Other Issues:		[Index by Author]
Contents:	Volume 27, Issue 31 November 1, 2009

	EDITORIALS
	ORIGINAL REPORTS
	Gastrointestinal Cancer
	Breast Cancer
	Pediatric Oncology
	Hematologic Malignancies
	Cancer-Related Complications
	Genitourinary Cancer
	Thoracic Oncology
	Phase I and Clinical Pharmacology
	REVIEW ARTICLE
	BIOLOGY OF NEOPLASIA
	ART OF ONCOLOGY
	DIAGNOSIS IN ONCOLOGY
	CORRESPONDENCE

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                                      EDITORIALS

Is Preoperative Chemoradiotherapy Still the Treatment of Choice for Rectal Cancer? Bruce D. Minsky JCO Nov 2009: 5115–5116. First published on Sep 21 2009; 10.1200/JCO.2009.22.9112. [Full Text] [PDF]

Combined Hormone Therapy at Menopause and Breast Cancer: A Warning—Short-Term Use Increases Risk Leslie Bernstein JCO Nov 2009: 5116–5119. First published on Sep 14 2009; 10.1200/JCO.2009.23.9988. [Full Text] [PDF]

Exploring the Impact of the Hormonal Milieu on Cognitive Functioning Steven A. Castellon and Patricia A. Ganz JCO Nov 2009: 5119–5121. First published on Sep 21 2009; 10.1200/JCO.2009.24.3329. [Full Text] [PDF]

Toward a Total Cure for Acute Lymphoblastic Leukemia Ching-Hon Pui JCO Nov 2009: 5121–5123. First published on Oct 5 2009; 10.1200/JCO.2009.24.8518. [Full Text] [PDF]

                                      ORIGINAL REPORTS
Gastrointestinal Cancer

Preoperative Multimodality Therapy Improves Disease-Free Survival in Patients With Carcinoma of the Rectum: NSABP R-03 Mark S. Roh, Linda H. Colangelo, Michael J. O'Connell, Greg Yothers, Melvin Deutsch, Carmen J. Allegra, Morton S. Kahlenberg, Luis Baez-Diaz, Carol S. Ursiny, Nicholas J. Petrelli, and Norman Wolmark JCO Nov 2009: 5124–5130. First published on Sep 21 2009; 10.1200/JCO.2009.22.0467. [Abstract] [Full Text] [PDF]

Perineural Invasion Is an Independent Predictor of Outcome in Colorectal Cancer Catherine Liebig, Gustavo Ayala, Jonathan Wilks, Gordana Verstovsek, Hao Liu, Neeti Agarwal, David H. Berger, and Daniel Albo JCO Nov 2009: 5131–5137. First published on Sep 8 2009; 10.1200/JCO.2009.22.4949. [Abstract] [Full Text] [PDF]

Breast Cancer

Estrogen-Progestagen Menopausal Hormone Therapy and Breast Cancer: Does Delay From Menopause Onset to Treatment Initiation Influence Risks? Agnès Fournier, Sylvie Mesrine, Marie-Christine Boutron-Ruault, and Françoise Clavel-Chapelon JCO Nov 2009: 5138–5143. First published on Sep 14 2009; 10.1200/JCO.2008.21.6432. [Abstract] [Full Text] [PDF]

Effects of Tamoxifen and Raloxifene on Memory and Other Cognitive Abilities: Cognition in the Study of Tamoxifen and Raloxifene Claudine Legault, Pauline M. Maki, Susan M. Resnick, Laura Coker, Patricia Hogan, Therese B. Bevers, and Sally A. Shumaker JCO Nov 2009: 5144–5152. First published on Sep 21 2009; 10.1200/JCO.2008.21.0716. [Abstract] [Full Text] [PDF]

Circulating Tumor Cells: A Useful Predictor of Treatment Efficacy in Metastatic Breast Cancer Minetta C. Liu, Peter G. Shields, Robert D. Warren, Philip Cohen, Mary Wilkinson, Yvonne L. Ottaviano, Suman B. Rao, Jennifer Eng-Wong, Francoise Seillier-Moiseiwitsch, Anne-Michelle Noone, and Claudine Isaacs JCO Nov 2009: 5153–5159. First published on Sep 14 2009; 10.1200/JCO.2008.20.6664. [Abstract] [Full Text] [PDF]

Underuse of Breast Cancer Adjuvant Treatment: Patient Knowledge, Beliefs, and Medical Mistrust Nina A. Bickell, Jessica Weidmann, Kezhen Fei, Jenny J. Lin, and Howard Leventhal JCO Nov 2009: 5160–5167. First published on Sep 21 2009; 10.1200/JCO.2009.22.9773. [Abstract] [Full Text] [PDF]

