Other Issues:		[Index by Author]
Contents:	Volume 27, Issue 26 September 10, 2009

	EDITORIALS
	COMMENTS AND CONTROVERSIES
	ORIGINAL REPORTS
	Epidemiology
	Thoracic Oncology
	Radiation Oncology
	Breast Cancer
	Diagnostics
	Genitourinary Cancer
	Gastrointestinal Cancer
	Palliative and Supportive Care
	Hematologic Malignancies
	Pediatric Oncology
	Health Services and Outcomes
	Phase I and Clinical Pharmacology
	REVIEW ARTICLE
	SPECIAL ARTICLE
	DIAGNOSIS IN ONCOLOGY
	CORRESPONDENCE

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                                      EDITORIALS

Secondary Breast Cancer in Hodgkin's Lymphoma Survivors Michael Crump and David Hodgson JCO Sep 2009: 4229–4231. First published on Aug 10 2009; 10.1200/JCO.2009.22.9120. [Full Text] [PDF]

EML4-ALK: Honing In on a New Target in Non–Small-Cell Lung Cancer Leora Horn and William Pao JCO Sep 2009: 4232–4235. First published on Aug 10 2009; 10.1200/JCO.2009.23.6661. [Full Text] [PDF]

                                      COMMENTS AND CONTROVERSIES

Therapeutic Effect of Sentinel Lymph Node Biopsy in Melanoma Remains an Open Question Phyllis A. Gimotty, Frank Yoon, Rachel Hammond, Paul Rosenbaum, and DuPont Guerry JCO Sep 2009: 4236–4238. First published on Aug 10 2009; 10.1200/JCO.2009.23.4518. [Full Text] [PDF]

                                      ORIGINAL REPORTS
Epidemiology

Breast Cancer Risk in Female Survivors of Hodgkin's Lymphoma: Lower Risk After Smaller Radiation Volumes Marie L. De Bruin, Judith Sparidans, Mars B. van't Veer, Evert M. Noordijk, Marieke W.J. Louwman, Josée M. Zijlstra, Hendrik van den Berg, Nicola S. Russell, Annegien Broeks, Margreet H.A. Baaijens, Berthe M.P. Aleman, and Flora E. van Leeuwen JCO Sep 2009: 4239–4246. First published on Aug 10 2009; 10.1200/JCO.2008.19.9174. [Abstract] [Full Text] [PDF]

Thoracic Oncology

Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK Alice T. Shaw, Beow Y. Yeap, Mari Mino-Kenudson, Subba R. Digumarthy, Daniel B. Costa, Rebecca S. Heist, Benjamin Solomon, Hannah Stubbs, Sonal Admane, Ultan McDermott, Jeffrey Settleman, Susumu Kobayashi, Eugene J. Mark, Scott J. Rodig, Lucian R. Chirieac, Eunice L. Kwak, Thomas J. Lynch, and A. John Iafrate JCO Sep 2009: 4247–4253. First published on Aug 10 2009; 10.1200/JCO.2009.22.6993. [Abstract] [Full Text] [PDF]

Different Impact of Excision Repair Cross-Complementation Group 1 on Survival in Male and Female Patients With Inoperable Non–Small-Cell Lung Cancer Treated With Carboplatin and Gemcitabine Bente Holm, Anders Mellemgaard, Torsten Skov, and Birgit Guldhammer Skov JCO Sep 2009: 4254–4259. First published on Aug 10 2009; 10.1200/JCO.2008.18.8631. [Abstract] [Full Text] [PDF]

SOX Antibodies in Small-Cell Lung Cancer and Lambert-Eaton Myasthenic Syndrome: Frequency and Relation With Survival Maarten J. Titulaer, Rinse Klooster, Marko Potman, Lidia Sabater, Francesc Graus, Ingrid M. Hegeman, Peter E. Thijssen, Paul W. Wirtz, Albert Twijnstra, Peter A.E. Sillevis Smitt, Silvère M. van der Maarel, and Jan J.G.M. Verschuuren JCO Sep 2009: 4260–4267. First published on Aug 10 2009; 10.1200/JCO.2008.20.6169. [Abstract] [Full Text] [PDF]

