EDITORIALS

Interpreting P Values in Pharmacogenetic Studies: A Call for Process and Perspective

Michael L. Maitland, Mark J. Ratain, and Nancy J. Cox

JCO Oct 10 2007: 4513–4515. [Full Text] [PDF]

Combined Antiangiogenesis and Antiepidermal Growth Factor Receptor Targeting in the Treatment of Cancer: Hold Back, We Are Not There Yet

José Baselga and Josep Tabernero

JCO Oct 10 2007: 4516–4518. First published on Sep 17 2007; 10.1200/JCO.2007.12.8900. [Full Text] [PDF]

Combining Epigenetic and Cytotoxic Therapy in the Treatment of Solid Tumors

Elizabeth R. Plimack, David J. Stewart, and Jean-Pierre J. Issa

JCO Oct 10 2007: 4519–4521. [Full Text] [PDF]

Where Adolescents and Young Adults With Cancer Receive Their Care: Does It Matter?

Brad H. Pollock

JCO Oct 10 2007: 4522–4523. [Full Text] [PDF]

Colorectal Liver Metastases: Treat Effectively Up Front and Consider the Borderline Resectable

Jean-Nicolas Vauthey

JCO Oct 10 2007: 4524–4525. [Full Text] [PDF]

Screening for Psychological Distress in Cancer Patients: Challenges and Opportunities

Paul B. Jacobsen

JCO Oct 10 2007: 4526–4527. First published on Sep 10 2007; 10.1200/JCO.2007.13.1367. [Full Text] [PDF]

