EDITORIALS

Ixabepilone and the Narrow Path to Developing New Cytotoxic Drugs

Luca Gianni

JCO Aug 10 2007: 3389–3391. First published on Jul 2 2007; 10.1200/JCO.2007.10.9504. [Full Text] [PDF]

A Renewed Call for Equipoise

Neal J. Meropol

JCO Aug 10 2007: 3392–3394. [Full Text] [PDF]

Can Statins Pass the Aspirin Litmus Test in Cancer?

John Kauh and Fadlo R. Khuri

JCO Aug 10 2007: 3395–3396. [Full Text] [PDF]

COMMENTS AND CONTROVERSIES

The Value Meal: How to Save $1,700 Per Month or More on Lapatinib

Mark J. Ratain and Ezra E. Cohen

JCO Aug 10 2007: 3397–3398. First published on Jul 16 2007; 10.1200/JCO.2007.12.0758. [Full Text] [PDF]

ORIGINAL REPORTS
Breast Cancer
	Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, in Patients With Taxane-Resistant Metastatic Breast Cancer
	Eva Thomas, Josep Tabernero, Monica Fornier, Pierfranco Conté, Pierre Fumoleau, Ana Lluch, Linda T. Vahdat, Craig A. Bunnell, Howard A. Burris, Patrice Viens, José Baselga, Edgardo Rivera, Valentina Guarneri, Valerie Poulart, Judith Klimovsky, David Lebwohl, and Miguel Martin
	JCO Aug 10 2007: 3399–3406. First published on Jul 2 2007; 10.1200/JCO.2006.08.9102. [Abstract] [Full Text] [PDF]
	Efficacy and Safety of Ixabepilone (BMS-247550) in a Phase II Study of Patients With Advanced Breast Cancer Resistant to an Anthracycline, a Taxane, and Capecitabine
	Edith A. Perez, Guillermo Lerzo, Xavier Pivot, Eva Thomas, Linda Vahdat, Linda Bosserman, Patrice Viens, Can Cai, Brian Mullaney, Ronald Peck, and Gabriel N. Hortobagyi
	JCO Aug 10 2007: 3407–3414. First published on Jul 2 2007; 10.1200/JCO.2006.09.3849. [Abstract] [Full Text] [PDF]
	Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, As First-Line Therapy in Patients With Metastatic Breast Cancer Previously Treated With Anthracycline Chemotherapy
	Henri Roché, Louise Yelle, Francesco Cognetti, Louis Mauriac, Craig Bunnell, Joseph Sparano, Pierre Kerbrat, Jean-Pierre Delord, Linda Vahdat, Ronald Peck, David Lebwohl, Rana Ezzeddine, and Hervé Curé
	JCO Aug 10 2007: 3415–3420. First published on Jul 2 2007; 10.1200/JCO.2006.09.7535. [Abstract] [Full Text] [PDF]
	Phase II Trial of Ixabepilone, an Epothilone B Analog, in Patients With Metastatic Breast Cancer Previously Untreated With Taxanes
	Neelima Denduluri, Jennifer A. Low, James J. Lee, Arlene W. Berman, Janice M. Walshe, Ujala Vatas, Catherine K. Chow, Seth M. Steinberg, Sherry X. Yang, and Sandra M. Swain
	JCO Aug 10 2007: 3421–3427. First published on Jul 2 2007; 10.1200/JCO.2006.10.0784. [Abstract] [Full Text] [PDF]
	Receipt of Appropriate Primary Breast Cancer Therapy and Adjuvant Therapy Are Not Associated With Obesity in Older Women With Access to Health Care
	Diana S.M. Buist, Laura Ichikawa, Marianne N. Prout, Marianne Ulcickas Yood, Terry S. Field, Cynthia Owusu, Ann M. Geiger, Virginia P. Quinn, Feifei Wei, and Rebecca A. Silliman
	JCO Aug 10 2007: 3428–3436. [Abstract] [Full Text] [PDF]
	Regional Changes in Hormone Therapy Use and Breast Cancer Incidence in California From 2001 to 2004
	Anthony S. Robbins and Christina A. Clarke
	JCO Aug 10 2007: 3437–3439. First published on Jun 25 2007; 10.1200/JCO.2007.11.4132. [Abstract] [Full Text] [PDF]
	Fusion of Metabolic Function and Morphology: Sequential [18F]Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Studies Yield New Insights Into the Natural History of Bone Metastases in Breast Cancer
	Yong Du, Ian Cullum, Tim M. Illidge, and Peter J. Ell
	JCO Aug 10 2007: 3440–3447. First published on Jun 25 2007; 10.1200/JCO.2007.11.2854. [Abstract] [Full Text] [PDF]