Quality-Adjusted Time Without Symptoms or Toxicity Analysis of Adjuvant Chemotherapy in Non–Small-Cell Lung Cancer: An Analysis of the National Cancer Institute of Canada Clinical Trials Group JBR.10 Trial Raymond W. Jang, Aurélie Le Maître, Keyue Ding, Tim Winton, Andrea Bezjak, Lesley Seymour, Frances A. Shepherd, and Natasha B. Leighl JCO Sep 2009: 4268–4273. First published on Aug 10 2009; 10.1200/JCO.2008.20.5815. [Abstract] [Full Text] [PDF]

Phase II, Multicenter, Uncontrolled Trial of Single-Agent Sorafenib in Patients With Relapsed or Refractory, Advanced Non–Small-Cell Lung Cancer George R. Blumenschein, Jr, Ulrich Gatzemeier, Frank Fossella, David J. Stewart, Lisa Cupit, Frank Cihon, James O'Leary, and Martin Reck JCO Sep 2009: 4274–4280. First published on Aug 3 2009; 10.1200/JCO.2009.22.0541. [Abstract] [Full Text] [PDF]

Radiation Oncology

Validation of Lysyl Oxidase As a Prognostic Marker for Metastasis and Survival in Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Trial 90-03 Quynh-Thu Le, Jonathan Harris, Anthony M. Magliocco, Christina S. Kong, Roman Diaz, Brian Shin, Hongbin Cao, Andy Trotti, Janine T. Erler, Christine H. Chung, Adam Dicker, Thomas F. Pajak, Amato J. Giaccia, and K. Kian Ang JCO Sep 2009: 4281–4286. First published on Aug 10 2009; 10.1200/JCO.2008.20.6003. [Abstract] [Full Text] [PDF] [Publisher's Note]

Breast Cancer

Evaluation of Microtubule-Associated Protein-Tau Expression As a Prognostic and Predictive Marker in the NSABP-B 28 Randomized Clinical Trial Lajos Pusztai, Jong-Hyeon Jeong, Yun Gong, Jeffrey S. Ross, Chungyeul Kim, Soonmyung Paik, Roman Rouzier, Fabrice Andre, Gabriel N. Hortobagyi, Norman Wolmark, and W. Fraser Symmans JCO Sep 2009: 4287–4292. First published on Aug 10 2009; 10.1200/JCO.2008.21.6887. [Abstract] [Full Text] [PDF]

Diagnostics

Chromogranin-A and N-Terminal Pro-Brain Natriuretic Peptide: An Excellent Pair of Biomarkers for Diagnostics in Patients With Neuroendocrine Tumor Catharina M. Korse, Babs G. Taal, Cornelis A. de Groot, Robert H. Bakker, and Johannes M.G. Bonfrer JCO Sep 2009: 4293–4299. First published on Aug 10 2009; 10.1200/JCO.2008.18.7047. [Abstract] [Full Text] [PDF]

Genitourinary Cancer

Prostate Cancer–Specific Mortality After Radical Prostatectomy for Patients Treated in the Prostate-Specific Antigen Era Andrew J. Stephenson, Michael W. Kattan, James A. Eastham, Fernando J. Bianco, Jr, Ofer Yossepowitch, Andrew J. Vickers, Eric A. Klein, David P. Wood, and Peter T. Scardino JCO Sep 2009: 4300–4305. First published on Jul 27 2009; 10.1200/JCO.2008.18.2501. [Abstract] [Full Text] [PDF]