ORIGINAL REPORTS
Gynecologic Cancer
	Pharmacogenetic Assessment of Toxicity and Outcome After Platinum Plus Taxane Chemotherapy in Ovarian Cancer: The Scottish Randomised Trial in Ovarian Cancer
	Sharon Marsh, Jim Paul, Cristi R. King, Gillian Gifford, Howard L. McLeod, and Robert Brown
	JCO Oct 10 2007: 4528–4535. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Randomized Phase II Study of Erlotinib Combined With Bevacizumab Compared With Bevacizumab Alone in Metastatic Renal Cell Cancer
	Ronald M. Bukowski, Fairooz F. Kabbinavar, Robert A. Figlin, Keith Flaherty, Sandy Srinivas, Ulka Vaishampayan, Harry A. Drabkin, Janice Dutcher, Sarah Ryba, Qi Xia, Frank A. Scappaticci, and David McDermott
	JCO Oct 10 2007: 4536–4541. First published on Sep 17 2007; 10.1200/JCO.2007.11.5154. [Abstract] [Full Text] [PDF]
	Tumor Necrosis Factor As a New Target for Renal Cell Carcinoma: Two Sequential Phase II Trials of Infliximab at Standard and High Dose
	Michelle L. Harrison, Eva Obermueller, Nick R. Maisey, Susan Hoare, Kim Edmonds, Ningfeng F. Li, David Chao, Kate Hall, Chooi Lee, Eleni Timotheadou, Kellie Charles, Roger Ahern, D. Mike King, Tim Eisen, Robert Corringham, Mark DeWitte, Frances Balkwill, and Martin Gore
	JCO Oct 10 2007: 4542–4549. [Abstract] [Full Text] [PDF]
	Human Papillomavirus-16 Is the Predominant Type Etiologically Involved in Penile Squamous Cell Carcinoma
	Daniëlle A.M. Heideman, Tim Waterboer, Michael Pawlita, Pien Delis-van Diemen, Ingo Nindl, Joost A. Leijte, Johannes M.G. Bonfrer, Simon Horenblas, Chris J.L.M. Meijer, and Peter J.F. Snijders
	JCO Oct 10 2007: 4550–4556. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Randomized Phase II Trial of Cetuximab, Bevacizumab, and Irinotecan Compared With Cetuximab and Bevacizumab Alone in Irinotecan-Refractory Colorectal Cancer: The BOND-2 Study
	Leonard B. Saltz, Heinz-Josef Lenz, Hedy L. Kindler, Howard S. Hochster, Scott Wadler, Paulo M. Hoff, Nancy E. Kemeny, Ellen M. Hollywood, Mithat Gonen, Marcus Quinones, Meroe Morse, and Helen X. Chen
	JCO Oct 10 2007: 4557–4561. First published on Sep 17 2007; 10.1200/JCO.2007.12.0949. [Abstract] [Full Text] [PDF] [Polish PDF] [Publisher's Note]
	Surrogate End Points for Median Overall Survival in Metastatic Colorectal Cancer: Literature-Based Analysis From 39 Randomized Controlled Trials of First-Line Chemotherapy
	Patricia A. Tang, Søren M. Bentzen, Eric X. Chen, and Lillian L. Siu
	JCO Oct 10 2007: 4562–4568. First published on Sep 17 2007; 10.1200/JCO.2006.08.1935. [Abstract] [Full Text] [PDF] [Chinese PDF]
	End Points for Colon Cancer Adjuvant Trials: Observations and Recommendations Based on Individual Patient Data From 20,898 Patients Enrolled Onto 18 Randomized Trials From the ACCENT Group
	Daniel J. Sargent, Smitha Patiyil, Greg Yothers, Daniel G. Haller, Richard Gray, Jacqueline Benedetti, Marc Buyse, Roberto Labianca, Jean Francois Seitz, Christopher J. O'Callaghan, Guido Francini, Axel Grothey, Michael O'Connell, Paul J. Catalano, David Kerr, Erin Green, Harry S. Wieand, Richard M. Goldberg, and Aimery de Gramont
	JCO Oct 10 2007: 4569–4574. First published on Sep 17 2007; 10.1200/JCO.2006.10.4323. [Abstract] [Full Text] [PDF]
	Actual 10-Year Survival After Resection of Colorectal Liver Metastases Defines Cure
	James S. Tomlinson, William R. Jarnagin, Ronald P. DeMatteo, Yuman Fong, Peter Kornprat, Mithat Gonen, Nancy Kemeny, Murray F. Brennan, Leslie H. Blumgart, and Michael D'Angelica
	JCO Oct 10 2007: 4575–4580. [Abstract] [Full Text] [PDF]
	Concurrent Chemotherapy and Intensity-Modulated Radiation Therapy for Anal Canal Cancer Patients: A Multicenter Experience
	Joseph K. Salama, Loren K. Mell, David A. Schomas, Robert C. Miller, Kiran Devisetty, Ashesh B. Jani, Arno J. Mundt, John C. Roeske, Stanley L. Liauw, and Steven J. Chmura
	JCO Oct 10 2007: 4581–4586. [Abstract] [Full Text] [PDF]
	Phase I Study of Oxaliplatin, Full-Dose Gemcitabine, and Concurrent Radiation Therapy in Pancreatic Cancer
	Sameer P. Desai, Edgar Ben-Josef, Daniel P. Normolle, Isaac R. Francis, Joel K. Greenson, Diane M. Simeone, Alfred E. Chang, Lisa M. Colletti, Theodore S. Lawrence, and Mark M. Zalupski
	JCO Oct 10 2007: 4587–4592. [Abstract] [Full Text] [PDF]
	Hepatic Resection After Rescue Cetuximab Treatment for Colorectal Liver Metastases Previously Refractory to Conventional Systemic Therapy
	René Adam, Thomas Aloia, Francis Lévi, Dennis A. Wicherts, Robbert J. de Haas, Bernard Paule, Marie-Pierre Bralet, Mohamed Bouchahda, David Machover, Michel Ducreux, Vincent Castagne, Daniel Azoulay, and Denis Castaing
	JCO Oct 10 2007: 4593–4602. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I and Pharmacodynamic Trial of the DNA Methyltransferase Inhibitor Decitabine and Carboplatin in Solid Tumors
	Kim Appleton, Helen J. Mackay, Ian Judson, Jane A. Plumb, Carol McCormick, Gordon Strathdee, Chooi Lee, Sophie Barrett, Sarah Reade, Dalal Jadayel, Adrian Tang, Katharine Bellenger, Lynsay Mackay, Albert Setanoians, Andreas Schätzlein, Chris Twelves, Stanley B. Kaye, and Robert Brown
	JCO Oct 10 2007: 4603–4609. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Access to Pediatric Cancer Care by Age, Race, and Diagnosis, and Outcomes of Cancer Treatment in Pediatric and Adolescent Patients in the State of Georgia
	Della L. Howell, Kevin C. Ward, Harland D. Austin, John L. Young, and William G. Woods
	JCO Oct 10 2007: 4610–4615. [Abstract] [Full Text] [PDF]
	Site of Oncologic Specialty Care for Older Adolescents in Utah
	Karen H. Albritton, Charles H. Wiggins, Harold E. Nelson, and Jane C. Weeks
	JCO Oct 10 2007: 4616–4621. [Abstract] [Full Text] [PDF]
	Phase II Trial of Irinotecan in Children With Refractory Solid Tumors: A Children's Oncology Group Study
	Lisa R. Bomgaars, Mark Bernstein, Mark Krailo, Richard Kadota, Soma Das, Zhengjia Chen, Peter C. Adamson, and Susan M. Blaney
	JCO Oct 10 2007: 4622–4627. [Abstract] [Full Text] [PDF]