Thoracic Oncology
	Phase II Clinical Trial of the Epothilone B Analog, Ixabepilone, in Patients With Non–Small-Cell Lung Cancer Whose Tumors Have Failed First-Line Platinum-Based Chemotherapy
	Johan Vansteenkiste, Primo N. Lara, Jr, Thierry Le Chevalier, Jean-Luc Breton, Philip Bonomi, Alan B. Sandler, Mark A. Socinski, Catherine Delbaldo, Brent McHenry, David Lebwohl, Ronald Peck, and Mark Edelman
	JCO Aug 10 2007: 3448–3455. First published on Jul 2 2007; 10.1200/JCO.2006.09.7097. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Irinotecan Fluorouracil Plus Leucovorin Is Not Superior to Fluorouracil Plus Leucovorin Alone As Adjuvant Treatment for Stage III Colon Cancer: Results of CALGB 89803
	Leonard B. Saltz, Donna Niedzwiecki, Donna Hollis, Richard M. Goldberg, Alexander Hantel, James P. Thomas, Anthony L.A. Fields, and Robert J. Mayer
	JCO Aug 10 2007: 3456–3461. [Abstract] [Full Text] [PDF] [Chinese PDF]
	Statins and the Risk of Colorectal Cancer: A Meta-Analysis of 18 Studies Involving More Than 1.5 Million Patients
	Stefanos Bonovas, Kalitsa Filioussi, Christodoulos S. Flordellis, and Nikolaos M. Sitaras
	JCO Aug 10 2007: 3462–3468. [Abstract] [Full Text] [PDF]
	Impact of Complete Response to Chemotherapy on Overall Survival in Advanced Colorectal Cancer: Results From Intergroup N9741
	Grace K. Dy, James E. Krook, Erin M. Green, Daniel J. Sargent, Thierry Delaunoit, Roscoe F. Morton, Charles S. Fuchs, Ramesh K. Ramanathan, Stephen K. Williamson, Brian P. Findlay, Barbara A. Pockaj, Robert P. Sticca, Steven R. Alberts, Henry C. Pitot, IV, and Richard M. Goldberg
	JCO Aug 10 2007: 3469–3474. [Abstract] [Full Text] [PDF] [Chinese PDF] [Publisher's Note]

Supportive Care and Quality of Life
	Donepezil for Cancer Fatigue: A Double-Blind, Randomized, Placebo-Controlled Trial
	Eduardo Bruera, Badi El Osta, Vicente Valero, Larry C. Driver, Be-Lian Pei, Loren Shen, Valerie A. Poulter, and J. Lynn Palmer
	JCO Aug 10 2007: 3475–3481. [Abstract] [Full Text] [PDF]

Clinical Trials
	Statistical Power of Negative Randomized Controlled Trials Presented at American Society for Clinical Oncology Annual Meetings
	Philippe L. Bedard, Monika K. Krzyzanowska, Melania Pintilie, and Ian F. Tannock
	JCO Aug 10 2007: 3482–3487. [Abstract] [Full Text] [PDF] [Data Supplement]
	Attitudes Toward Research Participation and Investigator Conflicts of Interest Among Advanced Cancer Patients Participating in Early Phase Clinical Trials
	Stacy W. Gray, Fay J. Hlubocky, Mark J. Ratain, and Christopher K. Daugherty
	JCO Aug 10 2007: 3488–3494. [Abstract] [Full Text] [PDF] [Data Supplement]

