, Michael Andria, Mandeep Dhami, Thomas Godfrey, Albert J. Kovatich, Kirk A. Lund, Edith Mitchell, and Roland Schwarting
	JCO Sep 1 2006: 4069–4077. [Abstract] [Full Text] [PDF]
	Predictors of Recurrence in Patients With T2 and Early T3, N0 Adenocarcinoma of the Rectum Treated by Surgery Alone
	Aviram Nissan, Alexander Stojadinovic, Jinru Shia, Axel Hoos, Jose G. Guillem, David Klimstra, Alfred M. Cohen, Bruce D. Minsky, Philip B. Paty, and W. Douglas Wong
	JCO Sep 1 2006: 4078–4084. [Abstract] [Full Text] [PDF]
	Pooled Analysis of Safety and Efficacy of Oxaliplatin Plus Fluorouracil/Leucovorin Administered Bimonthly in Elderly Patients With Colorectal Cancer
	Richard M. Goldberg, Isabelle Tabah-Fisch, Harry Bleiberg, Aimery de Gramont, Christophe Tournigand, Thierry Andre, Mace L. Rothenberg, Erin Green, and Daniel J. Sargent
	JCO Sep 1 2006: 4085–4091. [Abstract] [Full Text] [PDF] [Publisher's Note]

Phase I and Clinical Pharmacology
	Phase I Dose Escalation and Pharmacokinetic Study of Enzastaurin, an Oral Protein Kinase C Beta Inhibitor, in Patients With Advanced Cancer
	Michael A. Carducci, Luna Musib, Merrill S. Kies, Roberto Pili, Mylene Truong, Julie R. Brahmer, Patricia Cole, Rana Sullivan, Jeanne Riddle, Jill Schmidt, Nathan Enas, Vikram Sinha, Donald E. Thornton, and Roy S. Herbst
	JCO Sep 1 2006: 4092–4099. [Abstract] [Full Text] [PDF]

Breast Cancer
	Late Cardiac Mortality and Morbidity in Early-Stage Breast Cancer Patients After Breast-Conservation Treatment
	Eleanor E.R. Harris, Candace Correa, Wei-Ting Hwang, Jessica Liao, Harold I. Litt, Victor A. Ferrari, and Lawrence J. Solin
	JCO Sep 1 2006: 4100–4106. First published on Aug 14 2006; 10.1200/JCO.2005.05.1037. [Abstract] [Full Text] [PDF]
	Long-Term Cardiac Tolerability of Trastuzumab in Metastatic Breast Cancer: The M.D. Anderson Cancer Center Experience
	Valentina Guarneri, Daniel J. Lenihan, Vicente Valero, Jean-Bernard Durand, Kristine Broglio, Kenneth R. Hess, Laura Boehnke Michaud, Ana M. Gonzalez-Angulo, Gabriel N. Hortobagyi, and Francisco J. Esteva
	JCO Sep 1 2006: 4107–4115. First published on Aug 14 2006; 10.1200/JCO.2005.04.9551. [Abstract] [Full Text] [PDF] [Publisher's Note]

Cost Effectiveness
	Cost-Effectiveness Analysis of Computerized Tomography in the Routine Follow-Up of Patients After Primary Treatment for Hodgkin’s Disease
	Beverly A. Guadagnolo, Rinaa S. Punglia, Karen M. Kuntz, Peter M. Mauch, and Andrea K. Ng
	JCO Sep 1 2006: 4116–4122. [Abstract] [Full Text] [PDF]

AIDS-Related Cancer
	Phase II Trial of CHOP Plus Rituximab in Patients With HIV-Associated Non-Hodgkin's Lymphoma
	François Boué, Jean Gabarre, Christian Gisselbrecht, Jacques Reynes, Antoine Cheret, Fabrice Bonnet, Eric Billaud, Martine Raphael, Remi Lancar, and Dominique Costagliola
	JCO Sep 1 2006: 4123–4128. First published on Aug 8 2006; 10.1200/JCO.2005.05.4684. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Outpatient Oral Antibiotics for Febrile Neutropenic Cancer Patients Using a Score Predictive for Complications
	Jean Klastersky, Marianne Paesmans, Aspasia Georgala, Frédérique Muanza, Barbara Plehiers, Laurent Dubreucq, Yassine Lalami, Michel Aoun, and Martine Barette
	JCO Sep 1 2006: 4129–4134. [Abstract] [Full Text] [PDF] [Polish PDF]