Pediatric Oncology

Risk of Relapse of Childhood Acute Lymphoblastic Leukemia Is Predicted By Flow Cytometric Measurement of Residual Disease on Day 15 Bone Marrow Giuseppe Basso, Marinella Veltroni, Maria Grazia Valsecchi, Michael N. Dworzak, Richard Ratei, Daniela Silvestri, Alessandra Benetello, Barbara Buldini, Oscar Maglia, Giuseppe Masera, Valentino Conter, Maurizio Arico, Andrea Biondi, and Giuseppe Gaipa JCO Nov 2009: 5168–5174. First published on Oct 5 2009; 10.1200/JCO.2008.20.8934. [Abstract] [Full Text] [PDF] [Publisher's Note]

Improved Early Event-Free Survival With Imatinib in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Children's Oncology Group Study Kirk R. Schultz, W. Paul Bowman, Alexander Aledo, William B. Slayton, Harland Sather, Meenakshi Devidas, Chenguang Wang, Stella M. Davies, Paul S. Gaynon, Michael Trigg, Robert Rutledge, Laura Burden, Dean Jorstad, Andrew Carroll, Nyla A. Heerema, Naomi Winick, Michael J. Borowitz, Stephen P. Hunger, William L. Carroll, and Bruce Camitta JCO Nov 2009: 5175–5181. First published on Oct 5 2009; 10.1200/JCO.2008.21.2514. [Abstract] [Full Text] [PDF]

Vincristine, Actinomycin, and Cyclophosphamide Compared With Vincristine, Actinomycin, and Cyclophosphamide Alternating With Vincristine, Topotecan, and Cyclophosphamide for Intermediate-Risk Rhabdomyosarcoma: Children's Oncology Group Study D9803 Carola A.S. Arndt, Julie A. Stoner, Douglas S. Hawkins, David A. Rodeberg, Andrea A. Hayes-Jordan, Charles N. Paidas, David M. Parham, Lisa A. Teot, Moody D. Wharam, John C. Breneman, Sarah S. Donaldson, James R. Anderson, and William H. Meyer JCO Nov 2009: 5182–5188. First published on Sep 21 2009; 10.1200/JCO.2009.22.3768. [Abstract] [Full Text] [PDF] [Publisher's Note]

Hematologic Malignancies

Young Adults With Acute Lymphoblastic Leukemia Have an Excellent Outcome With Chemotherapy Alone and Benefit From Intensive Postinduction Treatment: A Report From the Children's Oncology Group James B. Nachman, Mei K. La, Stephen P. Hunger, Nyla A. Heerema, Paul S. Gaynon, Caroline Hastings, Leonard A. Mattano, Jr, Harland Sather, Meenakshi Devidas, David R. Freyer, Peter G. Steinherz, and Nita L. Seibel JCO Nov 2009: 5189–5194. First published on Oct 5 2009; 10.1200/JCO.2008.20.8959. [Abstract] [Full Text] [PDF]

Real-Time Quantitative Polymerase Chain Reaction Detection of Minimal Residual Disease by Standardized WT1 Assay to Enhance Risk Stratification in Acute Myeloid Leukemia: A European LeukemiaNet Study Daniela Cilloni, Aline Renneville, Fabienne Hermitte, Robert K. Hills, Sarah Daly, Jelena V. Jovanovic, Enrico Gottardi, Milena Fava, Susanne Schnittger, Tamara Weiss, Barbara Izzo, Josep Nomdedeu, Adrian van der Heijden, Bert A. van der Reijden, Joop H. Jansen, Vincent H.J. van der Velden, Hans Ommen, Claude Preudhomme, Giuseppe Saglio, and David Grimwade JCO Nov 2009: 5195–5201. First published on Sep 14 2009; 10.1200/JCO.2009.22.4865. [Abstract] [Full Text] [PDF]

IKZF1 (Ikaros) Deletions in BCR-ABL1–Positive Acute Lymphoblastic Leukemia Are Associated With Short Disease-Free Survival and High Rate of Cumulative Incidence of Relapse: A GIMEMA AL WP Report Giovanni Martinelli, Ilaria Iacobucci, Clelia Tiziana Storlazzi, Marco Vignetti, Francesca Paoloni, Daniela Cilloni, Simona Soverini, Antonella Vitale, Sabina Chiaretti, Giuseppe Cimino, Cristina Papayannidis, Stefania Paolini, Loredana Elia, Paola Fazi, Giovanna Meloni, Sergio Amadori, Giuseppe Saglio, Fabrizio Pane, Michele Baccarani, and Robin Foà JCO Nov 2009: 5202–5207. First published on Sep 21 2009; 10.1200/JCO.2008.21.6408. [Abstract] [Full Text] [PDF]