Breast Cancer
	Women's Interest in Gene Expression Analysis for Breast Cancer Recurrence Risk
	Suzanne C. O'Neill, Noel T. Brewer, Sarah E. Lillie, Edward F. Morrill, E. Claire Dees, Lisa A. Carey, and Barbara K. Rimer
	JCO Oct 10 2007: 4628–4634. [Abstract] [Full Text] [PDF] [Data Supplement]
	BRCA1 and BRCA2 Genetic Testing in Hispanic Patients: Mutation Prevalence and Evaluation of the BRCAPRO Risk Assessment Model
	Kristen J. Vogel, Deann P. Atchley, Julie Erlichman, Kristine R. Broglio, Kaylene J. Ready, Vicente Valero, Christopher I. Amos, Gabriel N. Hortobagyi, Karen H. Lu, and Banu Arun
	JCO Oct 10 2007: 4635–4641. [Abstract] [Full Text] [PDF]

Ethics
	Disclosure of Conflicts of Interest by Authors of Clinical Trials and Editorials in Oncology
	Rachel P. Riechelmann, Lisa Wang, Aoife O'Carroll, and Monika K. Krzyzanowska
	JCO Oct 10 2007: 4642–4647. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Assessment of Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma by Absolute Lymphocyte Counts in 2,126 Patients: 20 Years of Experience at The University of Texas M.D. Anderson Cancer Center
	Apostolia M. Tsimberidou, Sijin Wen, Susan O'Brien, Peter McLaughlin, William G. Wierda, Alessandra Ferrajoli, Stefan Faderl, John Manning, Susan Lerner, Chinh V. Mai, Alma M. Rodriguez, Mark Hess, Kim-Anh Do, Emil J. Freireich, Hagop M. Kantarjian, L. Jeffrey Medeiros, and Michael J. Keating
	JCO Oct 10 2007: 4648–4656. [Abstract] [Full Text] [PDF] [Chinese PDF]

Supportive Care and Quality of Life
	Self-Administered Stress Management Training in Patients Undergoing Radiotherapy
	Mindy M. Krischer, Ping Xu, Cathy D. Meade, and Paul B. Jacobsen
	JCO Oct 10 2007: 4657–4662. First published on Sep 17 2007; 10.1200/JCO.2006.09.0126. [Abstract] [Full Text] [PDF]

Thoracic Oncology
	Cisplatin Plus Gemcitabine or Vinorelbine for Elderly Patients With Advanced Non–Small-Cell Lung Cancer: The MILES-2P Studies
	Cesare Gridelli, Paolo Maione, Alfonso Illiano, Franco Vito Piantedosi, Adolfo Favaretto, Alessandra Bearz, Sergio Federico Robbiati, Virginio Filipazzi, Vito Lorusso, Francesco Carrozza, Rosario Vincenzo Iaffaioli, Luigi Manzione, Ciro Gallo, Alessandro Morabito, and Francesco Perrone
	JCO Oct 10 2007: 4663–4669. [Abstract] [Full Text] [PDF]