Hematologic Malignancies
	Prognostic Impact of Germinal Center–Associated Proteins and Chromosomal Breakpoints in Poor-Risk Diffuse Large B-Cell Lymphoma
	Gustaaf W. van Imhoff, Evert-Jan G. Boerma, Bronno van der Holt, Ed Schuuring, Leo F. Verdonck, Hanneke C. Kluin-Nelemans, and Philip M. Kluin
	JCO Sep 1 2006: 4135–4142. [Abstract] [Full Text] [PDF]
	Phase II Trial of CHOP Chemotherapy Followed by Tositumomab/Iodine I-131 Tositumomab for Previously Untreated Follicular Non-Hodgkin's Lymphoma: Five-Year Follow-Up of Southwest Oncology Group Protocol S9911
	Oliver W. Press, Joseph M. Unger, Rita M. Braziel, David G. Maloney, Thomas P. Miller, Michael LeBlanc, and Richard I. Fisher
	JCO Sep 1 2006: 4143–4149. First published on Aug 8 2006; 10.1200/JCO.2006.05.8198. [Abstract] [Full Text] [PDF]

Bone Marrow Transplantation
	Factors Associated With Outcomes in Allogeneic Hematopoietic Cell Transplantation With Nonmyeloablative Conditioning After Failed Myeloablative Hematopoietic Cell Transplantation
	Frédéric Baron, Rainer Storb, Barry E. Storer, Michael B. Maris, Dietger Niederwieser, Judith A. Shizuru, Thomas R. Chauncey, Benedetto Bruno, Stephen J. Forman, Peter A. McSweeney, Richard T. Maziarz, Michael A. Pulsipher, Edward D. Agura, James Wade, Mohamed Sorror, David G. Maloney, and Brenda M. Sandmaier
	JCO Sep 1 2006: 4150–4157. First published on Aug 8 2006; 10.1200/JCO.2006.06.9914. [Abstract] [Full Text] [PDF]

Clinical Trials
	Impact of a Multi-Disciplinary Patient Education Session on Accrual to a Difficult Clinical Trial: The Toronto Experience With the Surgical Prostatectomy Versus Interstitial Radiation Intervention Trial
	Kris Wallace, Neil Fleshner, Michael Jewett, Joan Basiuk, and Juanita Crook
	JCO Sep 1 2006: 4158–4162. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Phase I/II Study of Docetaxel, Cisplatin, and Concomitant Boost Radiation for Locally Advanced Squamous Cell Cancer of the Head and Neck
	Anne S. Tsao, Adam S. Garden, Merrill S. Kies, William Morrison, Lei Feng, J. Jack Lee, Fadlo Khuri, Ralph Zinner, Jeffery Myers, Vassiliki Papadimitrakopoulou, Jan Lewin, Gary L. Clayman, K. Kian Ang, and Bonnie S. Glisson
	JCO Sep 1 2006: 4163–4169. [Abstract] [Full Text] [PDF]
	Increased Epidermal Growth Factor Receptor Gene Copy Number Is Associated With Poor Prognosis in Head and Neck Squamous Cell Carcinomas
	Christine H. Chung, Kim Ely, Loris McGavran, Marileila Varella-Garcia, Joel Parker, Natalie Parker, Carolyn Jarrett, Jesse Carter, Barbara A. Murphy, James Netterville, Brian B. Burkey, Robert Sinard, Anthony Cmelak, Shawn Levy, Wendell G. Yarbrough, Robbert J.C. Slebos, and Fred R. Hirsch
	JCO Sep 1 2006: 4170–4176. [Abstract] [Full Text] [PDF] [Supplementary Data]
	Disadvantage of Men Living Alone Participating in Radiation Therapy Oncology Group Head and Neck Trials
	Andre A. Konski, Thomas F. Pajak, Benjamin Movsas, James Coyne, Jonathan Harris, Clement Gwede, Adam Garden, Sharon Spencer, Christopher Jones, and Deborah Watkins-Bruner
	JCO Sep 1 2006: 4177–4183. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Risk of Cardiovascular Mortality in Prostate Cancer Patients in the Rotterdam Randomized Screening Trial
	Suzie J. Otto, Fritz H. Schröder, and Harry J. de Koning
	JCO Sep 1 2006: 4184–4189. [Abstract] [Full Text] [PDF]
	Six-Month Androgen Suppression Plus Radiation Therapy Compared With Radiation Therapy Alone for Men With Prostate Cancer and a Rapidly Increasing Pretreatment Prostate-Specific Antigen Level
	Anthony V. D'Amico, Marian Loffredo, Andrew A. Renshaw, Brittany Loffredo, and Ming-Hui Chen
	JCO Sep 1 2006: 4190–4195. [Abstract] [Full Text] [PDF]