5-Year Survival in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia in a Randomized, Phase III Trial of Fludarabine Plus Cyclophosphamide With or Without Oblimersen Susan O'Brien, Joseph O. Moore, Thomas E. Boyd, Loree M. Larratt, Aleksander B. Skotnicki, Benjamin Koziner, Asher A. Chanan-Khan, John F. Seymour, John Gribben, Loretta M. Itri, and Kanti R. Rai JCO Nov 2009: 5208–5212. First published on Sep 8 2009; 10.1200/JCO.2009.22.5748. [Abstract] [Full Text] [PDF]

Phase II Study of Yttrium-90–Ibritumomab Tiuxetan in Patients With Relapsed or Refractory Mantle Cell Lymphoma Michael Wang, Yasuhiro Oki, Barbara Pro, Jorge Enrique Romaguera, Maria Alma Rodriguez, Felipe Samaniego, Peter McLaughlin, Frederick Hagemeister, Sattva Neelapu, Amanda Copeland, Barry I. Samuels, Evelyne M. Loyer, Yuan Ji, and Anas Younes JCO Nov 2009: 5213–5218. First published on Sep 21 2009; 10.1200/JCO.2009.21.8545. [Abstract] [Full Text] [PDF]

New Lesions Detected by Single Nucleotide Polymorphism Array–Based Chromosomal Analysis Have Important Clinical Impact in Acute Myeloid Leukemia Ramon V. Tiu, Lukasz P. Gondek, Christine L. O'Keefe, Jungwon Huh, Mikkael A. Sekeres, Paul Elson, Michael A. McDevitt, Xiao Fei Wang, Mark J. Levis, Judith E. Karp, Anjali S. Advani, and Jaroslaw P. Maciejewski JCO Nov 2009: 5219–5226. First published on Sep 21 2009; 10.1200/JCO.2009.21.9840. [Abstract] [Full Text] [PDF] [Data Supplement] [Publisher's Note]

Primary Testicular Diffuse Large B-Cell Lymphoma: A Population-Based Study on the Incidence, Natural History, and Survival Comparison With Primary Nodal Counterpart Before and After the Introduction of Rituximab Jacob D. Gundrum, Michelle A. Mathiason, Derek B. Moore, and Ronald S. Go JCO Nov 2009: 5227–5232. First published on Sep 21 2009; 10.1200/JCO.2009.22.5896. [Abstract] [Full Text] [PDF]

Cancer-Related Complications

Prevalence, Natural Course, and Risk Factors of Insomnia Comorbid With Cancer Over a 2-Month Period Josée Savard, Julie Villa, Hans Ivers, Sébastien Simard, and Charles M. Morin JCO Nov 2009: 5233–5239. First published on Sep 8 2009; 10.1200/JCO.2008.21.6333. [Abstract] [Full Text] [PDF]

Genitourinary Cancer

Identification and Validation of a Gene Expression Signature That Predicts Outcome in Adult Men With Germ Cell Tumors James E. Korkola, Jane Houldsworth, Darren R. Feldman, Adam B. Olshen, Li-Xuan Qin, Sujata Patil, Victor E. Reuter, George J. Bosl, and R.S.K. Chaganti JCO Nov 2009: 5240–5247. First published on Sep 21 2009; 10.1200/JCO.2008.20.0386. [Abstract] [Full Text] [PDF] [Data Supplements]

Thoracic Oncology

Randomized Double-Blind Placebo-Controlled Trial of Thalidomide in Combination With Gemcitabine and Carboplatin in Advanced Non–Small-Cell Lung Cancer Siow Ming Lee, Robin Rudd, Penella J. Woll, Christian Ottensmeier, David Gilligan, Allan Price, Stephen Spiro, Nicole Gower, Mark Jitlal, and Allan Hackshaw JCO Nov 2009: 5248–5254. First published on Sep 21 2009; 10.1200/JCO.2009.21.9733. [Abstract] [Full Text] [PDF] [Data Supplements] [Publisher's Note]

Safety of Bevacizumab in Patients With Non–Small-Cell Lung Cancer and Brain Metastases Mark A. Socinski, Corey J. Langer, Jane E. Huang, Margaret M. Kolb, Peter Compton, Lisa Wang, and Wallace Akerley JCO Nov 2009: 5255–5261. First published on Sep 8 2009; 10.1200/JCO.2009.22.0616. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology

Phase I Study of the Safety, Tolerability, and Pharmacokinetics of Oral CP-868,596, a Highly Specific Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitor in Patients With Advanced Cancers Nancy L. Lewis, Lionel D. Lewis, Joseph P. Eder, Nandi J. Reddy, Feng Guo, Kristen J. Pierce, Anthony J. Olszanski, and Roger B. Cohen JCO Nov 2009: 5262–5269. First published on Sep 8 2009; 10.1200/JCO.2009.21.8487. [Abstract] [Full Text] [PDF] [Data Supplement]

Phase I Active Immunotherapy With Combination of Two Chimeric, Human Epidermal Growth Factor Receptor 2, B-Cell Epitopes Fused to a Promiscuous T-Cell Epitope in Patients With Metastatic and/or Recurrent Solid Tumors Pravin T.P. Kaumaya, Kevin Chu Foy, Joan Garrett, Sharad V. Rawale, Daniele Vicari, Jennifer M. Thurmond, Tammy Lamb, Aruna Mani, Yahaira Kane, Catherine R. Balint, Donald Chalupa, Gregory A. Otterson, Charles L. Shapiro, Jeffrey M. Fowler, Michael R. Grever, Tanios S. Bekaii-Saab, and William E. Carson, III JCO Nov 2009: 5270–5277. First published on Sep 14 2009; 10.1200/JCO.2009.22.3883. [Abstract] [Full Text] [PDF]

                                      REVIEW ARTICLE

Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Central Nervous System Metastases Brian Leyland-Jones JCO Nov 2009: 5278–5286. First published on Sep 21 2009; 10.1200/JCO.2008.19.8481. [Abstract] [Full Text] [PDF]

                                      BIOLOGY OF NEOPLASIA

Matrix Metalloproteinases As Novel Biomarkers and Potential Therapeutic Targets in Human Cancer Roopali Roy, Jiang Yang, and Marsha A. Moses JCO Nov 2009: 5287–5297. First published on Sep 8 2009; 10.1200/JCO.2009.23.5556. [Abstract] [Full Text] [PDF]

                                      ART OF ONCOLOGY

A Good Life Robert E. Fisher JCO Nov 2009: 5298–5299. First published on Jun 29 2009; 10.1200/JCO.2009.22.5854. [Full Text] [PDF]

                                      DIAGNOSIS IN ONCOLOGY

Granuloma Annulare Heralding Angioimmunoblastic T-Cell Lymphoma in a Patient With a History of Epstein-Barr Virus–Associated B-Cell Lymphoma Julie E. Martin, Andrew J. Wagner, George F. Murphy, Geraldine S. Pinkus, and Linda C. Wang JCO Nov 2009: e168–e171. First published on Sep 21 2009; 10.1200/JCO.2009.23.0409. [Full Text] [PDF]

                                      CORRESPONDENCE

Internal Mammary Node Radiation: A Proposed Technique to Spare Cardiac Toxicity Julia L. Oh and Thomas A. Buchholz JCO Nov 2009: e172–e173. First published on Jun 29 2009; 10.1200/JCO.2008.21.2787. [Full Text] [PDF]

Reply to J.L. Oh et al Ronald C. Chen, Jay R. Harris, and Jennifer R. Bellon JCO Nov 2009: e174. First published on Jun 29 2009; 10.1200/JCO.2009.22.3578. [Full Text] [PDF]

Classification of Philadelphia Translocation–Negative Myeloproliferative Neoplasms: Its Impact on Data From Clinical Trials Kikkeri N. Naresh JCO Nov 2009: e175–e176. First published on Aug 24 2009; 10.1200/JCO.2009.23.7198. [Full Text] [PDF]

Reply to K.N. Naresh Peter J. Campbell, David Bareford, Wendy N. Erber, Bridget S. Wilkins, Penny Wright, Georgina Buck, Keith Wheatley, Claire N. Harrison, and Anthony R. Green JCO Nov 2009: e177–e178. First published on Aug 24 2009; 10.1200/JCO.2009.23.7776. [Full Text] [PDF]

Locoregional Therapy Improves Survival for Metastatic Breast Cancer Patients? Benefit Remains Questionable! Dwan-Ying Chang, Ching-Hung Lin, and Yen-Shen Lu JCO Nov 2009: e179. First published on Sep 8 2009; 10.1200/JCO.2009.23.9962. [Full Text] [PDF]

Reply to D.-Y. Chang et al Romuald Le Scodan, Etienne Brain, and Denise Stevens JCO Nov 2009: e180. First published on Sep 8 2009; 10.1200/JCO.2009.24.0895. [Full Text] [PDF]

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.