Hematologic Malignancies
	Two Cycles of Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine Plus Extended-Field Radiotherapy Is Superior to Radiotherapy Alone in Early Favorable Hodgkin's Lymphoma: Final Results of the GHSG HD7 Trial
	Andreas Engert, Jeremy Franklin, Hans Theodor Eich, Corinne Brillant, Susanne Sehlen, Claudio Cartoni, Richard Herrmann, Michael Pfreundschuh, Markus Sieber, Hans Tesch, Astrid Franke, Peter Koch, Maike de Wit, Ursula Paulus, Dirk Hasenclever, Markus Loeffler, Rolf-Peter Müller, Hans Konrad Müller-Hermelink, Eckhart Dühmke, and Volker Diehl
	JCO Aug 10 2007: 3495–3502. First published on Jul 2 2007; 10.1200/JCO.2006.07.0482. [Abstract] [Full Text] [PDF] [Polish PDF] [Russian PDF]
	Time-Dependent Prognostic Scoring System for Predicting Survival and Leukemic Evolution in Myelodysplastic Syndromes
	Luca Malcovati, Ulrich Germing, Andrea Kuendgen, Matteo G. Della Porta, Cristiana Pascutto, Rosangela Invernizzi, Aristoteles Giagounidis, Barbara Hildebrandt, Paolo Bernasconi, Sabine Knipp, Corinna Strupp, Mario Lazzarino, Carlo Aul, and Mario Cazzola
	JCO Aug 10 2007: 3503–3510. [Abstract] [Full Text] [PDF]
	Fertility and Risk Factors for Elevated Infertility Concern in 10-Year Hematopoietic Cell Transplant Survivors and Case-Matched Controls
	Camille Hammond, Janet R. Abrams, and Karen L. Syrjala
	JCO Aug 10 2007: 3511–3517. First published on Jul 23 2007; 10.1200/JCO.2007.10.8993. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Scholastic Achievements of Childhood Leukemia Patients: A Nationwide, Register-Based Study
	Arja H. Harila-Saari, Päivi M. Lähteenmäki, Eero Pukkala, Pentti Kyyrönen, Marjatta Lanning, and Risto Sankila
	JCO Aug 10 2007: 3518–3524. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Trastuzumab-Related Cardiotoxicity: Calling Into Question the Concept of Reversibility
	Melinda L. Telli, Sharon A. Hunt, Robert W. Carlson, and Alice E. Guardino
	JCO Aug 10 2007: 3525–3533. [Abstract] [Full Text] [PDF]

SPECIAL ARTICLE
	Who Should Be Sent for Genetic Testing in Hereditary Colorectal Cancer Syndromes?
	Henry T. Lynch, C. Richard Boland, Miguel A. Rodriguez-Bigas, Christopher Amos, Jane F. Lynch, and Patrick M. Lynch
	JCO Aug 10 2007: 3534–3542. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Fatal Pulmonary Toxicity in Testis Cancer With Bleomycin-Containing Chemotherapy

Anita Keijzer and Bart Kuenen

JCO Aug 10 2007: 3543–3544. [Full Text] [PDF]

Tumor Lysis Syndrome After Treatment of a Gastrointestinal Stromal Tumor With the Oral Tyrosine Kinase Inhibitor Sunitinib

Philip J. Saylor and Tony R. Reid

JCO Aug 10 2007: 3544–3546. [Full Text] [PDF]

Intracardiac Metastasis of Germ Cell Tumor Complicated by Pulmonary Hypertension and Thrombocytopenia

Jerry X. Liu, Bogdan Eftimie, and Joanne Mortimer

JCO Aug 10 2007: 3547–3549. [Full Text] [PDF]

CORRESPONDENCE
	The Fallacy of Single-Agent Chemotherapy for Cancer
	Henry S. Friedman and Jill Maxwell
	JCO Aug 10 2007: 3550. [Full Text] [PDF]
	In Reply
	Roger Stupp and Monika E. Hegi
	JCO Aug 10 2007: 3550–3551. [Full Text] [PDF]
	More Than a Name
	Stephanie V. Blank and John P. Curtin
	JCO Aug 10 2007: 3551. [Full Text] [PDF]
	Chemotherapy Administration for Ovarian Cancer by Gynecologic Oncologists and Medical Oncologists
	Andrew Berchuck
	JCO Aug 10 2007: 3552. [Full Text] [PDF]
	Type of Oncology Specialist and Treatment-Related Outcomes in Ovarian Cancer
	Mark A. Hoffman and Uzma Iqbal
	JCO Aug 10 2007: 3553. [Full Text] [PDF]
	Does Ovarian Cancer Treatment and Survival Differ by the Specialty Providing Chemotherapy?
	Maurie Markman
	JCO Aug 10 2007: 3554. [Full Text] [PDF]
	Ovarian Cancer and the Battle of the Specialists
	William P. McGuire
	JCO Aug 10 2007: 3554–3555. [Full Text] [PDF]
	In Reply
	Jeffrey H. Silber and Paul R. Rosenbaum
	JCO Aug 10 2007: 3555–3557. [Full Text] [PDF]
	In Reply
	Stephen A. Cannistra
	JCO Aug 10 2007: 3557–3558. [Full Text] [PDF]
	Reversible Posterior Leukoencephalopathy Syndrome Induced by Sunitinib
	German Martín, Lorena Bellido, and Juan Jesus Cruz
	JCO Aug 10 2007: 3559. [Full Text] [PDF]
	Forkhead Box P3-Positive Regulatory T Cells As Therapeutic Target for Breast Cancer
	Gianluigi Ferretti
	JCO Aug 10 2007: e29. [Full Text] [PDF]
	In Reply
	Gaynor J. Bates and Alison H. Banham
	JCO Aug 10 2007: e30. [Full Text] [PDF]

ERRATUM

ERRATUM

JCO Aug 10 2007: 3561. [Full Text] [PDF]

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