Risk Assessment Among Prostate Cancer Patients Receiving Primary Androgen Deprivation Therapy Matthew R. Cooperberg, Shiro Hinotsu, Mikio Namiki, Kazuto Ito, Jeanette Broering, Peter R. Carroll, and Hideyuki Akaza JCO Sep 2009: 4306–4313. First published on Aug 10 2009; 10.1200/JCO.2008.21.5228. [Abstract] [Full Text] [PDF]

Prospective Study of [18F]Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for Staging of Muscle-Invasive Bladder Carcinoma Adam S. Kibel, Farrokh Dehdashti, Matthew D. Katz, Aleksandra P. Klim, Robert L. Grubb, Peter A. Humphrey, Cary Siegel, Dengfeng Cao, Feng Gao, and Barry A. Siegel JCO Sep 2009: 4314–4320. First published on Aug 3 2009; 10.1200/JCO.2008.20.6722. [Abstract] [Full Text] [PDF]

Three-Dimensional Prostate Mapping Biopsy Has a Potentially Significant Impact on Prostate Cancer Management Gary Onik, Matthew Miessau, and David G. Bostwick JCO Sep 2009: 4321–4326. First published on Aug 3 2009; 10.1200/JCO.2008.20.3497. [Abstract] [Full Text] [PDF]

Quality of Surveillance for Stage I Testis Cancer in the Community Hua-yin Yu, Rodger A. Madison, Claude M. Setodji, and Christopher S. Saigal JCO Sep 2009: 4327–4332. First published on Aug 3 2009; 10.1200/JCO.2008.19.9406. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer

Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Recombinant Human Intestinal Trefoil Factor Oral Spray for Prevention of Oral Mucositis in Patients With Colorectal Cancer Who Are Receiving Fluorouracil-Based Chemotherapy Douglas E. Peterson, Nicholas P. Barker, Lilia I. Akhmadullina, Irina Rodionova, Nailya Z. Sherman, Irina S. Davidenko, Galina N. Rakovskaya, Eugeny A. Gotovkin, Sergey A. Shinkarev, Mikhail V. Kopp, Eugeny P. Kulikov, Vladimir M. Moiseyenko, Joseph M. Gertner, Igor Firsov, Tamara Tuleneva, Alexander Yarosh, and Chee-Wai Woon JCO Sep 2009: 4333–4338. First published on Jul 27 2009; 10.1200/JCO.2008.21.2381. [Abstract] [Full Text] [PDF]

Predictive Capacity of Three Comorbidity Indices in Estimating Mortality After Surgery for Colon Cancer Robert B. Hines, Chakrapani Chatla, Harvey L. Bumpers, John W. Waterbor, Gerald McGwin, Jr, Ellen Funkhouser, Christopher S. Coffey, James Posey, and Upender Manne JCO Sep 2009: 4339–4345. First published on Aug 3 2009; 10.1200/JCO.2009.22.4758. [Abstract] [Full Text] [PDF]

Palliative and Supportive Care

Distress in Older Patients With Cancer Arti Hurria, Daneng Li, Kurt Hansen, Sujata Patil, Ravi Gupta, Christian Nelson, Stuart M. Lichtman, William P. Tew, Paul Hamlin, Enid Zuckerman, Jonathan Gardes, Sewanti Limaye, Mark Lachs, and Eva Kelly JCO Sep 2009: 4346–4351. First published on Aug 3 2009; 10.1200/JCO.2008.19.9463. [Abstract] [Full Text] [PDF]

Hematologic Malignancies

Prognostic Implications of NOTCH1 and FBXW7 Mutations in Adults With T-Cell Acute Lymphoblastic Leukemia Treated on the MRC UKALLXII/ECOG E2993 Protocol Marc R. Mansour, Maria L. Sulis, Veronique Duke, Letizia Foroni, Sarah Jenkinson, Kenneth Koo, Christopher G. Allen, Rosemary E. Gale, Georgina Buck, Sue Richards, Elisabeth Paietta, Jacob M. Rowe, Martin S. Tallman, Anthony H. Goldstone, Adolfo A. Ferrando, and David C. Linch JCO Sep 2009: 4352–4356. First published on Jul 27 2009; 10.1200/JCO.2009.22.0996. [Abstract] [Full Text] [PDF]