SPECIAL ARTICLE
	Pooled Results From 38 Analyses of the Accuracy of Distress Thermometer and Other Ultra-Short Methods of Detecting Cancer-Related Mood Disorders
	Alex J. Mitchell
	JCO Oct 10 2007: 4670–4681. First published on Sep 10 2007; 10.1200/JCO.2006.10.0438. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Chronic Myeloid Leukemia and Gastrointestinal Stromal Tumor: Simultaneous Presentation

Russell Gollard, William Wierda, and Jonathan Trent

JCO Oct 10 2007: 4682–4683. [Full Text] [PDF]

Perineural CNS Invasion in Primary Cutaneous Follicular Center Lymphoma

Edwarda M. Buda-Okreglak, Michael J. Walden, and Mark D. Brissette

JCO Oct 10 2007: 4684–4686. [Full Text] [PDF]

Bilateral Germ Cell Tumors and Androgen Insensitivity Syndrome

Homayoon Shahidi and Mark Robia

JCO Oct 10 2007: 4686–4688. [Full Text] [PDF]

CORRESPONDENCE

Dexrazoxane-Associated Risk for Secondary Malignancies in Pediatric Hodgkin's Disease: A Claim Without Evidence

Kurt Hellmann

JCO Oct 10 2007: 4689–4690. [Full Text] [PDF]

In Reply

Cindy L. Schwartz, Louis S. Constine, Wendy B. London, Richard Sposto, Debra L. Friedman, Cameron K. Tebbi, Nancy Mendenhall, Allen R. Chen, Pedro A. de Alarcon, Doojduen Villaluna, and Allen R. Chauvenet

JCO Oct 10 2007: 4690–4691. [Full Text] [PDF]

Targeted Therapies: Cui Prodest?

Daris Ferrari and Paolo Foa

JCO Oct 10 2007: 4691–4692. [Full Text] [PDF]

In Reply

Paulo M. Hoff and Lee M. Ellis

JCO Oct 10 2007: 4692. [Full Text] [PDF]

Does Adjuvant Vaccine Therapy Really Have Activity in Malignant Melanoma?

Keith Wheatley, Natalie J. Ives, and Paul Lorigan

JCO Oct 10 2007: 4693. [Full Text] [PDF]

In Reply

Malcolm S. Mitchell

JCO Oct 10 2007: 4693–4695. [Full Text] [PDF]

Transforming Growth Factor-ß Signaling and Regulatory T Cells

Gianluigi Ferretti, Alessandra Felici, Francesco Cognetti, and Mario Mandala

JCO Oct 10 2007: 4695–4696. [Full Text] [PDF]

In Reply

Paola Filipazzi, Chiara Castelli, Valenti Roberta, Veronica Huber, Manuela Iero, Lorenzo Pilla, Licia Rivoltini, and Giorgio Parmiani

JCO Oct 10 2007: 4696–4697. [Full Text] [PDF]

Radiation-Induced Prevention of Erlotinib-Induced Skin Rash Is Transient: A New Aspect Toward the Understanding of Epidermal Growth Factor Receptor Inhibitor–Associated Cutaneous Adverse Effects

Peter Arne Gerber, Elaine Enderlein, Bernhard Homey, Anja Muller, Edwin Boelke, and Wilfried Budach

JCO Oct 10 2007: 4697–4698. [Full Text] [PDF]

In Reply

Sankha S. Mitra

JCO Oct 10 2007: 4698–4699. [Full Text] [PDF]

Using Prospect Theory to Understand End-of-Life Decisions

Jeffrey D. Clough

JCO Oct 10 2007: 4700. [Full Text] [PDF]

ERRATUM

ERRATUM

JCO Oct 10 2007: 4701. [Full Text] [PDF]

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