Melanoma
	Randomized Multicenter Trial of Hyperthermic Isolated Limb Perfusion With Melphalan Alone Compared With Melphalan Plus Tumor Necrosis Factor: American College of Surgeons Oncology Group Trial Z0020
	Wendy R. Cornett, Linda M. McCall, Rebecca P. Petersen, Merrick I. Ross, Henry A. Briele, R. Dirk Noyes, Jeffrey J. Sussman, William G. Kraybill, John M. Kane, III, H. Richard Alexander, Jeffrey E. Lee, Paul F. Mansfield, James F. Pingpank, David J. Winchester, Richard L. White, Jr, Vijaya Chadaram, James E. Herndon, II, Douglas L. Fraker, and Douglas S. Tyler
	JCO Sep 1 2006: 4196–4201. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Phase III Study of Craniospinal Radiation Therapy Followed by Adjuvant Chemotherapy for Newly Diagnosed Average-Risk Medulloblastoma
	Roger J. Packer, Amar Gajjar, Gilbert Vezina, Lucy Rorke-Adams, Peter C. Burger, Patricia L. Robertson, Lisa Bayer, Deborah LaFond, Bernadine R. Donahue, MaryAnne H. Marymont, Karin Muraszko, James Langston, and Richard Sposto
	JCO Sep 1 2006: 4202–4208. [Abstract] [Full Text] [PDF]

ART OF ONCOLOGY

Discussing Prognosis: "How Much Do You Want to Know?" Talking to Patients Who Are Prepared for Explicit Information

Anthony L. Back and Robert M. Arnold

JCO Sep 1 2006: 4209–4213. [Full Text] [PDF]

Discussing Prognosis: "How Much Do You Want to Know?" Talking to Patients Who Do Not Want Information or Who Are Ambivalent

Anthony L. Back and Robert M. Arnold

JCO Sep 1 2006: 4214–4217. [Full Text] [PDF]

CORRESPONDENCE
	Immunotherapy and Prognostic Factors
	Luca A. Fumagalli and Fernando Brivio
	JCO Sep 1 2006: 4218–4219. [Full Text] [PDF]
	In Reply
	Frede Donskov and Hans von der Maase
	JCO Sep 1 2006: 4219–4220. [Full Text] [PDF]
	Fertility Preservation Strategies for Breast Cancer Patients
	Lucia Del Mastro and Marco Venturini
	JCO Sep 1 2006: 4220–4221. [Full Text] [PDF]
	In Reply
	Kutluk H. Oktay and Stephanie J. Lee
	JCO Sep 1 2006: 4221–4222. [Full Text] [PDF]
	Sedation and Expertise in Palliative Care
	José António Ferraz Gonçalves
	JCO Sep 1 2006: e44–45. [Full Text] [PDF]
	Epoetin Versus Darbepoetin Conundrum Compromise
	Archie Bleyer
	JCO Sep 1 2006: e46. [Full Text] [PDF]

ERRATA

ERRATUM

JCO Sep 1 2006: 4223. [Full Text] [PDF]

ERRATUM

JCO Sep 1 2006: 4223-a. [Full Text] [PDF]

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