Phase II-I-II Study of Two Different Doses and Schedules of Pralatrexate, a High-Affinity Substrate for the Reduced Folate Carrier, in Patients With Relapsed or Refractory Lymphoma Reveals Marked Activity in T-Cell Malignancies Owen A. O'Connor, Steven Horwitz, Paul Hamlin, Carol Portlock, Craig H. Moskowitz, Debra Sarasohn, Ellen Neylon, Jill Mastrella, Rachel Hamelers, Barbara MacGregor-Cortelli, Molly Patterson, Venkatraman E. Seshan, Frank Sirotnak, Martin Fleisher, Diane R. Mould, Mike Saunders, and Andrew D. Zelenetz JCO Sep 2009: 4357–4364. First published on Aug 3 2009; 10.1200/JCO.2008.20.8470. [Abstract] [Full Text] [PDF]

Pre-Emptive Treatment With Rituximab of Molecular Relapse After Autologous Stem Cell Transplantation in Mantle Cell Lymphoma Niels S. Andersen, Lone B. Pedersen, Anna Laurell, Erkki Elonen, Arne Kolstad, Anne Marie Boesen, Lars M. Pedersen, Grete F. Lauritzsen, Roald Ekanger, Herman Nilsson-Ehle, Marie Nordström, Susanne Fredén, Mats Jerkeman, Mikael Eriksson, Jaan Väärt, Beatrice Malmer, and Christian H. Geisler JCO Sep 2009: 4365–4370. First published on Aug 3 2009; 10.1200/JCO.2008.21.3116. [Abstract] [Full Text] [PDF]

Phase I Study of the Humanized Anti-CD40 Monoclonal Antibody Dacetuzumab in Refractory or Recurrent Non-Hodgkin's Lymphoma Ranjana Advani, Andres Forero-Torres, Richard R. Furman, Joseph D. Rosenblatt, Anas Younes, Hong Ren, Kate Harrop, Nancy Whiting, and Jonathan G. Drachman JCO Sep 2009: 4371–4377. First published on Jul 27 2009; 10.1200/JCO.2008.21.3017. [Abstract] [Full Text] [PDF]

Phase III Randomized Study of Bendamustine Compared With Chlorambucil in Previously Untreated Patients With Chronic Lymphocytic Leukemia Wolfgang U. Knauf, Toshko Lissichkov, Ali Aldaoud, Anna Liberati, Javier Loscertales, Raoul Herbrecht, Gunnar Juliusson, Gerhard Postner, Liana Gercheva, Stefan Goranov, Martin Becker, Hans-Joerg Fricke, Francoise Huguet, Ilaria Del Giudice, Peter Klein, Lothar Tremmel, Karlheinz Merkle, and Marco Montillo JCO Sep 2009: 4378–4384. First published on Aug 3 2009; 10.1200/JCO.2008.20.8389. [Abstract] [Full Text] [PDF] [Publisher's Note]

Pediatric Oncology

Early and Late Therapy Response Assessment With [18F]Fluorodeoxyglucose Positron Emission Tomography in Pediatric Hodgkin's Lymphoma: Analysis of a Prospective Multicenter Trial Christian Furth, Ingo G. Steffen, Holger Amthauer, Juri Ruf, Daniel Misch, Stefan Schönberger, Carsten Kobe, Timm Denecke, Brigitte Stöver, Hubertus Hautzel, Günter Henze, and Patrick Hundsdoerfer JCO Sep 2009: 4385–4391. First published on Aug 10 2009; 10.1200/JCO.2008.19.7814. [Abstract] [Full Text] [PDF]

Phase II Study of Clofarabine in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia Sima Jeha, Bassem Razzouk, Michael Rytting, Susan Rheingold, Edythe Albano, Richard Kadota, Lori Luchtman-Jones, Lisa Bomgaars, Paul Gaynon, Stewart Goldman, Kim Ritchey, Robert Arceci, Arnold Altman, Kimo Stine, Laurel Steinherz, and Peter Steinherz JCO Sep 2009: 4392–4397. First published on Aug 3 2009; 10.1200/JCO.2008.18.8706. [Abstract] [Full Text] [PDF]

Health Services and Outcomes

Accelerated Approval of Cancer Drugs: Improved Access to Therapeutic Breakthroughs or Early Release of Unsafe and Ineffective Drugs? Elizabeth A. Richey, E. Alison Lyons, Jonathan R. Nebeker, Veena Shankaran, June M. McKoy, Thanh Ha Luu, Narissa Nonzee, Steven Trifilio, Oliver Sartor, Al B. Benson, III, Kenneth R. Carson, Beatrice J. Edwards, Douglas Gilchrist-Scott, Timothy M. Kuzel, Dennis W. Raisch, Martin S. Tallman, Dennis P. West, Steven Hirschfeld, Antonio J. Grillo-Lopez, and Charles L. Bennett JCO Sep 2009: 4398–4405. First published on Jul 27 2009; 10.1200/JCO.2008.21.1961. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology

Pharmacogenetic Pathway Analysis for Determination of Sunitinib-Induced Toxicity Nielka P. van Erp, Karel Eechoute, Astrid A. van der Veldt, John B. Haanen, An K.L. Reyners, Ron H.J. Mathijssen, Epie Boven, Tahar van der Straaten, Renée F. Baak-Pablo, Judith A.M. Wessels, Henk-Jan Guchelaar, and Hans Gelderblom JCO Sep 2009: 4406–4412. First published on Aug 10 2009; 10.1200/JCO.2008.21.7679. [Abstract] [Full Text] [PDF]

Mapatumumab, an Antibody Targeting TRAIL-R1, in Combination With Paclitaxel and Carboplatin in Patients With Advanced Solid Malignancies: Results of a Phase I and Pharmacokinetic Study Stephen Leong, Roger B. Cohen, Daniel L. Gustafson, Corey J. Langer, D. Ross Camidge, Kristin Padavic, Lia Gore, Margaret Smith, Laura Q. Chow, Margaret von Mehren, Cindy O'Bryant, Sujatha Hariharan, Sami Diab, Norma Lynn Fox, Renée Miceli, and S. Gail Eckhardt JCO Sep 2009: 4413–4421. First published on Aug 3 2009; 10.1200/JCO.2008.21.7422. [Abstract] [Full Text] [PDF]

                                      REVIEW ARTICLE

Targeting Signal Transducer and Activator of Transcription Signaling Pathway in Leukemias Mustafa Benekli, Heinz Baumann, and Meir Wetzler JCO Sep 2009: 4422–4432. First published on Aug 10 2009; 10.1200/JCO.2008.21.3264. [Abstract] [Full Text] [PDF]

                                      SPECIAL ARTICLE

Project Zero Delay: A Process for Accelerating the Activation of Cancer Clinical Trials Razelle Kurzrock, Susan Pilat, Marcel Bartolazzi, Dwana Sanders, Jill Van Wart Hood, Stanley D. Tucker, Kevin Webster, Michael A. Mallamaci, Steven Strand, Eileen Babcock, and Robert C. Bast, Jr JCO Sep 2009: 4433–4440. First published on Aug 3 2009; 10.1200/JCO.2008.21.6093. [Abstract] [Full Text] [PDF]

                                      DIAGNOSIS IN ONCOLOGY

Hodgkin's Lymphoma With Digital Clubbing Matthew J. Goodyer, Marie-Claire Cronin, Dawn G. Ketsitlile, Seamus P. O'Reilly, Eugene J. Moylan, Michael M. Maher, and John M. Hogan JCO Sep 2009: e95–e96. First published on Jun 29 2009; 10.1200/JCO.2008.21.7323. [Full Text] [PDF]

Response to a Novel Multitargeted Tyrosine Kinase Inhibitor Pazopanib in Metastatic Merkel Cell Carcinoma Matthew Davids, Amanda Charlton, Swee-Siang Ng, Mei-Ling Chong, Kevin Laubscher, Mohammed Dar, Jeffrey Hodge, Richie Soong, and Boon Cher Goh JCO Sep 2009: e97–e100. First published on Jun 29 2009; 10.1200/JCO.2009.21.8149. [Full Text] [PDF]

                                      CORRESPONDENCE

High Rate of Febrile Neutropenia in Patients With Operable Breast Cancer Receiving Docetaxel and Cyclophosphamide Derrick Soong, Reem Haj, Mova G. Leung, Robert Myers, Brian Higgins, Jeff Myers, and Sudha Rajagopal JCO Sep 2009: e101–e102. First published on Aug 3 2009; 10.1200/JCO.2009.23.0508. [Full Text] [PDF]

Breast Cancer Patients Unknowingly Dosing Themselves With Estrogen by Using Topical Moisturizers Adrienne C. Olson, John S. Link, James R. Waisman, and Thomas C. Kupiec JCO Sep 2009: e103–e104. First published on Aug 3 2009; 10.1200/JCO.2009.23.1225. [Full Text] [PDF]

"Sufficient Life Expectancy": An Amazing Inclusion Criterion in Cancer Phase II-III Trials Nicolas Penel, Stéphanie Clisant, Jean-Louis Lefebvre, and Antoine Adenis JCO Sep 2009: e105. First published on Aug 10 2009; 10.1200/JCO.2009.24.1810. [Full Text] [PDF]

Long-Term Response in Primary Renal Cancer to Sequential Antiangiogenic Therapy Nicholas J. Vogelzang, Wolfram Samlowski, and Alan Weissman JCO Sep 2009: e106–e107. First published on Aug 10 2009; 10.1200/JCO.2009.23.4021. [Full Text] [PDF]

2009 Version of the Chompret Criteria for Li Fraumeni Syndrome Julie Tinat, Gaelle Bougeard, Stéphanie Baert-Desurmont, Stéphanie Vasseur, Cosette Martin, Emilie Bouvignies, Olivier Caron, Brigitte Bressac-de Paillerets, Pascaline Berthet, Catherine Dugast, Catherine Bonaïti-Pellié, Dominique Stoppa-Lyonnet, and Thierry Frébourg JCO Sep 2009: e108–e109. First published on Aug 3 2009; 10.1200/JCO.2009.22.7967. [Full Text] [PDF]

Reply to J. Tinat et al Kelly D.F. Gonzalez, Carolyn H. Buzin, Jeffrey N. Weitzel, and Steve S. Sommer JCO Sep 2009: e110. First published on Aug 3 2009; 10.1200/JCO.2009.22.8353. [Full Text] [PDF]

Breast Cancer Subtypes and Response to Docetaxel in Node-Positive Breast Cancer: Use of an Immunohistochemical Definition in the BCIRG 001 Trial Lawrence C. Panasci JCO Sep 2009: e111. First published on Aug 10 2009; 10.1200/JCO.2009.23.8022. [Full Text] [PDF]

Reply to L.C. Panasci Judith Hugh, John Hanson, Maggie Cheang, Torsten Nielsen, Charles Perou, Charles Dumontet, John Reed, Maryla Krajewska, Isabelle Treilleux, Matthieu Rupin, Emmanuelle Magherini, John Mackey, Miguel Martin, and Charles Vogel JCO Sep 2009: e112–e113. First published on Aug 10 2009; 10.1200/JCO.2009.23.8691. [Full Text] [PDF]

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.